Citation Impact
Citing Papers
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
2009
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase
2011 Science
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation
2009
IRE-1 and HSP-4 Contribute to Energy Homeostasis via Fasting-Induced Lipases in C. elegans
2009
Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species
2012 StandoutNobel
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
1997
Apoptosis in the nervous system
2000 StandoutNature
Targeting hypoxia in cancer therapy
2011 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Structural basis for triplet repeat disorders: a computational analysis
1999 StandoutNobel
The role of autophagy in neurodegenerative disease
2013 Standout
Huntington's disease
2007 Standout
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
2004 Standout
Synthetic lethal screen identification of chemosensitizer loci in cancer cells
2007 Nature
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Variations in the Efficiency of Lineage Marking and Ablation Confound Distinctions between Myogenic Cell Populations
2014
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
2015
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
2009 StandoutNobel
Autophagy: Renovation of Cells and Tissues
2011 Standout
Epigenetics and Bacterial Infections
2012
Huntingtin localization in brains of normal and Huntington's disease patients
1997
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Molecular Genetics of Huntington’s Disease
1998
Protein aggregation and neurodegenerative disease
2004 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Total Synthesis of (−)-Salicylihalamide
2001
Replicating Huntington's disease phenotype in experimental animals
1999
Minireview: The role of the vacuolar ATPase in nematodes
2011
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
2010
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
2012
Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription
2002
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology
2007
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations
2011
Autophagy in cell death: an innocent convict?
2005 Standout
Sensors and regulators of intracellular pH
2009 Standout
Autophagy: process and function
2007 Standout
VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations
2013
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
2000 Standout
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis
2016
The NCI60 human tumour cell line anticancer drug screen
2006 Standout
The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease
1998
The amyloid state and its association with protein misfolding diseases
2014 Standout
Salicylihalamide A Inhibits the V0 Sector of the V-ATPase through a Mechanism Distinct from Bafilomycin A1
2004
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
3d Transition Metals for C–H Activation
2018 Standout
Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition
1999
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Synthesis of Photoactivatable Acyclic Analogues of the Lobatamides
2005
Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice
2017
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Mild metal-catalyzed C–H activation: examples and concepts
2016 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation
1997 Standout
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Cobalt(III)-Catalyzed Directed C–H Allylation
2015
The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro
2001 StandoutNobel
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy
2008 StandoutNobel
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
2013 StandoutNobel
Transcriptional dysregulation in Huntington’s disease
2000
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Chemistry and Biology of Salicylihalamide A and Related Compounds
2003
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain
1997 StandoutScience
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
2001
The Emergence of Modern Neuroscience: Some Implications for Neurology and Psychiatry
2000 StandoutNobel
Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum
2001
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
2009
Total synthesis of (−)-salicylihalamide A and related congeners
2002
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Total Synthesis of the Salicylate Enamide Macrolide Oximidine II
2003
Works of Johnny Kim being referenced
Protein quality control gets muscle into shape
2008
Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells
2013
The Emerging Role of Epigenetic Modifiers Linking Cellular Metabolism and Gene Activity in Cardiac Progenitor Cells
2012
Prmt5 is a regulator of muscle stem cell expansion in adult mice
2015
The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy
2007
Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice
2021 Science
Epigenetic Modifications of Stem Cells
2011
Expression of Normal and Mutant Huntingtin in the Developing Brain
1996
Discovery of a Novel Antitumor Benzolactone Enamide Class That Selectively Inhibits Mammalian Vacuolar-Type (H+)-ATPases
2001