Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Youthful and age‐related matreotypes predict drugs promoting longevity
2021
In vivo aspects of protein folding and quality control
2016 Science
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
2023 Standout
The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach
2021 StandoutNobel
Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis
2022
NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells
2018
Mitochondria and Epigenetics – Crosstalk in Homeostasis and Stress
2017
The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans
2016
Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process
2019
A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans
2023 StandoutNobel
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response
2016
Parkinson disease
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
The mitochondrial UPR: mechanisms, physiological functions and implications in ageing
2017
Nrf2-Keap1 signaling in oxidative and reductive stress
2018 Standout
Increased fidelity of protein synthesis extends lifespan
2021
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
The glymphatic pathway in neurological disorders
2018 Standout
The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling
2018
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
IRE1 signaling exacerbates Alzheimer’s disease pathogenesis
2017
Hallmarks of aging: An expanding universe
2023 Standout
Metabolic Control of Longevity
2016
Ageing as a risk factor for neurodegenerative disease
2019 Standout
AI in health and medicine
2022 Standout
Cell-Nonautonomous Regulation of Proteostasis in Aging and Disease
2019
Quality Control of Membraneless Organelles
2018
Life’s Essential 8: Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association
2022 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Chronic Endurance Exercise Impairs Cardiac Structure and Function in Middle-Aged Mice with Impaired Nrf2 Signaling
2017
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response
2020 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
The Cellular Phase of Alzheimer’s Disease
2016
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
2019
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
2016
Oxidative Stress in Cancer
2020 Standout
Cellular Metabolism and Aging
2018
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
The quest to slow ageing through drug discovery
2020
Small vessel disease: mechanisms and clinical implications
2019 Standout
<p>Reactive Oxygen Species: Drivers of Physiological and Pathological Processes</p>
2020 Standout
The proteostasis network and its decline in ageing
2019
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
2020 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Quality control of glycoprotein folding and ERAD: the role of N-glycan handling, EDEM1 and OS-9
2016
Developmental ROS individualizes organismal stress resistance and lifespan
2019 Nature
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Aging Hallmarks and the Role of Oxidative Stress
2023
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
The integrated stress response
2016 Standout
A Tale of Two Concepts: Harmonizing the Free Radical and Antagonistic Pleiotropy Theories of Aging
2017
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association
2021 Standout
Alzheimer's disease
2017 Standout
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
2017 StandoutNobel
Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis
2019
Protein quality control in the secretory pathway
2019
A cullin-RING ubiquitin ligase promotes thermotolerance as part of the intracellular pathogen response in Caenorhabditis elegans
2020
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Proteostasis and aging
2015
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Cell non-autonomous regulation of health and longevity
2020
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
2021 Standout
Spermidine in health and disease
2018 StandoutScience
HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes
2019
Principles of Protein Stability and Their Application in Computational Design
2018
Walking the tightrope: proteostasis and neurodegenerative disease
2016
Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association
2017
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
Proteasomal and Autophagic Degradation Systems
2017
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of Johnathan Labbadia being referenced
Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging
2017
How the Mitoprotein-Induced Stress Response Safeguards the Cytosol: A Unified View
2020
Rethinking HSF1 in Stress, Development, and Organismal Health
2017
Using the drug-protein interactome to identify anti-ageing compounds for humans
2019
Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction
2015
The Biology of Proteostasis in Aging and Disease
2015