Citation Impact
Citing Papers
Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits
2001
Three-dimensional model of the human platelet integrin α IIb β 3 based on electron cryomicroscopy and x-ray crystallography
2002
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
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Ultrasound Reversibly Disaggregates Fibrin Fibers
1997
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
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Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
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Tough adhesives for diverse wet surfaces
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A Sulfilimine Bond Identified in Collagen IV
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Recreation of the terminal events in physiological integrin activation
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Tumour-cell invasion and migration: diversity and escape mechanisms
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Rational Design of Intercellular Adhesion Molecule-1 (ICAM-1) Variants for Antagonizing Integrin Lymphocyte Function-associated Antigen-1-dependent Adhesion
2005 StandoutNobel
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
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Modulation of Integrin Activation by an Entropic Spring in the β-Knee
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Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
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Mechanisms of Thrombus Formation
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Amino Acid Residues in the PSI Domain and Cysteine-rich Repeats of the Integrin β2 Subunit That Restrain Activation of the Integrin αxβ2
2001
Membrane-proximal α/β Stalk Interactions Differentially Regulate Integrin Activation
2005
Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement
2003
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
2002
Structural and Functional Studies with Antibodies to the Integrin β2 Subunit
2000
Sialic Acid Content of Plasminogen 2 Glycoforms as a Regulator of Fibrinolytic Activity
1995
Integrin activation and structural rearrangement
2002
Are changes in integrin affinity and conformation overemphasized?
1998
A reevaluation of integrins as regulators of angiogenesis
2002
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
The inner world of cell adhesion: integrin cytoplasmic domains
1994
Integrin αIIbβ3:ligand interactions are linked to binding‐site remodeling
2006
Structure of integrin 5 1 in complex with fibronectin
2003
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Two conformations of the integrin A-domain (I-domain): a pathway for activation?
1995
The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
2009 StandoutNobel
Scleroderma
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Angiogenesis in health and disease
2003 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Antiatherogenic properties of metformin: the experimental evidence
2003
Looking towards label-free biomolecular interaction analysis in a high-throughput format: a review of new surface plasmon resonance technologies
2006
Will the Real Integrin Please Stand Up?
2002
Factors affecting .gamma.-chain multimer formation in crosslinked fibrin
1992
Survey of the year 2000 commercial optical biosensor literature
2001
Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis
1996 Standout
Cohesive behavior of soft biological adhesives: Experiments and modeling
2012
Platelets in inflammation and atherogenesis
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Urokinase receptor: a molecular organizer in cellular communication
2000
The Conserved Membrane-proximal Region of an Integrin Cytoplasmic Domain Specifies Ligand Binding Affinity
1995
Molecular regulation of vessel maturation
2003 Standout
Topography of Ligand-induced Binding Sites, Including a Novel Cation-sensitive Epitope (AP5) at the Amino Terminus, of the Human Integrin β3 Subunit
1995
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
1995 StandoutNature
Involvement of the cooh-terminal portion of the alpha-chain of fibrin in the branching of fibers to form a clot
1987
Structural Basis of Collagen Recognition by Integrin α2β1
2000
Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
1996 Standout
Microenvironmental regulation of metastasis
2008 Standout
Adhesive signaling in platelets
1994
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1.
2001
Fibrinogen and fibrin: scaffold proteins in hemostasis
2007
Therapeutic antagonists and conformational regulation of integrin function
2003
Getting to the site of inflammation: the leukocyte adhesion cascade updated
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The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Integrins
2002 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
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Pro-angiogenic Activities of CYR61 (CCN1) Mediated through Integrins αvβ3 and α6β1 in Human Umbilical Vein Endothelial Cells
2002 Standout
Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling
2002
Transmembrane Domain Helix Packing Stabilizes Integrin αIIbβ3 in the Low Affinity State
2005
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Extracellular DNA traps promote thrombosis
2010 Standout
Guidelines for the Early Management of Patients With Acute Ischemic Stroke
2013 Standout
Platelet endothelial cell adhesion molecule-1 (PECAM-1 / CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development
1994
Epitope Mapping of Antibodies to the C-Terminal Region of the Integrin β2 Subunit Reveals Regions that Become Exposed Upon Receptor Activation
2001
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor.
1994
Binding strength and activation state of single fibrinogen-integrin pairs on living cells
2002
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
The GPIIb/IIIa (integrin αIIbβ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend
2008
Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering
2005
Crystal Structure of the Extracellular Segment of Integrin αVβ3
2001 Science
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Human Cartilage Repair with a Photoreactive Adhesive-Hydrogel Composite
2013
Imaging perfusion deficits, arterial patency and thrombolysis safety and efficacy in acute ischaemic stroke. Anobservational study of the effect of advanced imaging methods in The Third International Stroke Trial (IST-3), arandomised controlled trial
2014
Complementary Roles for Receptor Clustering and Conformational Change in the Adhesive and Signaling Functions of Integrin αIIbβ3
1998
Integrin activation takes shape
2002
Collagen Structure and Stability
2009 Standout
Modulation of CD11b/CD18 Adhesive Activity by Its Extracellular, Membrane-Proximal Regions
2003
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
A Naturally Occurring Extracellular α−β Clasp Contributes to Stabilization of β3 Integrins in a Bent, Resting Conformation
2008
A revolution in optical manipulation
2003 StandoutNature
Glycobiology: Toward Understanding the Function of Sugars
1996 Standout
Integrin Signaling
1999 StandoutScience
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand
2003
Mechanistic Diversity of Cytokine Receptor Signaling Across Cell Membranes
2004
Poly(ADP-Ribose) Polymerase Is Activated in Subjects at Risk of Developing Type 2 Diabetes and Is Associated With Impaired Vascular Reactivity
2002
Wound Healing: A Cellular Perspective
2018 Standout
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Conformational changes in tertiary structure near the ligand binding site of an integrin I domain
1999
Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII
2013 StandoutNobel
Design and applications of man-made biomimetic fibrillar hydrogels
2019
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Conformational Regulation of Integrin Structure and Function
2002
NMR Assignment and Secondary Structure Determination of an Octameric 110 kDa Protein Using TROSY in Triple Resonance Experiments
2000 StandoutNobel
Randomized, Controlled Trial of Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Intermediate-Risk Pulmonary Embolism
2013 Standout
Integrin-mediated cell adhesion: the extracellular face.
1994
The role of fragment X polymers in the fibrin enhancement of tissue plasminogen activator-catalyzed plasmin formation.
1990 StandoutNobel
Two Functional States of the CD11b A-Domain: Correlations with Key Features of Two Mn2+-complexed Crystal Structures
1998
Works of John W. Weisel being referenced
Role of the .alpha.C Domains of Fibrin in Clot Formation
1994
Ligand Binding Promotes the Entropy-driven Oligomerization of Integrin αIIbβ3
2003
The electron microscope band pattern of human fibrin: Various stains, lateral order, and carbohydrate localization
1986
Novel Interactions between Urokinase and Its Receptor
2000
Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes
2009
Binding of a fibrinogen mimetic stabilizes integrin αIIbβ3's open conformation
2001
Long range propagation of conformational changes in integrin alpha IIb beta 3.
1993
Fibrinogen Sialic Acid Residues Are Low Affinity Calcium-binding Sites That Influence Fibrin Assembly
1989
The Effect of Dimethylbiguanide on Thrombin Activity, FXIII Activation, Fibrin Polymerization, and Fibrin Clot Formation
2002
Effects of Ligand-Mimetic Peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on αIIbβ3 Integrin Conformation and Oligomerization
1999