Citation Impact
Citing Papers
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
Why do cancers have high aerobic glycolysis?
2004 Standout
Cellular interactions in metastasis
1990
Concurrent Cisplatin-Based Radiotherapy and Chemotherapy for Locally Advanced Cervical Cancer
1999 Standout
The implications of angiogenesis for the biology and therapy of cancer metastasis
1994 Standout
The Cellular Basis of Tumor Progression
1997
Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects
1990
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
1990 Standout
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
It Takes a Tissue to Make a Tumor: Epigenetics, Cancer and the Microenvironment
2001
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
2013
Technical considerations for studying cancer metastasis in vivo
1997
Dissemination and growth of cancer cells in metastatic sites
2002 Standout
Tumor heterogeneity: Causes and consequences
2009
Tumorigenesis: it takes a village
2015
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
1989 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Stimuli-responsive nanocarriers for drug delivery
2013 Standout
Spontaneous losses of control of cytokeratin gene expression in transformed, non-epithelial human cells occurring at different levels of regulation
1989
Microenvironmental and cellular consequences of altered blood flow in tumours
2003
A Comparison of Multimodal Therapy and Surgery for Esophageal Adenocarcinoma
1996 Standout
Cancer nanotechnology: opportunities and challenges
2005 Standout
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Hormonal suppression for fertility preservation in males and females
2008
Histone deacetylase inhibitors and genomic instability
2008
Reversible transition towards a fibroblastic phenotype in a rat carcinoma cell line
1989
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
2003 Standout
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Analysis of glutathione: implication in redox and detoxification
2003
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
EMT: 2016
2016 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Effect of cisplatin on the clinically relevant radiosensitivity of human cervical carcinoma cell lines
1996
An evolutionary-game model of tumour–cell interactions: possible relevance to gene therapy
2001
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
1991 Standout
Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self
1988
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
1995
Clonal evolution in cancer
2012 StandoutNature
Biomarkers for epithelial-mesenchymal transitions
2009 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Cancer as an evolutionary and ecological process
2006 Standout
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Preservation of Fertility in Patients with Cancer
2009 Standout
Karnofsky memorial lecture. Conceptual and practical advances in the management of breast cancer.
1989
Radiation and the microenvironment – tumorigenesis and therapy
2005
Combined radiation and chemotherapy as primary management of adenocarcinoma of the esophagus and gastroesophageal junction
1988
Experimental systems for analysis of the malignant phenotype
1982
An evolutionary model of carcinogenesis.
2003
Tumor subpopulation interactions in neoplasms
1983
Inverse relationship between human papillomavirus (HPV) type 16 early gene expression and cell differentiation in nude mouse epithelial cysts and tumors induced by HPV-positive human cell lines
1991 StandoutNobel
The Radiation Response of a Human Colon Adenocarcinoma Grown in Monolayer, as Spheroids, and in Nude Mice
1987
Lymphatic Mapping and Sentinel Node Biopsy in the Patient With Breast Cancer
1996 Standout
Intercapillary distance in the proliferating area of human glioma.
1988
Hypoxia-induced bFGF gene expression is mediated through the JNK signal transduction pathway
1999
BCNU-modification of the in vitro radiation response in 9L brain tumor cells of rats
1977
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
2003 Standout
G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.
1993 StandoutNobel
DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas.
1980 StandoutNobel
Evidence that intravenously derived murine pulmonary melanoma metastases can originate from the expansion of a single tumor cell.
1986
Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies
1985
The glucose distribution in 9l rat brain multicell tumor spheroids and its effect on cell necrosis
1982
Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture.
1990
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
1988 StandoutScience
A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas.
2000
In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa.
1988
A minority of carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression.
1994
Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker.
1998
Metabolic reprogramming and cancer progression
2020 StandoutScience
Interaction between two cellular subpopulations of a rat colonic carcinoma when inoculated to the syngeneic host
1985
beta1 integrin as a molecular therapeutic target
2007
Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis
1986
Control of Intracerebral Gliosarcomas in Rats by Boron Neutron Capture Therapy with p-Boronophenylalanine
1992
Cancer Genome Landscapes
2013 StandoutScience
The biology of cancer metastasis and implications for therapy
1987
p63 identifies keratinocyte stem cells
2001 Standout
The Chemistry of Neutron Capture Therapy
1998 Standout
Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells.
2000
Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know
2003 Standout
Digital Switching of Local Arginine Density in a Genetically Encoded Self-Assembled Polypeptide Nanoparticle Controls Cellular Uptake
2012
Tumor hypoxia: its impact on cancer therapy
1987
Modulation of tumor cell response to chemotherapy by the organ environment
1994
Biological Diversity in Metastatic Neoplasms: Origins and Implications
1982 Science
Generation of phenotypic diversity and progression in metastatic tumor cells
1984
Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice
2014 Standout
Evolution of cooperation among tumor cells
2006
Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy.
2002
A comparison of cell replacement in bone marrow, testis and three regions of surface epithelium
1979
Cell Replacement in Epidermis (Keratopoiesis) via Discrete Units of Proliferation
1981
Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells.
1981
Glucocorticoid-Induced TNF Receptor Family Related Gene Activation Overcomes Tolerance/Ignorance to Melanoma Differentiation Antigens and Enhances Antitumor Immunity
2006 StandoutNobel
Works of John T. Leith being referenced
Design and implementation of a web service-oriented gateway to facilitate environmental modeling using HPC resources
1980
Secretion rates and levels of vascular endothelial growth factor in clone A or HCT‐8 human colon tumour cells as a function of oxygen concentration
1995
X ray responses of a human colon tumor cell line after exposure to the differentiation-inducing agent N-methylformamide: Concentration dependence and reversibility characteristics
1988
Gonadotropin‐Releasing Hormone Antagonist (Cetrorelix) Therapy Fails to Protect Nonhuman Primates (Macaca arctoides) From Radiation‐Induced Spermatogenic Failure
2005
Dormancy, Regression, and Recurrence: Towards a Unifying Theory of Tumor Growth Control
1994
Autocrine and paracrine growth factors in tumor growth: A mathematical model
1991
Tumor micro-ecology and competitive interactions
1987
Erythrocyte glutathione and tumour response to chemotherapy
1992
Enhancement of radiation injury in human colon tumor cells by the maturational agent sodium butyrate (NaB).
1985
Effects of the Differentiating Agents Sodium Butyrate and N-Methylformamide on the Oxygen Enhancement Ratio of Human Colon Tumor Cells
1988
Alteration of the survival response of two human colon carcinoma subpopulations to x-irradiation by N,N-dimethylformamide.
1982
Enhancement of Radiation Injury in Human Colon Tumor Cells by the Maturational Agent Sodium Butyrate (NaB)
1985
Enhancement of the responses of human colon adenocarcinoma cells to X-irradiation and cis-platinum by N-methylformamide (NMF)
1985
Tumor heterogeneity and drug resistance.
1986
Host response in tumor growth and progression.
1996
Selective modification of the X ray survival response of two mouse mammary adenocarcinoma sublines by N,N-dimethylformamide
1981
Response of a human colon adenocarcinoma (DLD-1) to X irradiation and mitomycin C in vivo
1983
Cellular radiosensitivity of a rat brain tumor
1975
Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.
1985
Similarity of Thermotolerance Characteristics in Heterogeneous Human Colon Tumor Subpopulations after Exposure to Fractionated Heat Doses (44°C)
1985
Tumor radiocurability: relationship to intrinsic tumor heterogeneity and to the tumor bed effect.
1990
Survival of Mouse-skin Epithelial Cells after Heavy-particle Irradiation
1971
Mammalian Tumor Cell Heterogeneity
1986
Intrinsic and extrinsic heterogeneity in the responses of parent and clonal human colon carcinoma xenografts to photon irradiation.
1984
Growth properties of artificial heterogeneous human colon tumors.
1987
Compositional stability of artificial heterogeneous tumors in vivo: use of mitomycin C as a cytotoxic probe.
1988
Autocrine and paracrine growth factors in tumor growth: A mathematical model
1991