Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Evidence of a Role for Insulin-Like Growth Factor Binding Protein (IGFBP)-3 in Metabolic Regulation
2010
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Human conditions of insulin-like growth factor-I (IGF-I) deficiency
2012
Stellate Cell Activation in Alcoholic Pancreatitis
2003
Insulin-induced Activation of NADPH-dependent H2O2 Generation in Human Adipocyte Plasma Membranes Is Mediated by Gαi2
1997
Nonalcoholic Fatty Liver Disease: From Steatosis to Cirrhosis
2006 Standout
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
Bone Turnover and Insulin-like Growth Factor I Levels Increase After Improved Glycemic Control in Noninsulin-dependent Diabetes Mellitus
1998
Early Hepatic Stellate Cell Activation Predicts Severe Hepatitis C Recurrence after Liver Transplantation
2005
Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC)
2013 Standout
TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells
2001
Cellular and molecular mechanisms of fibrosis
2007 Standout
Liver fibrosis
2005 Standout
Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing
2008 Standout
The Global Impact of Hepatic Fibrosis and End-Stage Liver Disease
2008
Mechanisms of liver fibrosis
2005
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Interleukin‐18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K‐Akt‐dependent NF‐κB activation
2007
Real-world effectiveness of 8-week treatment with ledipasvir/sofosbuvir in chronic hepatitis C
2017
Does the natriuretic peptide system exist throughout the animal and plant kingdom?
2001
Metabolic, anabolic, and mitogenic insulin responses: A tissue-specific perspective for insulin receptor activators
2015
Adrenomedullin, endothelin, neuropeptide Y, atrial, brain, and C-natriuretic prohormone peptides compared as early heart failure indicators1
1997
Administration of the potent PPARα agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice
2004
Bariatric Surgery versus Intensive Medical Therapy for Diabetes — 5-Year Outcomes
2017 Standout
Drug-Induced Hepatotoxicity
2003 Standout
Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin.
1989
Molecular Pathogenesis of Alcohol‐Induced Hepatic Fibrosis
2005
In vitro studies on the action of CS-045, a new antidiabetic agent
1990
An Insulin-like Signaling Pathway Affects Both Longevity and Reproduction in Caenorhabditis elegans
1998 StandoutNobel
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Acute Pancreatitis
2016 Standout
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
1996
Transcriptional regulation of hepatic stellate cell activation: Figure 1
2002
Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
2006 Standout
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans.
1993
Enhanced γ-Glutamyl Transpeptidase Expression and Selective Loss of CuZn Superoxide Dismutase in Hepatic Iron Overload
1998
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Regulation of rat hepatic low density lipoprotein receptors. In vivo stimulation by growth hormone is not mediated by insulin-like growth factor I.
1996
Role of stellate cells in pancreatic fibrogenesis associated with acute and chronic pancreatitis
2006
A rapid bedside test for B-type peptide predicts treatment outcomes in patients admitted for decompensated heart failure: a pilot study
2001 Standout
A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload
2001 Standout
Endocrine Regulation of Energy Metabolism by the Skeleton
2007 Standout
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Effectiveness of hepatitis C antiviral treatment in a USA cohort of veteran patients with hepatocellular carcinoma
2017
Transcriptional regulation of hepatic stellate cells
2009
Transcriptional regulation of stellate cell activation
2006
Intrahepatic gene expression profiles and alpha‐smooth muscle actin patterns in hepatitis C virus induced fibrosis†
2005
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste
2004 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Dynamics of Hepatitis C Virus Replication in Human Liver
2003
The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
2012 Standout
β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression
2007 StandoutNobel
Non-invasive assessment of liver fibrosis progression in hepatitis C patients retreated for 96 weeks with antiviral therapy: a randomized study
2010
Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies
2013
Disorders of Iron Metabolism
1999 Standout
Potential of Surgery for Curing Type 2 Diabetes Mellitus
2002
The stress-activated protein kinase pathways
1999
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Diagnosis and management of hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases
2011
Molecular and Cellular Aspects of the Insulin-Like Growth Factor I Receptor
1995
Genetic Risk Factors for Pancreatic Disorders
2013
HEPATIC FIBROSIS
2001
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Evaluation of Liver Fibrosis: A Concise Review
2004
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells
2001 StandoutNobel
Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis
2008
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver
2017
An obligatory requirement for the heterotrimeric G protein G i3 in the antiautophagic action of insulin in the liver
2007
Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C
2005 StandoutNobel
Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
2004 Standout
Management of Hemochromatosis
1998
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*
1997 Standout
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
2002 Standout
The specificities of protein kinase inhibitors: an update
2003 Standout
Quasispecies Heterogeneity within the E1/E2 Region as a Pretreatment Variable during Pegylated Interferon Therapy of Chronic Hepatitis C Virus Infection
2005
A Genome-Based Resource for Molecular Cardiovascular Medicine
1997
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Mathematical Modeling of Subgenomic Hepatitis C Virus Replication in Huh-7 Cells
2006 StandoutNobel
EASL Recommendations on Treatment of Hepatitis C 2018
2018 Standout
Hepatocyte proliferation during liver regeneration is impaired in mice with liver‐specific IGF‐1R knockout
2006
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
2012 Standout
Cross-talk between the insulin and angiotensin signaling systems.
1996
Molecular Mechanisms of Myocardial Remodeling
1999 Standout
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Insulin-Like Growth Factors Stimulate Expression of Hepatocyte Growth Factor But Not Transforming Growth Factor β1 in Cultured Hepatic Stellate Cells*
1997
Eight weeks of ledipasvir/sofosbuvir is effective for selected patients with genotype 1 hepatitis C virus infection
2016
Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis
2002
Works of John Poulos being referenced
Safety and efficacy of ledipasvir‐sofosbuvir in black patients with hepatitis C virus infection: A retrospective analysis of phase 3 data
2015
Repetitive Self-Limited Acute Pancreatitis Induces Pancreatic Fibrogenesis in the Mouse
2000
Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver.
1988
The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells
2003
Comparison of Genetic Heterogeneity of Hepatitis C Viral Rna in Liver Tissue and Serum
1999
Liver Transplantation for Hereditary Hemochromatosis
1996
Atrial Natriuretic Peptide Gene Expression within Invertebrate Hearts
1995
Circulating Insulin-Like Growth Factor I Concentrations in Clinically Severe Obese Patients With and Without NIDDM in Response to Weight Loss
1994
Guanine nucleotide binding regulatory proteins in liver from obese humans with and without type II diabetes: Evidence for altered “cross‐talk” between the insulin receptor and Gi‐proteins
1994
Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells
1997
Nefazodone-Induced Liver Failure: Report of Three Cases
1999
Congestive heart failure: increased cardiac and extracardiac atrial natriuretic peptide gene expression
1996
Effect of vitamin E supplementation on hepatic fibrogenesis in chronic dietary iron overload
1997
Hepatic alpha-smooth muscle actin expression in hepatitis C patients before and after interferon therapy.
2001