Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen
2016
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes
2006 StandoutScience
Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
2011 Standout
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin
2006 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Spontaneous regression of human melanoma/nonmelanoma skin cancer: Association with infiltrating CD4+ T cells
1995
Progress in human tumour immunology and immunotherapy
2001 Nature
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
1998 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Immunosuppressive networks in the tumour environment and their therapeutic relevance
2005 Standout
Tumor Eradication by Adoptive Transfer of Cytototic T Lymphocytes
1992
The immune cell infiltrate populating meningiomas is composed of mature, antigen-experienced T and B cells
2013
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Imaging in the era of molecular oncology
2008 StandoutNature
Apoptosis by Death Factor
1997 Standout
The Principles of Engineering Immune Cells to Treat Cancer
2017
Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity
1995
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction
1990
Human tumor antigens recognized by T-cells
1997
Cancer vaccines based on the identification of genes encoding cancer regression antigens
1997
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
2014
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
2008
Minimally Cultured Tumor-infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy
2008
Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?
2011
Angiogenesis in life, disease and medicine
2005 StandoutNature
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
Human tumor antigens for cancer vaccine development
1999
Cancer immunotherapy comes of age
2011 StandoutNature
Retroviral vectors displaying functional antibody fragments
1993 StandoutNobel
Adoptive T Cell Immunotherapy For Cancer
2015
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells
1991
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
2001 StandoutNature
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
The use of anti-CD3 and anti-CD28 monoclonal antibodies to clone and expand human antigen-specific T cells
1990
Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy
2017
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Adoptive cell therapy for the treatment of patients with metastatic melanoma
2009
Adoptive Transfer of Cloned Melanoma-Reactive T Lymphocytes for the Treatment of Patients with Metastatic Melanoma
2001
Lymphokine gene therapy for cancer
1990
Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance
1999
Transfer of a TCR Gene Derived from a Patient with a Marked Antitumor Response Conveys Highly Active T-Cell Effector Functions
2005
IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases.
1995
A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes.
1996
A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian Cancer
2006
A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability.
1992
Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.
1994
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
2002 StandoutScience
Messenger RNA-Electroporated Dendritic Cells Presenting MAGE-A3 Simultaneously in HLA Class I and Class II Molecules
2004
High Efficiency TCR Gene Transfer into Primary Human Lymphocytes Affords Avid Recognition of Melanoma Tumor Antigen Glycoprotein 100 and Does Not Alter the Recognition of Autologous Melanoma Antigens
2003
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens
1999
A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma
1991 StandoutScience
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Cytokine enhancement of DNA immunization leads to effective treatment of established pulmonary metastases.
1996
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Treatment of 283 Consecutive Patients With Metastatic Melanoma or Renal Cell Cancer Using High-Dose Bolus Interleukin 2
1994
Recognition of multiple epitopes in the human melanoma antigen gp100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides.
1995
Therapeutic Targeting of the Tumor Microenvironment
2021
Primary Human Lymphocytes Transduced with NY-ESO-1 Antigen-Specific TCR Genes Recognize and Kill Diverse Human Tumor Cell Lines
2005
Death Receptors: Signaling and Modulation
1998 StandoutScience
Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.
1994
Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity.
1996
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
The Basic Science of Gene Therapy
1993 Science
Chimeric Antigen Receptor Therapy
2018 Standout
Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.
1990
Metabolic reprogramming and cancer progression
2020 StandoutScience
Synthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signal
2014
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.
1994
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape
1996 Science
HUMAN T CELL RESPONSES AGAINST MELANOMA
2005
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.
1994
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
IL-2: The First Effective Immunotherapy for Human Cancer
2014
T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells
2002
CAR T cell immunotherapy for human cancer
2018 StandoutScience
A Phase I Study of Nonmyeloablative Chemotherapy and Adoptive Transfer of Autologous Tumor Antigen-Specific T Lymphocytes in Patients With Metastatic Melanoma
2002
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Works of John P. Wei being referenced
Localization of111Indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response
1994
Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma
1988 Standout