Standout Papers
Citation Impact
Citing Papers
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
Nanoparticle Targeting of Anticancer Drug Improves Therapeutic Response in Animal Model of Human Epithelial Cancer
2005
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
2009 Standout
Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
2013
Metabolomic NMR Fingerprinting to Identify and Predict Survival of Patients with Metastatic Colorectal Cancer
2011
Plasma β-amyloid in Alzheimer’s disease and vascular disease
2016 StandoutNobel
Stability of person-specific blood-based infrared molecular fingerprints opens up prospects for health monitoring
2021 StandoutNobel
Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
2019
Urinary Metabolite Markers of Precocious Puberty
2011
IPO: a tool for automated optimization of XCMS parameters
2015
Metabolomic Changes Accompanying Transformation and Acquisition of Metastatic Potential in a Syngeneic Mouse Mammary Tumor Model
2010
Hyaluronic Acid Hydrogels for Biomedical Applications
2011 Standout
Automation of measurements and data evaluation in biomolecular NMR screening
2001
MetaboAnalyst: a web server for metabolomic data analysis and interpretation
2009 Standout
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk
2013 Standout
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues
2003
Plasma phospholipids identify antecedent memory impairment in older adults
2014
Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease
2015
Elemental formula annotation of polar and lipophilic metabolites using 13 C, 15 N and 34 S isotope labelling, in combination with high‐resolution mass spectrometry
2011
Use of solid-phase microextraction coupled to gas chromatography–mass spectrometry for determination of urinary volatile organic compounds in autistic children compared with healthy controls
2014
Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes
2008
Hallmarks of aging: An expanding universe
2023 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Ultra Performance Liquid Chromatography and High Resolution Mass Spectrometry for the Analysis of Plant Lipids
2011
Pre-analytic Considerations for Mass Spectrometry-Based Untargeted Metabolomics Data
2019
Drug-Induced Hepatotoxicity
2003 Standout
Nearest neighbor effects on carcinogen binding to guanine runs in DNA
1991
Nanocarriers as an emerging platform for cancer therapy
2007 Standout
Differential Stabilization of Eukaryotic DNA Topoisomerase I Cleavable Complexes by Camptothecin Derivatives
1995 StandoutNobel
Identification of sulfation sites of metabolites and prediction of the compounds’ biological effects
2006
Accurate, Fully-Automated NMR Spectral Profiling for Metabolomics
2015
Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues
2015 StandoutNobel
Metagenomic biomarker discovery and explanation
2011 Standout
Metabonomics: a platform for studying drug toxicity and gene function
2002 Standout
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
2007 Standout
Metabolomics Data Normalization with EigenMS
2014
An introduction to biological nuclear magnetic resonance spectroscopy
2010
Pharmaco-metabonomic phenotyping and personalized drug treatment
2006 Nature
Gas chromatography/flame ionisation detection mass spectrometry for the detection of endogenous urine metabolites for metabonomic studies and its use as a complementary tool to nuclear magnetic resonance spectroscopy
2006 StandoutNobel
Global strategies to integrate the proteome and metabolome
2005
Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
2012
Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm
1993 StandoutNobel
Long term conservation of human metabolic phenotypes and link to heritability
2014
Alzheimer's disease
2016 Standout
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
2010
The Human Microbiome Project
2007 StandoutNature
Metabolic phenotyping in clinical and surgical environments
2012 Nature
Directly coupled HPLC–NMR and HPLC–NMR–MS in pharmaceutical research and development
2000
Optimisation of collection, storage and preparation of rat plasma for 1H NMR spectroscopic analysis in toxicology studies to determine inherent variation in biochemical profiles
2002
Mammalian aldehyde oxidases: genetics, evolution and biochemistry
2007
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
MetaboAnalyst 3.0—making metabolomics more meaningful
2015 Standout
Specified Species in Gingival Crevicular Fluid Predict Bacterial Diversity
2010
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
2011 Standout
Nmr in drug discovery
2002 StandoutNobel
Detection of Resistance to Imatinib by Metabolic Profiling
2005
Fingerprinting food: current technologies for the detection of food adulteration and contamination
2012 Standout
A critical review of the state of the art of solid-phase microextraction of complex matrices III. Bioanalytical and clinical applications
2015
Nuclear Magnetic Resonance Metabolomic Footprinting of Human Hepatic Stem Cells and Hepatoblasts Cultured in Hyaluronan-Matrix Hydrogels
2008
Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans
2014 StandoutNobel
Classification of olive oils using high throughput flow 1H NMR fingerprinting with principal component analysis, linear discriminant analysis and probabilistic neural networks
2005
The Consortium for Metabonomic Toxicology (COMET): Aims, Activities and Achievements
2005
Prediction and Classification of Drug Toxicity Using Probabilistic Modeling of Temporal Metabolic Data: The Consortium on Metabonomic Toxicology Screening Approach
2007
Virtual Chromatographic Resolution Enhancement in Cryoflow LC−NMR Experiments via Statistical Total Correlation Spectroscopy
2007
Highly Integrated Nano-Platform for Breaking the Barrier between Chemotherapy and Immunotherapy
2016
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
2001
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Comparative Analysis of Sample Preparation Methods To Handle the Complexity of the Blood Fluid Metabolome: When Less Is More
2012
Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently
2019
Helicenes: Synthesis and Applications
2011 Standout
Spermidine in health and disease
2018 StandoutScience
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
The synthesis of novel polycyclic heterocyclic ring systems via photocyclization. 7. [1]Benzothieno[2,3‐c]naphtho[2,1‐h]quinoline and [1]benzothieno[2,3‐c]naphtho[2,1‐h][1,2,4]triazolo[4,3‐a]quinoline
1992
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
2018 Standout
13C NMR Spectra of pentacyclic triterpenoids—a compilation and some salient features
1994 Standout
Susceptibility of Human Metabolic Phenotypes to Dietary Modulation
2006
Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach
2008 StandoutNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model
2007
Rapid metabolic evolution in human prefrontal cortex
2011 StandoutNobel
The Mononuclear Molybdenum Enzymes
2014 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Detection and characterization of a glutathione conjugate of a novel copper complex.
2009
Analytical Reproducibility in 1H NMR-Based Metabonomic Urinalysis
2002
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Pattern recognition methods and applications in biomedical magnetic resonance
2001
Photochromism of Diarylethene Molecules and Crystals: Memories, Switches, and Actuators
2014 Standout
Effects of DNA methylation on topoisomerase I and II cleavage activities.
1994 StandoutNobel
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Metabolomics for Investigating Physiological and Pathophysiological Processes
2019
Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids
2000
Reversible Optical Rotation Change According to the Enantiospecific Photochromic Reaction of [2.2]Metacyclophan-1-ene
2004
Solvent-Dependent Metabolite Distribution, Clustering, and Protein Extraction for Serum Profiling with Mass Spectrometry
2005
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Statistical Heterospectroscopy, an Approach to the Integrated Analysis of NMR and UPLC-MS Data Sets: Application in Metabonomic Toxicology Studies
2005
Analysis of the Human Adult Urinary Metabolome Variations with Age, Body Mass Index, and Gender by Implementing a Comprehensive Workflow for Univariate and OPLS Statistical Analyses
2015
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics
2020
METLIN
2005 Standout
Molecular imprinting: perspectives and applications
2016 Standout
From Exogenous to Endogenous: The Inevitable Imprint of Mass Spectrometry in Metabolomics
2006
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of John P. Shockcor being referenced
The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra‐performance liquid chromatography/orthogonal acceleration time‐of‐flight mass spectrometry
2006
Properties of aflatoxin—DNA adducts formed by photoactivation and characterization of the major photoadduct as aflatoxin—N7-guanine
1990
Metabonomic Applications in Toxicity Screening and Disease Diagnosis
2002
Application of directly coupled LC–NMR–MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83
2000
NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man
1997
Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat
1999
MS E with mass defect filtering for in vitro and in vivo metabolite identification
2007
Hplc-nmr identification of the human urinary metabolites of (—)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV)
1996
Metabolomics as a tool for cardiac research
2011
Comparative metabonomics of differential hydrazine toxicity in the rat and mouse
2004
Characterization ofin vitrometabolites from human liver microsomes using directly coupled hplc-nmr: application to a phenoxathiin monoamine oxidase-A inhibitor
1996
Global metabolic profiling of animal and human tissues via UPLC-MS
2012
Metabolic profiles of cancer cells
2004
Global metabolic profiling procedures for urine using UPLC–MS
2010 Standout
Flow Injection Proton Nuclear Magnetic Resonance Spectroscopy Combined With Pattern Recognition Methods: Implications for Rapid Structural Studies and High Throughput Biochemical Screening
1997
Disentangling proton connectivity networks in highly overlapped1H‐NMR spectra of polynuclear aromatics using 1D‐HOHAHA
1990
Detection of in vivo biomarkers of phospholipidosis using NMR‐based metabonomic approaches
2001
Disposition of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘- (methylsulfonyl)-[1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)- 1H-pyrazole-5-carboxamide (DPC 423) by Novel Metabolic Pathways. Characterization of Unusual Metabolites by Liquid Chromatography/Mass Spectrometry and NMR
2001
Metabonomic Investigations into Hydrazine Toxicity in the Rat
2001
Visualization of GC/TOF-MS-Based Metabolomics Data for Identification of Biochemically Interesting Compounds Using OPLS Class Models
2007 Standout
Protein and Nonprotein Cysteinyl Thiol Modification by N-Acetyl-p-benzoquinone Imine via a Novel Ipso Adduct
1999
Novel Application of Reversed-Phase UPLC-oaTOF-MS for Lipid Analysis in Complex Biological Mixtures: A New Tool for Lipidomics
2006
The synthesis of novel polycyclic heterocyclic ring systems via photocyclization. 11. Synthesis and total assignment of the 1H and 13C NMR spectra of isomeric benzothienonaphthoquinolines using multiple inverse detected two‐dimensional NMR methods
1993
A combined1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-α null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome
2006
Disposition of Glutathione Conjugates in Rats by a Novel Glutamic Acid Pathway: Characterization of Unique Peptide Conjugates by Liquid Chromatography/Mass Spectrometry and Liquid Chromatography/NMR
2000
Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor, (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3,4-dihydro-2(1H)-quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne
2000
High performance liquid chromatography coupled to nuclear magnetic resonance spectroscopy and mass spectrometry applied to plant products: Identification of ecdysteroids fromSilene otites
1999
Strategy for Optimizing LC-MS Data Processing in Metabolomics: A Design of Experiments Approach
2012
P450-Mediated Metabolism of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole- 5-carboxamide (DPC 423) and Its Analogues to Aldoximes. Characterization of Glutathione Conjugates of Postulated Intermediates Derived from Aldoximes
2001
Combined HPLC, NMR Spectroscopy, and Ion-Trap Mass Spectrometry with Application to the Detection and Characterization of Xenobiotic and Endogenous Metabolites in Human Urine
1996
1D HMQC-tocsy: A selective one-dimensional analogue of HMQ-TOCSY
1990