Standout Papers
Citation Impact
Citing Papers
On the relationship between folding and chemical landscapes in enzyme catalysis
2008 StandoutNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Lessons from application of the UNRES force field to predictions of structures of CASP10 targets
2013
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Protein Conformational Switches: From Nature to Design
2012
Conversion of monomeric protein L to an obligate dimer by computational protein design
2001 StandoutNobel
Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain
2001
A Thermodynamic Scale for the .beta.-Sheet Forming Tendencies of the Amino Acids
1994
A short linear peptide that folds into a native stable β-hairpin in aqueous solution
1994
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Context-dependent secondary structure formation of a designed protein sequence
1996 Nature
Critical role of beta-hairpin formation in protein G folding.
2000 StandoutNobel
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Characterization of the free energy spectrum of peptostreptococcal protein L
1997 StandoutNobel
Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain
1998
Folding and stability of a tryptophan-containing mutant of ubiquitin
1993
A tale of two secondary structure elements: when a β-hairpin becomes an α-helix 1 1Edited by A. R. Fersht
1999
Nucleation mechanisms in protein folding
1997
Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations
2014
Folding of a model three-helix bundle protein: a thermodynamic and kinetic analysis 1 1Edited by A. R. Fersht
1999 StandoutNobel
Loop length, intramolecular diffusion and protein folding
1997
Design, structure and stability of a hyperthermophilic protein variant
1998
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Catalysis of a protein folding reaction: Thermodynamic and kinetic analysis of subtilisin BPN' interactions with its propeptide fragment
1993
Context is a major determinant of β-sheet propensity
1994 Nature
Different folding transition states may result in the same native structure
1996
Denaturant m values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding
1995 Standout
The barriers in protein folding
1994
Fast and Slow Intermediate Accumulation and the Initial Barrier Mechanism in Protein Folding
2002
Protein folding in the landscape perspective: Chevron plots and non-arrhenius kinetics
1998
Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: Secondary structure propensities are not conserved in proteins with the same fold
1997
Aromatic rescue of glycine in β sheets
1998
Sensitivity of hydrogen bonds of DNA and RNA to hydration, as gauged by 1 J NH measurements in ethanol–water mixtures
2007
Protein folding and misfolding
2003 StandoutNature
Molecular dynamics simulations of peptides and proteins with a continuum electrostatic model based on screened Coulomb potentials
2003
RNA structure and NMR spectroscopy
1991
Conserved residues and the mechanism of protein folding
1996 Nature
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Favourable native-like helical local interactions can accelerate protein folding
1997
Extremely rapid protein folding in the absence of intermediates
1995
Direct evidence for a two‐state protein unfolding transition from hydrogen‐deuterium exchange, mass spectrometry, and NMR
1996 StandoutNobel
Structured States of Disordered Proteins from Genomic Sequences
2016
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Fast and slow tracks in lysozyme folding: insight into the role of domains in the folding process
1997
Engineering Protein Switches: Sensors, Regulators, and Spare Parts for Biology and Biotechnology
2011
Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy
1998
Molecular collapse: The rate-limiting step in two-state cytochrome c folding
1996
The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP.
1999
A molecular dynamics simulation study of segment B1 of protein G
1997
Contact order, transition state placement and the refolding rates of single domain proteins 1 1Edited by P. E. Wright
1998 StandoutNobel
Complementation of peptide fragments of the single domain protein chymotrypsin inhibitor 2
1997
Coupling backbone flexibility and amino acid sequence selection in protein design
1997
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Detection of rare partially folded molecules in equilibrium with the native conformation of RNaseH
1996
Design of protein conformational switches
2006
De novo design of the hydrophobic cores of proteins
1995
The origins of asymmetry in the folding transition states of protein L and protein G
2002
Obligatory steps in protein folding and the conformational diversity of the transition state
1998
Measurement of the β-sheet-forming propensities of amino acids
1994 Nature
Kinetic role of early intermediates in protein folding
1997
The sequences of small proteins are not extensively optimized for rapid folding by natural selection
1998 StandoutNobel
SITE-SPECIFIC DYNAMICS IN DNA:Experiments
1997
Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability
1997 StandoutNobel
A systematic exploration of the influence of the protein stability on amyloid fibril formation in vitro
2000
Computational method to reduce the search space for directed protein evolution
2001 StandoutNobel
Single-Molecule Fluorescence Studies of Protein Folding and Conformational Dynamics
2006
Strategies for the Total Synthesis of C2−C11 Cyclized Cembranoids
2008
Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions
2018 StandoutNobel
Molecular dynamics study of entangled hard-chain fluids
1996
The Periplasmic Domain of TolR from Haemophilus influenzae Forms a Dimer with a Large Hydrophobic Groove: NMR Solution Structure and Comparison to SAXS Data,
2008
Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures
1999 StandoutNobel
Structure-based conformational preferences of amino acids
1999 StandoutNobel
First-Principles Calculation of the Folding Free Energy of a Three-Helix Bundle Protein
1995 Science
Submillisecond folding of monomeric lambda repressor.
1995
Proton nuclear magnetic resonance sequential assignments and secondary structure of an immunoglobulin light chain-binding domain of protein L
1993
Transient aggregates in protein folding are easily mistaken for folding intermediates
1997
Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2
1996
Funnel sculpting for in silico assembly of secondary structure elements of proteins
2003 StandoutNobel
Two Crystal Structures of the B1 Immunoglobulin-Binding Domain of Streptococcal Protein G and Comparison with NMR
1994
Native protein sequences are close to optimal for their structures
2000 StandoutNobel
Long-range order in the src SH3 folding transition state
2000 StandoutNobel
Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications.
1995
Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability
2007 StandoutNobel
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Architecture and function of metallopeptidase catalytic domains
2013
Substrate Binding and Catalysis by Ubiquitin C-Terminal Hydrolases: Identification of Two Active Site Residues
1996
Equilibrium thermodynamics of homopolymers and clusters: Molecular dynamics and Monte Carlo simulations of systems with square-well interactions
1997
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings
2011 StandoutNobel
First-Order Disorder-to-Order Transition in an Isolated Homopolymer Model
1996
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Probing the role of packing specificity in protein design
1997
Quantum Mechanical Continuum Solvation Models
2005 Standout
Protein topology and stability define the space of allowed sequences
2002 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Tryptophan zippers: Stable, monomeric β-hairpins
2001
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
Femtosecond dynamics of DNA-mediated electron transfer
1999 StandoutNobel
Clustering of low-energy conformations near the native structures of small proteins
1998 StandoutNobel
Limited internal friction in the rate-limiting step of a two-state protein folding reaction
1998 StandoutNobel
Works of John Orban being referenced
NMR structures of two designed proteins with high sequence identity but different fold and function
2008
A minimal sequence code for switching protein structure and function
2009
The design and characterization of two proteins with 88% sequence identity but different structure and function
2007
Hydrogen-Deuterium Exchange in the Free and Immunoglobulin G-Bound Protein G B-Domain
1994
Mutational Tipping Points for Switching Protein Folds and Functions
2012
Thermodynamic analysis of the folding of the streptococcal protein G IgG-binding domains B1 and B2: why small proteins tend to have high denaturation temperatures
1992
NMR structure of HI0004, a putative essential gene product from Haemophilus influenzae, and comparison with the X‐ray structure of an Aquifex aeolicus homolog
2005
Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G
1992
A solid-state deuterium NMR investigation of conformation and order in magnetically oriented [d(CGCGAATTCGCG)]2
1990
Assessment of Stability Differences in the Protein G B1 and B2 Domains From Hydrogen-Deuterium Exchange: Comparison with Calorimetric Data
1995
1H NMR Assignments and Conformational Analysis of the Oligoribonucleotides CA, CAU, CAUG, ACAUG, and UCAUG: Observation of Pyrimidine H5-H1′ Long-Range Scalar Couplings
1990
Errors in RNA NOESY distance measurements in chimeric and hybrid duplexes: differences in RNA and DNA proton relaxation
1992
Sequence-specific proton NMR assignments and secondary structure of the streptococcal protein G B2-domain
1992
A solid-state deuterium NMR study of furanose ring dynamics in [d(CGCGAATTCGCG)]2
1990
Preparation of -butyldimethylsilyl (tbdms) enol ethers using potassium hydride in the presence of tbdms chloride
1984
Structure and Dynamics of an Acid-Denatured Protein G Mutant
2000
Solution NMR Structures of IgG Binding Domains with Artificially Evolved High Levels of Sequence Identity but Different Folds,
2005
Peptidoglycan Recognition by Pal, an Outer Membrane Lipoprotein,
2006
Directed Evolution of Highly Homologous Proteins with Different Folds by Phage Display: Implications for the Protein Folding Code
2005
Molecular dynamics of rigid and non-rigid necklaces of hard discs
1980