Citation Impact
Citing Papers
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy
2009
Critical determinants of metastasis
2002
Induction of Vascular Endothelial Growth Factor by Insulin-like Growth Factor 1 in Colorectal Carcinoma
1996
Inflammation and cancer
2002 StandoutNature
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression
2009
Histone deacetylases and cancer
2007
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Molecular biology of the Ets family of transcription factors
2003
Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization
2001
Oncogenic kinase signalling
2001 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
2009 StandoutNature
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Adhesion molecules in cancer: the role of integrins
1993
Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways
1998
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
2010 StandoutNature
c-Myc Blazing a Trail of Death: Coupling of the Mitochondrial and Death Receptor Apoptosis Pathways by c-Myc
2007
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Strategies for MMP inhibition in cancer: innovations for the post-trial era
2002
The Hallmarks of Cancer
2000 Standout
Integrins and cancer
1996
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
2011 StandoutNature
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Cardiac Myocyte Cell Cycle Control in Development, Disease, and Regeneration
2007
Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence
2008
Expression of Integrin αVβ3 in Pancreatic Carcinoma: Relation to MMP-2 Activation and Lymph Node Metastasis
2002
Regulation of the INK4b–ARF–INK4a tumour suppressor locus: all for one or one for all
2006
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Integrative analysis of RUNX1 downstream pathways and target genes
2008
The microenvironment of the tumour–host interface
2001 StandoutNature
A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
1996
Intrinsic tumour suppression
2004 Nature
Chromatin Modification, Leukaemia and Implications for Therapy
2002
Adenoviral Gene Transfer of β3 Integrin Subunit Induces Conversion from Radial to Vertical Growth Phase in Primary Human Melanoma
1998
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Reflecting on 25 years with MYC
2008 Standout
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo.
1997
Leukaemogenesis: more than mutant genes
2009
The opposing roles of laminin-binding integrins in cancer
2016
Mechanisms of Bone Metastasis
2004 Standout
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis
2003
Wnt signalling in stem cells and cancer
2005 StandoutNature
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
A tumor suppressor role for PP2A-B56α through negative regulation of c-Myc and other key oncoproteins
2008
Neoplastic development in plasma cells
2003
The Oscar-worthy role of Myc in apoptosis
2006
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
1995 StandoutNature
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
E2F1 and c-Myc Potentiate Apoptosis through Inhibition of NF-κB Activity that Facilitates MnSOD-Mediated ROS Elimination
2002
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells
2004
Homeobox D10 Induces Phenotypic Reversion of Breast Tumor Cells in a Three-Dimensional Culture Model
2005
Death Receptors: Signaling and Modulation
1998 StandoutScience
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
1994
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Transient Regenerative Potential of the Neonatal Mouse Heart
2011 StandoutScience
pVHL 19 is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation
1998 StandoutNobel
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction.
1997
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
c-Myc Augments Gamma Irradiation-Induced Apoptosis by Suppressing Bcl-XL
2003
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
The INK4a/ARF locus and melanoma
2003
Caspases: Enemies Within
1998 StandoutScience
A Matter of Life and Cell Death
1998 Science
Works of John Nip being referenced
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1
2001
Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells.
1995
The t(8;21) fusion protein, AML1–ETO, specifically represses the transcription of the p14ARF tumor suppressor in acute myeloid leukemia
2002
Integrin α3β1 can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma
1996
The role of the integrin vitronectin receptor, ?v?3 in melanoma metastasis
1995
Expression of the AML-1 Oncogene Shortens the G1Phase of the Cell Cycle
2000
Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin.
1992
E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation
2001
TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of stromelysin-1
2000
E2F-1 Cooperates with Topoisomerase II Inhibition and DNA Damage To Selectively Augment p53-Independent Apoptosis
1997
E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation.
1998
Paracrine growth stimulation by hepatocyte-derived insulin-like growth factor-1: a regulatory mechanism for carcinoma cells metastatic to the liver.
1994
ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain
2001