John Michael Ong’echa

Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine

Trained immunity: A program of innate immune memory in health and disease

Pure Hemozoin Is Inflammatory In Vivo and Activates the NALP3 Inflammasome via Release of Uric Acid

Patent Filarial Infection Modulates Malaria-Specific Type 1 Cytokine Responses in an IL-10-Dependent Manner in a Filaria/Malaria-Coinfected Population

IL-10: The Master Regulator of Immunity to Infection

Platelet factor 4–induced T _H 1-T _reg polarization suppresses antitumor immunity

Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

Determining Important Parameters in the Spread of Malaria Through the Sensitivity Analysis of a Mathematical Model

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Lethal Malaria: Marchiafava and Bignami Were Right

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

Lymphatic filariasis and onchocerciasis

Pattern Recognition Receptors and Inflammation

Development, expression, and murine testing of a multistage Plasmodium falciparum malaria vaccine candidate

Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

Malaria

Pre-erythrocytic malaria vaccines: towards greater efficacy

Monocytes and macrophages in malaria: protection or pathology?

Innate sensing of malaria parasites

Hidradenitis suppurativa

The Inflammasomes

Malaria-Induced NLRP12/NLRP3-Dependent Caspase-1 Activation Mediates Inflammation and Hypersensitivity to Bacterial Superinfection

Defining trained immunity and its role in health and disease

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

CXCR3 ligands in disease and therapy

Diagnosis, Clinical Presentation, and In-Hospital Mortality of Severe Malaria in HIV-Coinfected Children and Adults in Mozambique

Toll-Like Receptor Signaling Pathways

Interferon-γ: The Jekyll and Hyde of Malaria

How many child deaths can we prevent this year?

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology

Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics.

2016 Infectious Diseases Society of America (IDSA) Clinical Practice Guideline for the Treatment of Coccidioidomycosis

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden

Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal

Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality

IMPLICATIONS OF THE WESTERN KENYA PERMETHRIN-TREATED BED NET STUDY FOR POLICY, PROGRAM IMPLEMENTATION, AND FUTURE RESEARCH

Insecticide-treated bed nets and curtains for preventing malaria

Inflammatory responses and inflammation-associated diseases in organs

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

Platelet Induction of the Acute-Phase Response Is Protective in Murine Experimental Cerebral Malaria

IMPACT OF PERMETHRIN-TREATED BED NETS ON MALARIA, ANEMIA, AND GROWTH IN INFANTS IN AN AREA OF INTENSE PERENNIAL MALARIA TRANSMISSION IN WESTERN KENYA

Macrophage plasticity, polarization, and function in health and disease

Reduced interferon (IFN)-α conditioned by IFNA2 (−173) and IFNA8 (−884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality

Increased severe anemia in HIV-1-exposed and HIV-1-positive infants and children during acute malaria

Hematological predictors of increased severe anemia in Kenyan children coinfected with Plasmodium falciparum and HIV‐1

Cytotoxic T cell reactivity and HLA‐B35 binding of the variant Plasmodium falciparum circumsporozoite protein CD8⁺ CTL epitope in naturally exposed Kenyan adults

Severe Malarial Anemia: Innate Immunity and Pathogenesis

Relationship between inflammatory mediator patterns and anemia in HIV‐1 positive and exposed children with Plasmodium falciparum malaria

Polymorphic Variability in the Interleukin (IL)–1β Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL‐1β Production

Acquisition of Hemozoin by Monocytes Down-Regulates Interleukin-12 p40 (IL-12p40) Transcripts and Circulating IL-12p70 through an IL-10-Dependent Mechanism: In Vivo and In Vitro Findings in Severe Malarial Anemia

ASSOCIATION OF INTERFERON-γ RESPONSES TO PRE-ERYTHROCYTIC STAGE VACCINE CANDIDATE ANTIGENS OF PLASMODIUM FALCIPARUM IN YOUNG KENYAN CHILDREN WITH IMPROVED HEMOGLOBIN LEVELS: XV. ASEMBO BAY COHORT PROJECT

Increased circulating interleukin (IL)-23 in children with malarial anemia: In vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10

Role of Monocyte-Acquired Hemozoin in Suppression of Macrophage Migration Inhibitory Factor in Children with Severe Malarial Anemia

Bacteremia in Kenyan Children Presenting with Malaria

EFFECTS OF PERMETHRIN-TREATED BED NETS ON IMMUNITY TO MALARIA IN WESTERN KENYA II. ANTIBODY RESPONSES IN YOUNG CHILDREN IN AN AREA OF INTENSE MALARIA TRANSMISSION