Citation Impact
Citing Papers
Salmonella Promoters Preferentially Activated Inside Tumors
2008
Optimized Clostridium -Directed Enzyme Prodrug Therapy Improves the Antitumor Activity of the Novel DNA Cross-Linking Agent PR-104
2008
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Inducible System in Human Hepatoma Cell Lines for Hepatitis C Virus Production
2002 StandoutNobel
Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication
2018 StandoutNobel
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
Non-invasive 19F MR spectroscopy of 5-fluorocytosine to 5-fluorouracil conversion by recombinant Salmonella in tumours
2003
Microbiota in health and diseases
2022 Standout
Efficacy of gene therapy-delivered cytosine deaminase is determined by enzymatic activity but not expression
2007
Bio-inspired, bioengineered and biomimetic drug delivery carriers
2011
A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas
2008
Attenuated Bacteria as Effectors in Cancer Immunotherapy
2008
Inhibition of Tumor Growth Using Salmonella Expressing Fas Ligand
2008
Nucleoside Analog Inhibitors of Hepatitis C Virus Replication
2006
In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit
2007
Clostridia in cancer therapy
2003
Systemic administration of attenuated Salmonella choleraesuis carrying thrombospondin-1 gene leads to tumor-specific transgene expression, delayed tumor growth and prolonged survival in the murine melanoma model
2004
3-Hydroxypropionaldehyde: applications and perspectives of biotechnological production
2004
Oral delivery of tumor‐targeting Salmonella exhibits promising therapeutic efficacy and low toxicity
2009
Tumor-targeting amino acid auxotrophic Salmonella typhimurium
2009
Drug penetration in solid tumours
2006 Standout
Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics
2010 StandoutNobel
Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice
2009
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Copper in diseases and treatments, and copper‐based anticancer strategies
2009
Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth
2008
Engineering the perfect (bacterial) cancer therapy
2010 Standout
Environmentally Controlled Invasion of Cancer Cells by Engineered Bacteria
2005
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients
2003
Systemic administration of attenuated Salmonella choleraesuis in combination with cisplatin for cancer therapy
2005
Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice
2007
Cytotoxicity in human cancer cells and mitochondrial dysfunction induced by a series of new copper(I) complexes containing tris(2-cyanoethyl)phosphines
2010
The 1.14 Å Crystal Structure of Yeast Cytosine Deaminase
2003
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of l-arabinose as inducer of bacterial gene expression in vivo
2007
Oral delivery of tumor‐targeting Salmonella for cancer therapy in murine tumor models
2007
Short hairpin RNA–expressing bacteria elicit RNA interference in mammals
2006
Use of bacteria in anti‐cancer therapies
2005
Modulation of host metabolism as a target of new antivirals
2007
Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimurium
2009
Translation of new cancer treatments from pet dogs to humans
2008 Standout
Sofosbuvir Inhibits Hepatitis E Virus Replication In Vitro and Results in an Additive Effect When Combined With Ribavirin
2015 StandoutNobel
Carboxypeptidase G2-based gene-directed enzyme–prodrug therapy: a new weapon in the GDEPT armoury
2007
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
2010 Standout
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Targeted therapy of spinal cord glioma with a genetically modified Salmonella typhimurium
2009
Designing hydrogels for controlled drug delivery
2016 Standout
Tumor Invasion of Salmonella enterica Serovar Typhimurium Is Accompanied by Strong Hemorrhage Promoted by TNF-α
2009
Identifying Small Molecules via High Resolution Mass Spectrometry: Communicating Confidence
2014 Standout
Endostatin gene therapy delivered by Salmonella choleraesuis in murine tumor models
2004
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
Bacteria in gene therapy: bactofection versus alternative gene therapy
2005
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro
2006
IL-18-producing Salmonella inhibit tumor growth
2008
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Suicide gene/prodrug therapy using salmonella‐mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6‐methoxypurine 2′‐deoxyriboside in murine mammary carcinoma 4T1 model
2008
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors
2009
Copper Complexes as Anticancer Agents
2009
Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases
2013
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
The way forward in HCV treatment — finding the right path
2007 StandoutNobel
Positron emission tomography (PET) imaging of tumor-localized Salmonella expressing HSV1-TK
2004
Drug Resistance and the Solid Tumor Microenvironment
2007 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Emerging Frontiers in Drug Delivery
2016
Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer
2007
Chemistry of Polyvalent Iodine
2008 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Helicase Inhibitors as Specifically Targeted Antiviral Therapy for Hepatitis c
2009
Targeted Therapy with aSalmonella TyphimuriumLeucine-Arginine Auxotroph Cures Orthotopic Human Breast Tumors in Nude Mice
2006
Implications of Rewiring Bacterial Quorum Sensing
2007 StandoutNobel
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium
2005
Attenuated Salmonella Targets Prodrug Activating Enzyme Carboxypeptidase G2 to Mouse Melanoma and Human Breast and Colon Carcinomas for Effective Suicide Gene Therapy
2008
Cell-Based and Animal Models for Hepatitis B and C Viruses
1999
Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains
2012
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
An Efficient and Diastereoselective Synthesis of PSI-6130: A Clinically Efficacious Inhibitor of HCV NS5B Polymerase
2009
Novel di-2-pyridyl–derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment
2004
Technology development for the production of biobased products from biorefinery carbohydrates—the US Department of Energy’s “Top 10” revisited
2010 Standout
Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors.
2003
Engineering microbial consortia: a new frontier in synthetic biology
2008 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
AttenuatedSalmonellaengineered to produce human cytokine LIGHT inhibit tumor growth
2007
Antitumour activity of Salmonella typhimurium VNP20047 in B16(F10) murine melanoma model.
2004
Response of Hepatitis C Virus to Long-Term Passage in the Presence of Alpha Interferon: Multiple Mutations and a Common Phenotype
2013 StandoutNobel
Recent advances in the synthesis of fluorinated nucleosides
2009
Engineering Nanoparticle-Coated Bacteria as Oral DNA Vaccines for Cancer Immunotherapy
2015
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Development of novel treatments for hepatitis C
2009
Discovery of Daclatasvir, a Pan-Genotypic Hepatitis C Virus NS5A Replication Complex Inhibitor with Potent Clinical Effect
2014
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Analysis of nanoparticle delivery to tumours
2016 Standout
Fluorinations of α‐Seleno Carboxylic Acid Derivatives with Hypervalent (Difluoroiodo)toluene
2005
Discovery of a β-d -2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
2010
Internal Disequilibria and Phenotypic Diversification during Replication of Hepatitis C Virus in a Noncoevolving Cellular Environment
2017 StandoutNobel
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Antitumor effects in mice of the intravenous injection of attenuated Salmonella typhimurium.
2002
Single‐molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase
2017 StandoutNobel
Escherichia coli Nissle 1917 Facilitates Tumor Detection by Positron Emission Tomography and Optical Imaging
2008
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
Emerging Droplet Microfluidics
2017 Standout
Chelators at the Cancer Coalface: Desferrioxamine to Triapine and Beyond
2006
Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity
2006
Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus
2016 StandoutNobel
Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants
2009 StandoutNobel
Systemic Administration of an Attenuated, Tumor-TargetingSalmonella typhimuriumto Dogs with Spontaneous Neoplasia: Phase I Evaluation
2005
Biotransformation of the Antiviral Drugs Acyclovir and Penciclovir in Activated Sludge Treatment
2011
Works of John Mao being referenced
Phase I Study of the Intravenous Administration of AttenuatedSalmonella typhimuriumto Patients With Metastatic Melanoma
2002
Synthesis and biological evaluation of a series of 2′-fluorinated-2′,3′-dideoxy-2′,3′-didehydro-(l)-nucleosides
1998
Phase I and pharmacokinetic study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) using a single intravenous dose schedule
2002
Tumor-Targeted Salmonella Expressing Cytosine Deaminase as an Anticancer Agent
2002
Metabolic Fate of [14C]Acrolein under Aerobic and Anaerobic Aquatic Conditions
1995
Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine
2006
Separation of Acrolein and Its Possible Metabolites Using Different Modes of High Performance Liquid Chromatography
1994