Citation Impact
Citing Papers
Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes
2015 Standout
Genetic-related and carbohydrate-related factors affecting liver fat accumulation
2012
gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission
2007 StandoutNobel
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Adipocyte-specific Disruption of Fat-specific Protein 27 Causes Hepatosteatosis and Insulin Resistance in High-fat Diet-fed Mice
2014
Non-alcoholic fatty liver and the gut microbiota
2016
Depression
2018 Standout
Genetic determinants of hepatic steatosis in man
2011
Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
2014
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection
2000
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
2010
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
2013
Adipose tissue browning and metabolic health
2013
Genetic Predisposition in NAFLD and NASH: Impact on Severity of Liver Disease and Response to Treatment
2013
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Genetic modifiers of non-alcoholic fatty liver disease progression
2011
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Pharmacological and nutritional agents promoting browning of white adipose tissue
2012
The Effect of PNPLA3 on Fibrosis Progression and Development of Hepatocellular Carcinoma: A Meta-analysis
2014
PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
2012
Functions of autophagy in normal and diseased liver
2013
The Outcome of Hepatitis C Virus Infection Is Predicted by Escape Mutations in Epitopes Targeted by Cytotoxic T Lymphocytes
2001 StandoutNobel
Hepatic Fat Accumulation Is Modulated by the Interaction between the rs738409 Variant in the PNPLA3 Gene and the Dietary Omega6/Omega3 PUFA Intake
2012
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis
2011
Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats
2010
Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissue in Vivo
2011
Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes
2014
Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells
2010
Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef
1999
Dissociating fatty liver and diabetes
2012
Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
2015
Prevalence and Severity of Nonalcoholic Fatty Liver Disease in Non-Obese Patients: A Population Study Using Proton-Magnetic Resonance Spectroscopy
2015
Adipocyte lipases and lipid droplet-associated proteins: insight from transgenic mouse models
2011
Mechanisms and disease consequences of nonalcoholic fatty liver disease
2021
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
2017
NAFLD and diabetes mellitus
2016
Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein
2010
Genetic predisposition in nonalcoholic fatty liver disease
2017
The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population
2011
A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy
2017
Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
2010
Control of a Mucosal Challenge and Prevention of AIDS by a Multiprotein DNA/MVA Vaccine
2001 StandoutScience
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
2017
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
2016 Standout
Patatin-Like Phospholipase Domain-Containing 3/Adiponutrin Deficiency in Mice Is Not Associated with Fatty Liver Disease†,‡
2010
Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans
2012
Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors
2014
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The Association of Genetic Variability in Patatin-Like Phospholipase Domain-Containing Protein 3 (PNPLA3) with Histological Severity of Nonalcoholic Fatty Liver Disease†
2010
Non-alcoholic fatty liver disease
2021 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
2014
Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
2011
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
2013
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes
2010
Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol
2011
Therapeutic Landscape for NAFLD in 2020
2020
Adaptive thermogenesis in adipocytes: Is beige the new brown?
2013
Animal models of nonalcoholic fatty liver disease
2010
A Common Variant in the Patatin-Like Phospholipase 3 Gene ( PNPLA3 ) Is Associated with Fatty Liver Disease in Obese Children and Adolescents
2010
Loss of Mitogen-activated Protein Kinase Phosphatase-1 Protects from Hepatic Steatosis by Repression of Cell Death-inducing DNA Fragmentation Factor A (DFFA)-like Effector C (CIDEC)/Fat-specific Protein 27
2011
Virion Assembly and Release
2013
Toward Genetic Prediction of Nonalcoholic Fatty Liver Disease Trajectories: PNPLA3 and Beyond
2020
NAFLD in Asia—as common and important as in the West
2013
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Advances in Pediatric Nonalcoholic Fatty Liver Disease†
2009
Lipid-induced insulin resistance: unravelling the mechanism
2010
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals
2017
Role of adipose specific lipid droplet proteins in maintaining whole body energy homeostasis
2013
Past, present and future perspectives in nonalcoholic fatty liver disease
2019
Ror‐family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
2009
PNPLA3 Variants Specifically Confer Increased Risk for Histologic Nonalcoholic Fatty Liver Disease But Not Metabolic Disease†,‡
2010
Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome
2014
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese
2012
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
2015
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Hepatocellular carcinoma
2022 Standout
The neurobiology of depression and antidepressant action
2012
Characterization of the Peptide Binding Motif of a Rhesus MHC Class I Molecule (Mamu-A*01) That Binds an Immunodominant CTL Epitope from Simian Immunodeficiency Virus
1998
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
2004 StandoutNobel
gp340 Promotes Transcytosis of Human Immunodeficiency Virus Type 1 in Genital Tract-Derived Cell Lines and Primary Endocervical Tissue
2009 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
GRK2 contribution to the regulation of energy expenditure and brown fat function
2012
Sex differences in non-alcoholic fatty liver disease: hints for future management of the disease
2020
Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization
2010
Genetic Pathways in Nonalcoholic Fatty Liver Disease: Insights From Systems Biology
2020
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum
2016
Lumenal Lipid Metabolism
2012
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
High Levels of Viral Replication during Primary Simian Immunodeficiency Virus SIVagm Infection Are Rapidly and Strongly Controlled in African Green Monkeys
2000 StandoutNobel
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD
2020
A Functional Interaction between RIP140 and PGC-1α Regulates the Expression of the Lipid Droplet Protein CIDEA
2008
Comparison of Immunity Generated by Nucleic Acid-, MF59-, and ISCOM-Formulated Human Immunodeficiency Virus Type 1 Vaccines in Rhesus Macaques: Evidence for Viral Clearance
1999
Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes
2012
Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers
2013 StandoutNobel
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells
2017
Towards an integrated view of Wnt signaling in development
2009
Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high‐fat‐diet‐induced obesity
2012
The rs2294918 E434K variant modulates patatin‐like phospholipase domain‐containing 3 expression and liver damage
2015
High Levels of Viral Replication Contrast with Only Transient Changes in CD4+and CD8+Cell Numbers during the Early Phase of Experimental Infection with Simian Immunodeficiency Virus SIVmnd-1 inMandrillus sphinx
2002 StandoutNobel
Intracellular Trafficking and Secretion of VLDL
2012
Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice
2016
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Immunoglobulin G (IgG) and IgA, but also Nonantibody Factors, Account for In Vitro Neutralization of Human Immunodeficiency Virus (HIV) Type 1 Primary Isolates by Serum and Plasma of HIV-Infected Patients
2001 StandoutNobel
Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function
2014 StandoutNobel
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
2020
Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
2010
Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
2010
PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice
2019
Review article: the emerging role of genetics in precision medicine for patients with non‐alcoholic steatohepatitis
2020
Mucosal Transmission and Induction of Simian AIDS by CCR5-Specific Simian/Human Immunodeficiency Virus SHIV SF162P3
2001
Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein
2013 StandoutNobel
Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys
1997
The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation
2017
Nonalcoholic Fatty Liver Disease
2015 Standout
The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function
2011
The Simian Immunodeficiency Virus ΔnefVaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4+T Cells and Elicits a Local Perforin-Positive CD8+T-Cell Response
2002 StandoutNobel
Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability
2011
A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques
1998
Emerging Role of Genomic Analysis in Clinical Evaluation of Lean Individuals With NAFLD
2021
Impact of Viral Factors on Very Early In Vivo Replication Profiles in Simian Immunodeficiency Virus SIVagm-Infected African Green Monkeys
2005 StandoutNobel
Characterization of Hepatitis C Virus Core-Specific Immune Responses Primed in Rhesus Macaques by a Nonclassical ISCOM Vaccine
2001 StandoutNobel
The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
2016
Works of John Li being referenced
Cideb controls sterol‐regulated ER export of SREBP / SCAP by promoting cargo loading at ER exit sites
2019
Abnormal resting state corticolimbic blood flow in depressed unmedicated patients with major depression: A 15O‐H2O PET study
2011
Human Immunodeficiency Virus Type 1 Envelope Glycoprotein-Specific Cytotoxic T Lymphocytes in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys
1995
Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis
2012
A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
2009
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome
2010
Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2
2008
Utility of SHIV for Testing HIV-1 Vaccine Candidates in Macaques
1996
Downregulation of AMP‐activated protein kinase by Cidea‐mediated ubiquitination and degradation in brown adipose tissue
2008
Up-Regulation of Mitochondrial Activity and Acquirement of Brown Adipose Tissue-Like Property in the White Adipose Tissue of Fsp27 Deficient Mice
2008
Cideb, an ER- and Lipid Droplet-Associated Protein, Mediates VLDL Lipidation and Maturation by Interacting with Apolipoprotein B
2009
A feed-forward loop amplifies nutritional regulation of PNPLA3
2010
Cideb Regulates Diet-Induced Obesity, Liver Steatosis, and Insulin Sensitivity by Controlling Lipogenesis and Fatty Acid Oxidation
2007
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
2014