Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization
2009
Biologically active dihydropyrimidones of the Biginelli-type — a literature survey
2000 Standout
Subtypes of functional α1- and α2-adrenoceptors
1998
Contribution of α2 receptor subtypes to nerve injury‐induced pain and its regulation by dexmedetomidine
2001
Transgenic models of α2-adrenergic receptor subtype function
2008
NeuPSIG guidelines on neuropathic pain assessment
2010 Standout
Recent advances in selective α1-adrenoreceptor antagonists as antihypertensive agents
2008
Neural mechanism underlying acupuncture analgesia
2008 Standout
The N Terminus of the Human α1D-Adrenergic Receptor Prevents Cell Surface Expression
2004
Pharmacological evidence for the role of central alpha 1B-adrenoceptors in the motor activity and spontaneous movement of mice
2001
Respective contributions of α‐adrenergic and non‐adrenergic mechanisms in the hypotensive effect of imidazoline‐like drugs
2001
Descending control of pain
2002 Standout
Loss of activation of Gs but not Gi following expression of an α2A‐adrenoceptor‐Gi1α fusion protein
1998
Modulation of Relative Intrinsic Activity of Agonists at theAlpha-2A Adrenoceptor by Mutation of Residue 351 of G Protein Gi1α
1999
α1‐, α2‐ and β‐adrenoceptors in the urinary bladder, urethra and prostate
2006
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Quantifying Ligand Bias at Seven-Transmembrane Receptors
2011 StandoutNobel
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels
2009 StandoutNobel
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Quantification of Functional Selectivity at the Human α1A-Adrenoceptor
2010
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
GPCR–Gα fusion proteins: molecular analysis of receptor–G-protein coupling
1999 StandoutNobel
Recognition of Conserved Amino Acid Motifs of Common Viruses and Its Role in Autoimmunity
2005 StandoutNobel
Agonist trafficking of Gi/o‐mediated α2A‐adrenoceptor responses in HEL 92.1.7 cells
2001
The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor
2003 Standout
Mouse β3a‐ and β3b‐adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways
2002
Systemic sclerosis: a prototypic multisystem fibrotic disorder
2007 Standout
Regulation of G-Protein Coupled Receptor Traffic by an Evolutionary Conserved Hydrophobic Signal
2010 StandoutNobel
The vasculopathy of Raynaud's phenomenon and scleroderma
2003
High-affinity binding of β-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: Norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain
2005
Behavioral and neurochemical characterization of α2A-adrenergic receptor knockout mice
2002 StandoutNobel
EAU Guidelines on the Treatment and Follow-up of Non-neurogenic Male Lower Urinary Tract Symptoms Including Benign Prostatic Obstruction
2013 Standout
Major Depressive Disorder
2008 Standout
β-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)
2009 Standout
Acute Agonist-mediated Desensitization of the Human α1a-Adrenergic Receptor Is Primarily Independent of Carboxyl Terminus Regulation
2002
Kinase inhibitors: the road ahead
2018
Biological significance of agmatine, an endogenous ligand at imidazoline binding sites
2001
From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease
2010
In Vivo Gene Modification Elucidates Subtype-Specific Functions of α2-Adrenergic Receptors
2000
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
alpha2A-adrenoceptor stimulation reduces capsaicin-induced glutamate release from spinal cord synaptosomes.
2001
Vascular Adrenoceptors: An Update
2001
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Design and Synthesis of Novel α1a Adrenoceptor-Selective Antagonists. 4. Structure−Activity Relationship in the Dihydropyrimidine Series
1999
Pharmacology of Penile Erection
2001
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
2013
Functional Differences between Full and Partial Agonists: Evidence for Ligand-Specific Receptor Conformations
2001 StandoutNobel
BindingDB Entry 5280: S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine.
2012
In vivo gene modification elucidates subtype-specific functions of alpha(2)-adrenergic receptors.
2000
Biomedical Importance of Indoles
2013 Standout
Microglial M1/M2 polarization and metabolic states
2015 Standout
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
2000 Standout
Insights into ligand pharmacology using receptor–G-protein fusion proteins
2000
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Works of John Lesnick being referenced
RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification.
1996
Molecular cloning, genomic characterization and expression of novel human α1A‐adrenoceptor isoforms
1998
Human cloned α1A-adrenoceptor isoforms display α1L-adrenoceptor pharmacology in functional studies
1999
Pharmacological pleiotropism of the human recombinant α1A‐adrenoceptor: implications for α1‐adrenoceptor classification
1997
Cardiovascular effects of rilmenidine, moxonidine and clonidine in conscious wild‐type and D79N α2A‐adrenoceptor transgenic mice
1999
Ligand Efficacy and Potency at Recombinant α2 Adrenergic Receptors
1998
Imidazoline-Binding Domains on Monoamine Oxidase B and Subpopulations of Enzyme
2000
Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR
2016