Citation Impact
Citing Papers
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Video-Rate Far-Field Optical Nanoscopy Dissects Synaptic Vesicle Movement
2008 StandoutScienceNobel
Infectious enveloped RNA virus antigenic chimeras.
1992 StandoutNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Distribution of acceptors for ß-bungarotoxin in the central nervous system of the rat
1988
A Transgenic Mouse Model of Inducible Macrophage Depletion
2009
Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment
1993 Standout
pH‐dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen
1993
Ribosome-inactivating proteins from plants
1993
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
1995
Differences in the multiple step process of inhibition of neurotransmitter release induced by tetanus toxin and botulinum neurotoxins type A and B atAplysia synapses
1996
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
1993 StandoutNature
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Interaction of tetanus toxin with lipid vesicles. Effects of pH, surface charge, and transmembrane potential on the kinetics of channel formation
1989
Bacterial protein toxins penetrate cells via a four‐step mechanism
1994
IgA Protease from Neisseria gonorrhoeae Inhibits Exocytosis in Bovine Chromaffin Cells Like Tetanus Toxin
1995
Staphylococcal and Streptococcal Pyrogenic Toxins Involved in Toxic Shock Syndrome and Related Illnesses
1990
Epidermal Growth Factor (EGF) Receptor-dependent ERK Activation by G Protein-coupled Receptors
2001 StandoutNobel
Mechanism of action of tetanus and botulinum neurotoxins
1994
Binding and Transcytosis of Botulinum Neurotoxin by Polarized Human Colon Carcinoma Cells
1998
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner
2009 Standout
Selective Interaction of Complexin with the Neuronal SNARE Complex
2000 StandoutNobel
The N‐terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayers
1987
Identification of an ion channel‐forming motif in the primary structure of tetanus and botulinum neurotoxins
1992
A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration
2005
Regulation of LNS Domain Function by Alternative Splicing: The Structure of the Ligand-Binding Domain of Neurexin Iβ
1999 StandoutNobel
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
1997
Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain
1994
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen
1998 Standout
Structure and function of tetanus and botulinum neurotoxins
1995
Superantigens: Mechanism of T-Cell Stimulation and Role in Immune Responses
1991
Neurospecific Binding, Internalization, and Retrograde Axonal Transport
1995
Direct visualization of botulinum neurotoxin-induced channels in phospholipid vesicles
1993 Nature
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Structural homology between virulence-associated bacterial adenylate cyclases
1988
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors
1996 Standout
Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein
1988 Nature
Molecular mechanisms of action of bacterial protein toxins
1994
Action of diphtheria toxin does not depend on the induction of large, stable pores across biological membranes
1990
Point Mutations in Anthrax Protective Antigen That Block Translocation
2001
Staphylococcus aureusInfections
1998 Standout
Gene regulation by steroid hormones
1989 Standout
Phospholipase A2—a structural review
1996
Adsorptive endocytosis of Semliki Forest virus
1980
The Staphylococcal Enterotoxins and Their Relatives
1990 StandoutScience
Minimal essential domains specifying toxicity of the light chains of tetanus toxin and botulinum neurotoxin type A.
1992
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Phospholipases in snake venoms and their effects on nerve and muscle
1985
Evidence for direct binding of Clostridium botulinum type E derivative toxin and its fragments to gangliosides and free fatty acids
1986
Primary structure and expression of a functional human glucocorticoid receptor cDNA
1985 StandoutNature
Characterization of the binding and internalization of tetanus toxin in a neuroblastoma hybrid cell line
1986
Tetanus toxin induces fusion and aggregation of lipid vesicles containing phosphatidylinositol at low pH
1985
Synaptobrevin/vesicle-associated membrane protein (VAMP) of Aplysia californica: structure and proteolysis by tetanus toxin and botulinal neurotoxins type D and F.
1994 StandoutNobel
Pasteurella multocida toxin, a potent mitogen, stimulates protein kinase C-dependent and -independent protein phosphorylation in Swiss 3T3 cells.
1990
A 50‐kDa fragment from the NH2‐terminus of the heavy subunit of Clostridium botulinum type A neurotoxin forms channels in lipid vesicles
1987
An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes
2008
Steroid Hormone Receptors
1976
Infection by verocytotoxin-producing Escherichia coli
1989
Structure and Function of Lipopolysaccharide Binding Protein
1990 StandoutScience
The Steroid and Thyroid Hormone Receptor Superfamily
1988 StandoutScience
Microsomal and cytosolic fractions of guinea pig hepatocytes contain 100-kilodalton GTP-binding proteins reactive with antisera against alpha subunits of stimulatory and inhibitory heterotrimeric GTP-binding proteins.
1990 StandoutNobel
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.
1988
The calmodulin‐sensitive adenylate cyclase of Bordetella pertussis: cloning and expression in Escherichia col
1988
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A.
1992
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations.
1988
Expression and characterization of calmodulin-activated (type I) adenylylcyclase
1991 StandoutNobel
A model of anthrax toxin lethal factor bound to protective antigen
2005 StandoutNobel
Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.
1985
Endocytosis and the recycling of plasma membrane.
1983 StandoutNobel
A significant lag in the induction of ovalbumin messenger RNA by steroid hormones: A receptor translocation hypothesis
1976
Adenovirus-induced release of epidermal growth factor and pseudomonas toxin into the cytosol of KB cells during receptor-mediated endocytosis
1983
Complete amino acid sequence of staphylococcal enterotoxin A.
1987
Membrane Fusion and Exocytosis
1999 StandoutNobel
Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.
1982
Molecular cloning of the gene encoding the mosaic neurotoxin, composed of parts of botulinum neurotoxin types C1 and D, and PCR detection of this gene from Clostridium botulinum type C organisms
1996
Cloning of the cDNA of a Human Neutrophil Bactericidal Protein
1989
Inhibition of Transmitter Release Correlates with the Proteolytic Activity of Tetanus Toxin and Botulinus Toxin A in Individual Cultured Synapses ofHirudo medicinalis
1997
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA.
1977 StandoutNobel
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
1988
[31] Diphtheria toxin: Quantification and assay
1988
Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes
2012
Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization
1984 Nature
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses
1997 StandoutNobel
Effect of pH on the interaction of botulinum neurotoxins A, B and E with liposomes
1989
Base substitutions, length differences and DNA strand asymmetries in the human Gγ and Aγ fetal globin gene region
1981 StandoutNobel
Assembly of SNARE Core Complexes Prior to Neurotransmitter Release Sets the Readily Releasable Pool of Synaptic Vesicles
2000 StandoutNobel
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis.
1986
Evidence for synthesis of scrapie prion proteins in the endocytic pathway.
1992 StandoutNobel
Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol.
1993
Insertion of diphtheria toxin into and across membranes: role of phosphoinositide asymmetry
1982 Nature
A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome.
1993 StandoutNobel
Characterization of the channel properties of tetanus toxin in planar lipid bilayers
1988
Immunotoxins
1986
Diphtheria Toxin Binds to the Epidermal Growth Factor (EGF)-like Domain of Human Heparin-binding EGF-like Growth Factor/Diphtheria Toxin Receptor and Inhibits Specifically Its Mitogenic Activity
1995
Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
1983 StandoutNobel
The presence of ovalbumin mRNA coding sequences in multiple restriction fragments of chicken DNA
1977 StandoutNobel
Receptor-mediated endocytosis.
1986
Inhibition of transmitter release correlates with the proteolytic activity of tetanus toxin and botulinus toxin A in individual cultured synapses of Hirudo medicinalis.
1997
Three-Dimensional Structure of Cholera Toxin Penetrating a Lipid Membrane
1988 StandoutScienceNobel
Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin
1988
Neurotoxins Affecting Neuroexocytosis
2000 Standout
Anthrax protective antigen forms oligomers during intoxication of mammalian cells.
1994
A NEW STAPHYLOCOCCAL ENTEROTOXIN, ENTEROTOXIN F, ASSOCIATED WITH TOXIC-SHOCK-SYNDROME STAPHYLOCOCCUS AUREUS ISOLATES
1981
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Synaptic Vesicle Movements Monitored by Fluorescence Recovery after Photobleaching in Nerve Terminals Stained with FM1-43
1996
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of John L. Middlebrook being referenced
Cellular regulation of diphtheria toxin cell surface receptors
1989
Mosquito inoculation: An alternative bioassay for toxins
1988
Protection Strategies Against Botulinum Toxin
1995
Mapping of the antibody-binding regions on botulinum neurotoxin H-chain domain 855–1296 with antitoxin antibodies from three host species
1996
Identification of the site at which phospholipase A2 neurotoxins localize to produce their neuromuscular blocking effects
1993
Immunodiagnosis and Immunotherapy of Tetanus and Botulinum Neurotoxins
1995
Bacterial toxins: cellular mechanisms of action
1984
Ion-conducting channels produced by botulinum toxin in planar lipid membranes
1986
Specific antibodies against the Zn(2+)-binding domain of clostridial neurotoxins restore exocytosis in chromaffin cells treated with tetanus or botulinum A neurotoxin.
1994
Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: differential cytotoxicity
1977
Effects of beta-bungarotoxin and Naja naja atra snake venom phospholipase A2 on acetylcholine release and choline uptake in synaptosomes
1986
[12] Isolation and characterization of the Botulinum neurotoxins
1988
Inhibition of diphtheria toxin degradation and cytotoxic action by chloroquine.
1980
Protection of mammalian cells from diphtheria toxin by exogenous nucleotides
1979
Bacterial toxins: cellular mechanisms of action.
1984
Physicochemical Properties of Glucocorticoid Receptors from Mouse Fibroblasts*
1977
Association of diphtheria toxin with Vero cells. Demonstration of a receptor.
1978
Subcellular distribution of glucocorticoid receptors in mouse fibroblasts
1975
Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells.
1979
Effect of single and double peptide bond scission by trypsin on the structure and activity of staphylococcal enterotoxin C.
1976