Citation Impact

Citing Papers

Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts
2009
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
2017 Standout
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
2019 StandoutNobel
Formation of propionate and butyrate by the human colonic microbiota
2016 Standout
Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability
2016 StandoutNobel
A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome
2017 Standout
Antibiotics: past, present and future
2019 Standout
Role of the normal gut microbiota
2015 Standout
Photothermal Nanozyme‐Based Microneedle Patch against Refractory Bacterial Biofilm Infection via Iron‐Actuated Janus Ion Therapy
2022
Strategies for improving biological hydrogen production
2012
Trends and challenges in the microbial production of lignocellulosic bioalcohol fuels
2010
Novel approaches to treatingClostridium difficile-associated colitis
2015
The Role of Short-Chain Fatty Acids in Health and Disease
2014 Standout
Clostridium difficile Has an Original Peptidoglycan Structure with a High Level of N-Acetylglucosamine Deacetylation and Mainly 3-3 Cross-links
2011
Microbial tryptophan catabolites in health and disease
2018 Standout
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Live virus-free or die: coupling of antivirus immunity and programmed suicide or dormancy in prokaryotes
2012
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
2014 StandoutNature
Thermophilic lignocellulose deconstruction
2013
A universal biomolecular integral feedback controller for robust perfect adaptation
2019 Nature
Concepts and Mechanisms: Crossing Host Barriers
2013
c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases
2011
Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
2016 Nature
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
The Microbiome and Inflammatory Bowel Disease: Is There a Therapeutic Role for Fecal Microbiota Transplantation?
2012
Clostridium difficile infection: new developments in epidemiology and pathogenesis
2009
Burden of Clostridium difficile Infection in the United States
2015 Standout
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
2013 Nature
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Gut microbiome and health: mechanistic insights
2022 Standout
Role of the gut microbiota in immunity and inflammatory disease
2013 Standout
Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
2010 Standout
The role of iron and reactive oxygen species in cell death
2013 Standout
Predictors of First Recurrence of Clostridium difficile Infection: Implications for Initial Management
2012
Antibiotics in the clinical pipeline in 2011
2011
Designing antimicrobial peptides: form follows function
2011 Standout
Pyroptosis: mechanisms and diseases
2021 Standout
Environmental factors influencing the development and spread of antibiotic resistance
2017 Standout
Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity
2014 StandoutNobel
Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications
2011
Bacterial spore structures and their protective role in biocide resistance
2012
Lactobacillus acidophilus modulates the virulence of Clostridium difficile
2014
Next generation biofuel engineering in prokaryotes
2013
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome
2014 Nature
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Consequences of bile salt biotransformations by intestinal bacteria
2016
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites
2017 Nature
Assessment of Anti-Quorum Sensing Activity for Some Ornamental and Medicinal Plants Native to Egypt
2013
Influence of diet on the gut microbiome and implications for human health
2017 Standout
Waste biorefinery models towards sustainable circular bioeconomy: Critical review and future perspectives
2016 Standout
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
2018 Standout
Gut Microbiota-Produced Succinate Promotes C. difficile Infection after Antibiotic Treatment or Motility Disturbance
2014
Fermentative butanol production by clostridia
2008
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027
2011
Neutralization of Clostridium difficile Toxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain
2011
Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: A review
2018 Standout
Toxin B is essential for virulence of Clostridium difficile
2009 Nature
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
The pros, cons, and many unknowns of probiotics
2019 Standout
Impacts of biodiversity on the emergence and transmission of infectious diseases
2010 StandoutNature
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Glycoproteomics
2022 StandoutNobel
Gut Microbiota in Health and Disease
2010 Standout
Hydrogen production, storage, transportation and key challenges with applications: A review
2018 Standout
Protective Role of Commensals against Clostridium difficile Infection via an IL-1β–Mediated Positive-Feedback Loop
2012
Metabolic Engineering: Past and Future
2013
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex
2013
Critical Role for MyD88-Mediated Neutrophil Recruitment during Clostridium difficile Colitis
2012
Soil enzymes in a changing environment: Current knowledge and future directions
2012 Standout
Clostridium difficile Drug Pipeline: Challenges in Discovery and Development of New Agents
2015
Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile
2018
Review and evaluation of hydrogen production methods for better sustainability
2015 Standout
Effect of Essential Oils on Pathogenic Bacteria
2013 Standout
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Lignocellulosic biomass: a sustainable platform for the production of bio-based chemicals and polymers
2015 Standout
Introduction to the human gut microbiota
2017 Standout
Cellulosomes: Highly Efficient Nanomachines Designed to Deconstruct Plant Cell Wall Complex Carbohydrates
2010
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
2013 Standout
The Changing Epidemiology of Clostridium difficile Infections
2010
Stoichiometric and energetic analyses of non-photosynthetic CO2-fixation pathways to support synthetic biology strategies for production of fuels and chemicals
2012
Protein glycosylation: Sweet or bitter for bacterial pathogens?
2019
Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation
2016
Photothermal Nanomaterials: A Powerful Light-to-Heat Converter
2023 Standout
Nanobodies: Natural Single-Domain Antibodies
2013 Standout
Diagnosis of Clostridium difficile Infection: an Ongoing Conundrum for Clinicians and for Clinical Laboratories
2013
Toll-Like Receptor 5 Stimulation Protects Mice from Acute Clostridium difficile Colitis
2011

Works of John Heap being referenced

Clostridium difficile spore germination: an update
2010
Mathematical Modelling of the Sporulation-Initiation Network in Bacillus Subtilis Revealing the Dual Role of the Putative Quorum-Sensing Signal Molecule PhrA
2010
ClosTron-Mediated Engineering of Clostridium
2011
ClosTron-Targeted Mutagenesis
2010
The ClosTron: Mutagenesis in Clostridium refined and streamlined
2009
A modular system for Clostridium shuttle plasmids
2009
The ClosTron: A universal gene knock-out system for the genus Clostridium
2007
The role of toxin A and toxin B in Clostridium difficile infection
2010 Nature
Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability
2017
The emergence of ‘hypervirulence’ in Clostridium difficile
2010
The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type
2010
Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the tcdC Genotype and Toxin Production
2012
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker
2012
Synthetic negative feedback circuits using engineered small RNAs
2018
SleC Is Essential for Germination of Clostridium difficile Spores in Nutrient-Rich Medium Supplemented with the Bile Salt Taurocholate
2009
Rankless by CCL
2026