Citation Impact

Citing Papers

Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
A polymer physics perspective on driving forces and mechanisms for protein aggregation
2007
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Conformational constraints for amyloid fibrillation: the importance of being unfolded
2004
Firefly luciferase mutants as sensors of proteome stress
2011
Eukaryotic Proteasomes Cannot Digest Polyglutamine Sequences and Release Them during Degradation of Polyglutamine-Containing Proteins
2004
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Synthetic Molecular Motors and Mechanical Machines
2006 Standout
Polyglutamine Expansion in Ataxin-3 Does Not Affect Protein Stability
2004
Ideas of Order for Amyloid Fibril Structure
2002
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Unfolding the role of protein misfolding in neurodegenerative diseases
2003
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
Techniques to study amyloid fibril formation in vitro
2004
Structure of the cross-β spine of amyloid-like fibrils
2005 StandoutNature
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
β-Edge Interactions in a Pentadecameric Human Antibody Vκ Domain
2006 StandoutNobel
Role of histidine interruption in mitigating the pathological effects of long polyglutamine stretches in SCA1: A molecular approach
2003
Protein aggregation and neurodegenerative disease
2004 Standout
Graphene oxide strongly inhibits amyloid beta fibrillation
2012
Amyloid Protofilaments from the Calcium-binding Protein Equine Lysozyme: Formation of Ring and Linear Structures Depends on pH and Metal Ion Concentration
2003
Direct Observation of Aβ Amyloid Fibril Growth and Inhibition
2004
A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor
2003
CH/π Attraction: The Origin of Enantioselectivity in Transfer Hydrogenation of Aromatic Carbonyl Compounds Catalyzed by Chiralη6-Arene-Ruthenium(II) Complexes
2001 StandoutNobel
Cascade Reactions in Total Synthesis
2006 Standout
Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells
2002
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The ubiquitin–proteasome pathway in Parkinson's disease and other neurodegenerative diseases
2004
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
2012 Standout
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
2001
Protein aggregation processes: In search of the mechanism
2007
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Selective Neuronal Degeneration in Huntington's Disease
2006
Asymmetric 1,3-Dipolar Cycloaddition Reactions
1998 Standout
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
The Validity of the "Diradical" Hypothesis: Direct Femtoscond Studies of the Transition-State Structures
1994 StandoutScienceNobel
Supramolecular Polymerization
2009 Standout
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
2010 Standout
Facile Radical Trifluoromethylation of Lithium Enolates
2005
Organic Photoredox Catalysis
2016 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Stereocontrolled Synthesis of a Nonracemic Vitamin B12 A−B-Semicorrin
1997 StandoutNobel
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Mutational analysis of the structural organization of polyglutamine aggregates
2002
Synthetic Aspects of the Di-π-methane Rearrangement
1996
A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila
2003
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
2006
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
Functional Anthology of Intrinsic Disorder. 2. Cellular Components, Domains, Technical Terms, Developmental Processes, and Coding Sequence Diversities Correlated with Long Disordered Regions
2007
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol
2019 Standout
3D structure of Alzheimer's amyloid-β(1–42) fibrils
2005 Standout
Intrinsic disorder in proteins associated with neurodegenerative diseases
2009
Die Erhaltung der Orbitalsymmetrie
1969 StandoutNobel
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Conceptual Density Functional Theory
2003 Standout
Orbital Symmetry Control of Chemical Reactions
1970 StandoutScienceNobel
The Conservation of Orbital Symmetry
1969 StandoutNobel
Emerging Principles of Conformation-Based Prion Inheritance
2003
Transition Metal-Mediated Cycloaddition Reactions
1996 Standout
Ground- and Excited-State Reactions of Norbornene and Isomers: A CASSCF Study and Comparison with Femtosecond Experiments
1999 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Organic Polyvalent Iodine Compounds
1996 Standout
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Formation of A Dihaloenone of Homoadamantanone
1995
Recognition of stereochemical paths by orbital interaction
1971 StandoutNobel
Expansion to Seven-Membered Rings
2000
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Radical Trifluoromethylation of Titanium Ate Enolate
2005
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
2016 Standout
Photochromism of Diarylethene Molecules and Crystals: Memories, Switches, and Actuators
2014 Standout
Nucleus-Independent Chemical Shifts (NICS) as an Aromaticity Criterion
2005 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Photochemical Reaction Containers as Energy and Electron-Transfer Agents
2013
Role of Frontier Orbitals in Chemical Reactions
1982 StandoutScienceNobel
The Vinylogous Aldol Reaction:  A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver
2000 Standout
Structural properties of Aβ protofibrils stabilized by a small molecule
2005
The Tail Wagging the Dog: Insights into Catalysis in R67 Dihydrofolate Reductase
2010
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience

Works of John Hamilton being referenced

Lysosomal acid lipase deficiency – An under-recognized cause of dyslipidaemia and liver dysfunction
2014
A Microtiter Plate Assay for Polyglutamine Aggregate Extension
2001
Amyloid-like Features of Polyglutamine Aggregates and Their Assembly Kinetics
2002
Acetolysis of 4-homoadamantyl tosylate
1969
Role of Ionic Interactions in Ligand Binding and Catalysis of R67 Dihydrofolate Reductase
2003
Photoisomerization of mono- and dibenzobarrelenes
1968
Rankless by CCL
2026