Standout Papers
Citation Impact
Citing Papers
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
The discovery and development of HMG-CoA reductase inhibitors.
1992
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
An Antibody Reactive with Domain 4 of the Platelet-derived Growth Factor β Receptor Allows BB Binding while Inhibiting Proliferation by Impairing Receptor Dimerization
1997
Endogenously elicited antibodies to platelet derived growth factor‐BB and platelet cytosolic protein inhibit aortic lesion development in the cholesterol‐fed rabbit
1997
Elevated Levels of PDGF α Receptors in Keloid Fibroblasts Contribute to an Enhanced Response to PDGF
1994
Creative blocks: cell-cycle checkpoints and feedback controls
1992 Nature
Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds.
1995
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Platelet-derived growth factor (PDGF): Actions and mechanisms in vascular smooth muscle
1996
In vivofootprinting and functional analysis of the human c-sis/PDGF B gene promoter provides evidence for two binding sites for transcriptional activators
1995
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Production of Platelet-Derived Growth Factor–like Mitogen by Smooth-Muscle Cells from Human Atheroma
1988
Platelet-derived Growth Factor (PDGF)-induced Ca2+ Signaling in the CG4 Oligodendroglial Cell Line and in Transformed Oligodendrocytes Expressing the β-PDGF Receptor
1997
Role of platelet‐derived growth factor in wound healing
1991
Distribution and Functions of Platelet-Derived Growth Factors and Their Receptors during Embryogenesis
1997
Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets
1990
Signals controlling the expression of PDGF
1996
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein
1988 StandoutNatureNobel
Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo.
1993
Variant in Promoter Region of Platelet-Derived Growth Factor Receptor-α (PDGFRα) Gene Is Associated with the Severity and Allergic Status of Childhood Asthma
2006
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
1988 StandoutNature
Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product
1992 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
PDGF and cardiovascular disease
2004
G protein—coupled receptor kinases
1993 StandoutNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
PLATELET-DERIVED GROWTH FACTOR
1989
Expression of growth factors in early wound healing in rat skin
1994
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
Rapid Activation of PDGF-A and -B Expression at Sites of Lung Injury in Asbestos-exposed Rats
1997
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Platelet adhesion and myointimal proliferation in canine pulmonary arteries.
1981
Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor
1983 Science
Complete covalent structure of human .beta.-thromboglobulin
1978
Detection of a Possible Intermediate in Oxidative Phosphorylation
1961 StandoutNatureNobel
Crystal structure of human platelet-derived growth factor BB.
1992
Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis.
1989
Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor
1984
Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF
1988 Science
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor.
1985 StandoutNobel
Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia.
1981
The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.
1985
Human Platelet-Derived Growth Factor (PDGF): Amino-Terminal Amino Acid Sequence
1983 Science
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
A macrophage-dependent factor that stimulates the proliferation of fibroblasts in vitro.
1976
Developmentally regulated production of platelet-derived growth factor-like molecules
1984 Nature
PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASE
1975 Standout
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Enzymatic Breakage and Joining of Deoxyribonucleic Acid
1971
Platelet-derived growth factor in vivo: levels, activity, and rate of clearance
1984
Specific covalent binding of platelet-derived growth factor to human plasma alpha 2-macroglobulin.
1984
Transfers and exchanges of esterified cholesterol between plasma lipoproteins
1982
Role of platelet-derived growth factor in vascular remodeling during pulmonary hypertension in the ovine fetus
2003
Senescence and Vascular Disease
1975
Platelet-derived growth factor. II. Specific binding to cultured cells.
1982
Connective tissue activation
1979
Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.
1981
Enzymatic Synthesis of Deoxyribonucleotides
1963
Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes.
1983
Control of proliferation of bovine vascular endothelial cells
1977
Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets
1986 StandoutScience
Human megakaryocyte stimulation of proliferation of bone marrow fibroblasts
1981
Human-Proto-Oncogene Nucleotide Sequences Corresponding to the Transforming Region of Simian Sarcoma Virus
1984 Science
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Anti–Monocyte Chemoattractant Protein-1/Monocyte Chemotactic and Activating Factor Antibody Inhibits Neointimal Hyperplasia in Injured Rat Carotid Arteries
1999
Recent advances in molecular pathology
1984
Platelet-derived growth factor concentrations in platelet-poor plasma and urine from patients with myeloproliferative disorders
1989
Exaggerated Spontaneous Release of Platelet-Derived Growth Factor by Alveolar Macrophages from Patients with Idiopathic Pulmonary Fibrosis
1987
Bacteriophage Genes and Bacterial Functions
1962 StandoutScienceNobel
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Platelet-derived growth factor promotes proliferation of erythropoietic progenitor cells in vitro.
1983
Cultured endothelial cells produce a platelet-derived growth factor-like protein
1983
Studies of the release from human platelets of the growth factor for cultured human arterial smooth muscle cells.
1978
Role of p38 Mitogen-Activated Protein Kinase in Neointimal Hyperplasia After Vascular Injury
2000
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.
1994
Lipoproteins and atherosclerosis. A look back and a look ahead.
1983
Anti-peptide antibodies detect oncogene-related proteins in urine.
1985
Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.
1986
Dual control of cell growth by somatomedins and platelet-derived growth factor.
1979
Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells
1982
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Total Synthesis of α-Pyrone Meroterpenoids, Novel Bioactive Microbial Metabolites
2005 StandoutNobel
Differential expression and localization of insulin-like growth factors I and II in cutaneous wounds of diabetic and nondiabetic mice.
1997
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture
1988
Correct integration of retroviral DNA in vitro
1987 StandoutNobel
Regulation of Plasma Cholesterol by Lipoprotein Receptors
1981 StandoutScienceNobel
Ultrastructural studies on the localization of IgG in the aortic endothelium and subendothelial intima of atherosclerotic and nonatherosclerotic rabbits
1980
Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts
1983 StandoutNatureNobel
Developmental Expression of Platelet-Derived Growth Factor α-Receptor in Neurons and Glial Cells of the Mouse CNS
1997
Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor.
1982
An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis
1978
Simian Sarcoma Virus—Transformed Cells Secrete a Mitogen Identical to Platelet-Derived Growth Factor
1984 Science
Production of platelet-derived growth factorlike protein by rat mesangial cells in culture.
1987
Collagen-induced binding to human platelets of platelet-derived growth factor leading to inhibition of P43 and P20 phosphorylation
1989
In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins.
1988
Phenotype-dependent response of cultured aortic smooth muscle to serum mitogens.
1981
Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells
1983 Science
Platelet-derived growth factor stimulates low density lipoprotein receptor activity in cultured human fibroblasts.
1980
Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty.
1992
Cellular transformation by coordinated action of three peptide growth factors from human platelets
1984 Nature
Stimulation of DNA Synthesis in Quiescent Cultured Cells: Exogenous Agents, Internal Signals, and Early Events
1980
Synthesis of Connective Tissue Macromolecules by Smooth Muscle
1979
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Radioimmunoassay of a human serum growth factor for Balb/c-3T3 cells: derivation from platelets.
1977
Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.
1982
Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process
1977
Increased platelet-derived growth factor A-chain expression in human uterine smooth muscle cells during the physiologic hypertrophy of pregnancy.
1990
Regulation of production of a platelet‐derived growth factor‐like protein by cultured bovine aortic endothelial cells
1984
Regulation of differentiated properties and proliferation of arterial smooth muscle cells.
1990
Magnesium and lipids in cardiovascular disease.
1986
An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues
1974 StandoutNobel
Hormonal Requirements for Growth of Arterial Smooth Muscle Cells in vitro: An Endocrine Approach to Atherosclerosis
1981 Science
Platelet-derived growth factor: purification and partial characterization.
1979
Characterization of the receptor for platelet-derived growth factor on human fibroblasts. Demonstration of an intimate relationship with a 185,000-Dalton substrate for the platelet-derived growth factor-stimulated kinase.
1983
The Growth Factor—Platelet—Transformation Connection
1986
Roles of PDGF in animal development
2003
Platelet-derived growth factor enhances in vitro erythropoiesis via stimulation of mesenchymal cells.
1985
Growth factors adherent to cell substrate are mitogenically active in situ
1982 Nature
Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin. Possible role of a platelet endoglycosidase.
1982
Enzymatic modification of proteins with a geranylgeranyl isoprenoid.
1991
Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.
1986
Atherogenic Hyperlipoproteinemia: The Cellular and Molecular Biology of Plasma Lipoproteins Altered by Dietary Fat and Cholesterol
1982
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
1983 Nature
Purification and initial characterization of a type beta transforming growth factor from human placenta.
1983
Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells.
1993
Human platelet-derived growth factor. Purification and resolution into two active protein fractions.
1981
Stimulation of aortic smooth muscle cell mitogenesis by serotonin.
1986
Platelet-derived growth factor. Specific binding to target cells.
1982
Detection of c- sis Transcripts and Synthesis of PDGF-Like Proteins by Human Osteosarcoma Cells
1984 Science
Cholesterol Turnover in Man
1970
Homocystinemia
1974
Growth factors in porcine full and partial thickness burn repair. Differing targets and effects of keratinocyte growth factor, platelet-derived growth factor-BB, epidermal growth factor, and neu differentiation factor.
1995
Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.
1983 Standout
Stimulated Activation of Platelet-Derived Growth Factor Receptor In Vivo in Balloon-Injured Arteries
1997
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Expression and Function of a Recombinant PDGF B Gene in Porcine Arteries
1995
Platelet-derived growth factor promotes polymorphonuclear leukocyte activation
1984
The effect of systemically administered PDGF-BB on the rodent skeleton
1996
The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.
1977
Platelet-derived growth factor. I. High yield purification and evidence for multiple forms.
1982
Platelet-derived growth factor. Isolation by a large-scale procedure and analysis of subunit composition
1981
Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.
1982
Purification of human platelet-derived growth factor.
1979
Respiratory Control and Compartmentation of Substrate Level Phosphorylation in Liver Mitochondria
1961
The platelet-derived growth factor
1978
Platelet-derived growth factor BB induces functional vascular anastomoses in vivo.
1995
Human platelet-derived growth factor stimulates amino acid transport and protein synthesis by human diploid fibroblasts in plasma-free media.
1982
Proteoglycans in primate arteries. II. Synthesis and secretion of glycosaminoglycans by arterial smooth muscle cells in culture.
1975
Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets.
1983
George Lyman Duff Memorial Lecture. Atherosclerosis: a problem of the biology of arterial wall cells and their interactions with blood components.
1981
Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor
1983 Nature
Human platelet-derived growth factor (PDGF): purification of PDGF-I and PDGF-II and separation of their reduced subunits.
1981
Human arterial wall cells secrete factors that are chemotactic for monocytes.
1983
The Biology of Cancer Invasion and Metastasis
1978
The Pathogenesis of Atherosclerosis: Atherogenesis and Inflammation
1989
A significant part of macrophage-derived growth factor consists of at least two forms of PDGF
1985
Nucleotides Derived from Enzymatic Digests of Nucleic Acids of T2, T4, and T6 Bacteriophages
1960
Serum stimulation of phospholipase A2 and prostaglandin release in 3T3 cells is associated with platelet-derived growth-promoting activity.
1980
The pathogenesis of atherosclerosis
1979
PDGF signalling is required for gastrulation of Xenopus laevis
1995
Resistance to Arteriosclerosis in Pigs with von Willebrand's Disease
1978
Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate.
1976
Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
1992 StandoutScienceNobel
Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.
1991 Standout
Phylogenetic analysis of platelet-derived growth factor by radio-receptor assay.
1982
The Pathogenesis of Atherosclerosis
1976 Standout
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region
1981 StandoutNobel
Independent Pathways for Secretion of Cholesterol and Apolipoprotein E by Macrophages
1983 StandoutScienceNobel
Platelet factor 4 is chemotactic for neutrophils and monocytes.
1981
Platelet-derived growth factor stimulates activity of low density lipoprotein receptors.
1980
Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells.
1975
Plasma binding proteins for platelet-derived growth factor that inhibit its binding to cell-surface receptors.
1984
Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth
1981
Platelet‐derived growth factor AA homodimer is the predominant isoform in human platelets and acute human wound fluid
1992
Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.
1994 Standout
Platelet‐derived growth factor stimulates the phosphorylation of ribosomal protein S6
1983
Hyperlipidemia and Atherosclerosis
1976 Science
[32] Reconstitution of high-density lipoproteins
1986
Evidence That the v- sis Gene Product Transforms by Interaction with the Receptor for Platelet-Derived Growth Factor
1985 Science
Transient up-regulation of P2Y2nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
1997 StandoutNobel
The biology of platelet-derived growth factor
1986 Standout
Physiological Ce:Roles of Lecithin—Cholesterol Acyltransferase
1970
Identification of a PDGF‐like mitoattractant produced by NIH/3T3 cells after transformation with SV40
1985
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components.
1978
Control of growth of mammalian cells in cell culture
1975 Nature
Molecular cloning of gene sequences regulated by platelet-derived growth factor
1983
Isoprenylation of a protein kinase. Requirement of farnesylation/alpha-carboxyl methylation for full enzymatic activity of rhodopsin kinase.
1992 StandoutNobel
The Platelet-Derived Growth Factor Receptor
1985
Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard.
1994 StandoutNobel
The Pathogenesis of Atherosclerosis — An Update
1986 Standout
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Isolation and characterization of a human serum cholesteryl ester transfer protein.
1978
The B chain of PDGF alone is sufficient for mitogenesis.
1985
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules.
1980
A CHEMICAL BASIS FOR THE HOST-INDUCED MODIFICATION OF T-EVEN BACTERIOPHAGES
1963 StandoutNobel
Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.
1988 StandoutNobel
Human platelet-derived growth factor: radioimmunoassay and discovery of a specific plasma-binding protein.
1983
Vessel injury, platelet adherence, and platelet survival.
1983
Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.
1976
Works of John Glomset being referenced
Response to injury and atherogenesis.
1977
Role of platelet factors in the growth of cells in culture.
1978
Studies of Primate Arterial Smooth Muscle Cells in Relation to Atherosclerosis
1974
Methods for Studying Nucleotide Metabolism in Synchronized Cultures of Protozoa.
1955
Structural characterization of prenyl groups attached to proteins
1990
The production of 32P-labeled mitochondrial nucleotides
1955
ROLE OF THE PLATELET IN ATHEROGENESIS*
1976
A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro
1974 Standout
In vitro incorporation of cholesterol-14C in to very low density lipoprotein cholesteryl esters
1968
The prenylation of proteins
1991
Plasma Lipoproteins in Familial Lecithin:Cholesterol Acyltransferase Deficiency: Effects of Incubation with Lecithin: Cholesterol Acyltransferase in vitro
1975