Citation Impact
Citing Papers
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Opposing Roles of CD28:B7 and CTLA-4:B7 Pathways in Regulating In Vivo Alloresponses in Murine Recipients of MHC Disparate T Cells
1999
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
Functional diversity of helper T lymphocytes
1996 StandoutNature
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Necroptosis and its role in inflammation
2015 StandoutNature
Enzyme-Catalyzed Activation of Anticancer Prodrugs
2004
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Prodrug Strategies in Anticancer Chemotherapy
2007
Innate Immunity: The Virtues of a Nonclonal System of Recognition
1997 Standout
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
2012
Selective activation of anticancer prodrugs by monoclonal antibody–enzyme conjugates
2001
The IKK NF-κB system: a treasure trove for drug development
2004
Chemical probing reveals insights into the signaling mechanism of inflammasome activation
2010
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Interleukin-6 expression and regulation in astrocytes
1999
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Treatment of Murine Lupus with CTLA4Ig
1994 Science
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Tumor-activated Prodrugs—A New Approach to Cancer Therapy
2004
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
1994
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Cancer-related inflammation
2008 StandoutNature
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Involvement of CD40 Ligand-CD40 and CTLA4-B7 Pathways in Murine Acute Graft-Versus-Host Disease Induced by Allogeneic T Cells Lacking CD28
1998
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
NF-κB Regulates PD-1 Expression in Macrophages
2015
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4+ T Cells
1998 StandoutNobel
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
2003 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
CD28/B7 SYSTEM OF T CELL COSTIMULATION
1996 Standout
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Molecular Basis of T Cell Inactivation by CTLA-4
1998 Science
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses
2001 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition
2014
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction
2003 StandoutNobel
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105
2004
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Inflammatory Bowel Disease
2010 Standout
Drug Delivery Systems: Entering the Mainstream
2004 StandoutScience
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Dendritic Cells Pulsed with Intact Streptococcus pneumoniae Elicit both Protein- and Polysaccharide-specific Immunoglobulin Isotype Responses In Vivo through Distinct Mechanisms
2001
Synthesis of an organoinsulin molecule that can be activated by antibody catalysis
2001 StandoutNobel
Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease
2004
Enzyme-Responsive Snap-Top Covered Silica Nanocontainers
2008 StandoutNobel
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
Opposing functions of IKKβ during acute and chronic intestinal inflammation
2008
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells
2000 StandoutNobel
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
2005 Standout
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Antibody-directed enzyme prodrug therapy (ADEPT): a review
1997
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Works of John F. MacMaster being referenced
An inhibitor of I?B kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice
2003
CTLA4Ig TREATMENT AMELIORATES THE LETHALITY OF MURINE GRAFT-VERSUS-HOST DISEASE ACROSS MAJOR HISTOCOMPATIBILITY COMPLEX BARRIERS
1994
BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice
2003
Regulation of Inflammatory Responses by Oncostatin M
1999
Intratumoral generation of 5-fluorouracil mediated by an antibody-cytosine deaminase conjugate in combination with 5-fluorocytosine.
1994
In vitro and in vivo activities of a doxorubicin prodrug in combination with monoclonal antibody beta-lactamase conjugates.
1995