Standout Papers
- Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance (2004)
- Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance (2004)
- Induction of the TRPM-2 gene in cells undergoing programmed death. (1989)
Citation Impact
Citing Papers
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.
1991
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview
1992
Expression of GHF-1 protein in mouse pituitaries correlates both temporally and spatially with the onset of growth hormone gene activity
1990
Posterior pattern formation in C. elegans involves position-specific expression of a gene containing a homeobox
1988 StandoutNobel
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
1990 Nature
Transduction of bitter and sweet taste by gustducin
1996 Nature
Brown and beige fat: development, function and therapeutic potential
2013 Standout
A family of candidate taste receptors in human and mouse
2000 StandoutNatureNobel
Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*
1989 Standout
Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure
2009
Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain
1989 Nature
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Disruption of imprinting caused by deletion of the H19 gene region in mice
1995 Nature
The delta opioid receptor: an evolving target for the treatment of brain disorders
2011
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
2014
Molecular Characterization of the Dendritic Growth Cone: Regulated mRNA Transport and Local Protein Synthesis
1996
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Retinopathy of prematurity
2013 Standout
Monooxygenase X, a Member of the Copper-dependent Monooxygenase Family Localized to the Endoplasmic Reticulum
2004
Physical linkage of two mammalian imprinted genes, H19 and insulin–like growth factor 2
1992
Genes Expressed in Neurons of Adult Male Drosophila
1997 StandoutNobel
Apoptosis (the 1992 Frank Rose Memorial Lecture)
1993
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
Identification and Characterization of Three New Alternatively Spliced μ-Opioid Receptor Isoforms
1999
Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation
2011
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
Regulation of Opioid Receptor Trafficking and Morphine Tolerance by Receptor Oligomerization
2002
New insights into copper monooxygenases and peptide amidation: structure, mechanism and function
2000
Nigrostriatal Dopaminergic Deficits and Hypokinesia Caused by Inactivation of the Familial Parkinsonism-Linked Gene DJ-1
2005
Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks
2001 Standout
CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP
1995 StandoutNobel
G Protein-Coupled Receptor Heteromerization: A Role in Allosteric Modulation of Ligand Binding
2011
Caenorhabditis elegans has scores of homoeobox-containing genes
1989 StandoutNatureNobel
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Parental imprinting of the mouse insulin-like growth factor II gene
1991
Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey
1988
Gustducin is a taste-cell-specific G protein closely related to the transducins
1992 Nature
The unc-86 gene product couples cell lineage and cell identity in C. elegans
1990 StandoutNobel
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
A Chemosensory Gene Family Encoding Candidate Gustatory and Olfactory Receptors in Drosophila
2001 StandoutNobel
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6
1992 StandoutNatureNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
Adaptive thermogenesis in adipocytes: Is beige the new brown?
2013
Programmed Cell Death in the Immune System
1991
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Understanding Retinopathy of Prematurity: Update on Pathogenesis
2011
Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain
2009
A "Neural" Enzyme in Nonbilaterian Animals and Algae: Preneural Origins for Peptidylglycine -Amidating Monooxygenase
2012
Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis
2009 Standout
Structure of the δ-opioid receptor bound to naltrindole
2012 StandoutNatureNobel
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Segmental patterns of neuronal development in the chick hindbrain
1989 Nature
Recent advances in selective opioid receptor agonists and antagonists
2003
Parental imprinting of anIGF‐2transgene
1993
Regulation of transcription and cell identity by POU domain proteins
1991 StandoutNobel
Allelic inactivation regulates olfactory receptor gene expression
1994 StandoutNobel
Retinopathy of prematurity
2007
Peptidylgycine α‐amidating monooxygenase and copper: A gene–nutrient interaction critical to nervous system function
2010
Morphine-like Opiates Selectively Antagonize Receptor-Arrestin Interactions
2010
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.
1990
A Pharmacokinetic and Dosing Study of Intravenous Insulin-Like Growth Factor-I and IGF-Binding Protein-3 Complex to Preterm Infants
2009
Mediators involved in retinopathy of prematurity and emerging therapeutic targets
2011
Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos
1988
Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors I and II
1992
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
PHM Is Required for Normal Developmental Transitions and for Biosynthesis of Secretory Peptides in Drosophila
2000
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus
1991
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Copper Active Sites in Biology
2014 Standout
Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos.
1992
A look at the Caenorhabditis elegans Kex2/Subtilisin-like proprotein convertase family
2000
Physiological Roles of G Protein–Coupled Receptor Kinases and Arrestins
2007
Hox patterning of the vertebrate rib cage
2007 StandoutNobel
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
2006 StandoutNobel
Role of insulin-like growth factors in embryonic and postnatal growth
1993 Standout
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Postnatal Decrease in Circulating Insulin-Like Growth Factor-I and Low Brain Volumes in Very Preterm Infants
2011
Bimodal and graded expression of theXenopushomeobox geneXhox3during embryonic development
1989
p53-mediated cell death: relationship to cell cycle control.
1993
CAPS-1 and CAPS-2 Are Essential Synaptic Vesicle Priming Proteins
2007
Expression of homeo box genes during mouse development: a review.
1988
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Do multigene families regulate vertebrate development?
1988
The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo
1991 StandoutNobel
Identification of mRNAs Associated with Programmed Cell Death in Immature Thymocytes
1991
Making Structural Sense of Dimerization Interfaces of Delta Opioid Receptor Homodimers
2011
Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.
1985
Synapsins: Mosaics of Shared and Individual Domains in a Family of Synaptic Vesicle Phosphoproteins
1989 StandoutScienceNobel
Nematode homeobox cluster
1991 StandoutNatureNobel
Differential Response to Morphine of the Oligomeric State of μ-Opioid in the Presence of δ-Opioid Receptors
2011
Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.
1985
Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity.
1988
Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.
1993 StandoutNobel
Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene.
1992
Works of John E. Pintar being referenced
Tissue-Specific and Developmentally Regulated Transcription of the Insulin-Like Growth Factor 2 Gene
1987
Epidermal stem cells are retained in vivo throughout skin aging
2008
The Expression Pattern of an Insulin-Like Growth Factor (IGF)-Binding Protein Gene Is Distinct from IGF-II in the Midgestational Rat Embryo
1990
Retention of heroin and morphine–6β–glucuronide analgesia in a new line of mice lacking exon 1 of MOR–1
1999
Embryonic and Uterine Expression Patterns of Peptidylglycine α-Amidating Monooxygenase Transcripts Suggest a Widespread Role for Amidated Peptides in Development
1997
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
The role of prohormone convertase‐2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study
2006
The Developmental Expression in the Rat CNS and Peripheral Tissues of Proteases PC5 and PACE4 mRNAs: Comparison with Other Proprotein Processing Enzymes
1997
Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse
2005
Analysis of Proopiomelanocortin Gene Expression during Prenatal Development of the Rat Pituitary Gland
1989
Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices
2008
Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice
1999
μ‐opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR‐1
1999
Targeted Deletion of the Vgf Gene Indicates that the Encoded Secretory Peptide Precursor Plays a Novel Role in the Regulation of Energy Balance
1999
Transiently catecholaminergic (TC) cells in the bowel of the fetal rat: Precursors of noncatecholaminergic enteric neurons
1990
Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors
1999
Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs
1992
Comparison of Receptor Mechanisms and Efficacy Requirements for δ-Agonist-Induced Convulsive Activity and Antinociception in Mice
2002
Expression of the gene for the neuronal intermediate filament protein α‐internexin coincides with the onset of neuronal differentiation in the developing rat nervous system
1994
Essential role of mu opioid receptor in the regulation of delta opioid receptor–mediated antihyperalgesia
2007
Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance
2004 StandoutNobel
Targeted mutagenesis of processing enzymes and regulators: Implications for development and physiology
2003
Region-specific expression of mouse homeobox genes in the embryonic mesoderm and central nervous system.
1987
Reversal of Physiological Deficits Caused by Diminished Levels of Peptidylglycine α-Amidating Monooxygenase by Dietary Copper
2008
Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice
2002
Induction of the TRPM-2 Gene in Cells Undergoing Programmed Death
1989
A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia
2004
Developmental expression of VGF mRNA in the prenatal and postnatal rat
1998
Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice.
2002
Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis
1990
Mice lacking δ‐opioid receptors resist the development of diet‐induced obesity
2012
Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development.
1994
Specificity of antisera prepared against pure bovine MAO-B
1983
Female preproenkephalin-knockout mice display altered emotional responses
2001
The embryonic pattern of rat insulin-like growth factor-I gene expression suggests a role in induction and early growth of the liver.
1992
Pattern of the insulin-like growth factor II gene expression during rat embryogenesis
1988
IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth
2007
Induction of the TRPM-2 gene in cells undergoing programmed death.
1989 Standout