Citation Impact
Citing Papers
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
CD4 + Regulatory T Cells Control T H 17 Responses in a Stat3-Dependent Manner
2009 Science
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Bacterial Persistence as a Phenotypic Switch
2004 StandoutScience
Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection
2011
IL-23 plays a key role in Helicobacter hepaticus –induced T cell–dependent colitis
2006
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Delayed protection by ESAT-6–specific effector CD4+ T cells after airborne M. tuberculosis infection
2008
Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis
2009
Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis –Infected Macrophages
2014
TPL-2–ERK1/2 Signaling Promotes Host Resistance against Intracellular Bacterial Infection by Negative Regulation of Type I IFN Production
2013
Hypervirulent M. tuberculosis W/Beijing Strains Upregulate Type I IFNs and Increase Expression of Negative Regulators of the Jak-Stat Pathway
2005
Interleukin-10 Promotes Mycobacterium tuberculosis Disease Progression in CBA/J Mice
2008
IL-12-Impaired and IL-12-Secreting Dendritic Cells Produce IL-23 upon CD154 Restimulation
2008
Interleukin-23 Restores Immunity to Mycobacterium tuberculosis Infection in IL-12p40-Deficient Mice and Is Not Required for the Development of IL-17-Secreting T Cell Responses
2006
Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis
2007
The Type I IFN Response to Infection with Mycobacterium tuberculosis Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis
2007
IL-23 Receptor Regulates Unconventional IL-17–Producing T Cells That Control Bacterial Infections
2010
Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs
2008
Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria
2007
IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guerin Infection
2007
TLR4 Mediates Vaccine-Induced Protective Cellular Immunity to Bordetella pertussis : Role of IL-17-Producing T Cells
2006
IL-23 Is Required for Protection against Systemic Infection with Listeria monocytogenes
2009
Dectin-1 Interaction with Mycobacterium tuberculosis Leads to Enhanced IL-12p40 Production by Splenic Dendritic Cells
2007
Major Role of γδ T Cells in the Generation of IL-17+ Uveitogenic T Cells
2009
Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis
2010
Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response
2011
Innate IL-17-producing cells: the sentinels of the immune system
2010 Standout
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance
2007
Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?
2007
Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
2006
Immunological biomarkers of tuberculosis
2011
Neutrophils and intracellular pathogens: beyond phagocytosis and killing
2006
IL-23 mediates inflammatory responses to mucoidPseudomonas aeruginosalung infection in mice
2006
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
The roles of IL‐17A in inflammatory immune responses and host defense against pathogens
2008
Tuberculosis: a problem with persistence
2003
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
TH17 cells in development: an updated view of their molecular identity and genetic programming
2008
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Mycolic Acid Modification by the mmaA4 Gene of M. tuberculosis Modulates IL-12 Production
2008
Initiation and regulation of T-cell responses in tuberculosis
2011
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells
2006
The role of IL-10 in immune regulation during M. tuberculosis infection
2011
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
2008
Revisiting the role of the granuloma in tuberculosis
2012
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
2008
Interleukin‐17 in host defence against bacterial, mycobacterial and fungal pathogens
2008
Type I interferons in infectious disease
2015 Standout
CD4 is required for the development of a protective granulomatous response to pulmonary tuberculosis
2002
Interleukin-12 and tuberculosis: an old story revisited
2007
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
Pattern Recognition Receptors and Inflammation
2010 Standout
Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity
2011
IFN-γ and NO in mycobacterial disease: new jobs for old hands
2002
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo
2008
Induction and effector functions of TH17 cells
2008 Nature
Role of interleukin-12 family cytokines in the cellular response to mycobacterial disease
2009
Tuberculosis vaccine development: strength lies in tenacity
2012
Early T‐cell responses in tuberculosis immunity
2008
Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis
2007
Half-truths and selective memory: Interferon gamma, CD4+ T cells and protective memory against tuberculosis
2007
IL-23 and Th17 cytokines in intestinal homeostasis
2008
Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques
2009 StandoutNobel
Enhanced protection to Mycobacterium tuberculosis infection in IL‐10‐deficient mice is accompanied by early and enhanced Th1 responses in the lung
2010
IL-23 and IL-17 in tuberculosis
2008
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine
2008 Standout
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
2009
A Gamma Interferon Independent Mechanism of CD4 T Cell Mediated Control of M. tuberculosis Infection in vivo
2011
Immunity, Inflammation, and Cancer
2010 Standout
IL-23 promotes tumour incidence and growth
2006 Nature
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-γ-induced cell death
2008
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
2010 Nature
Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
2007 Standout
Signalling through C-type lectin receptors: shaping immune responses
2009
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice
2010
The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
2008 Standout
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Cancer immunotherapy comes of age
2011 StandoutNature
IL‐23‐dependent IL‐17 drives Th1‐cell responses following Mycobacterium bovis BCG vaccination
2011
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Interleukin 17-Producing γδ T Cells Increased in Patients with Active Pulmonary Tuberculosis
2008
Th17 Cell Differentiation: The Long and Winding Road
2008
Decreased IFN- γ and increased IL-4 production by human CD8+ T cells in response toMycobacterium tuberculosis in tuberculosis patients
2002
Th17: the third member of the effector T cell trilogy
2007
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Hypercytokinaemia accompanies HIV–tuberculosis immune reconstitution inflammatory syndrome
2010
Points of control in inflammation
2002 StandoutNature
Th17 cells and mucosal host defense
2007
C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
2009
Cancer-related inflammation
2008 StandoutNature
Confronting the scientific obstacles to global control of tuberculosis
2008
Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns
2010
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Understanding the IL-23–IL-17 immune pathway
2005
Comprehensive Integration of Single-Cell Data
2019 Standout
Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3‐signaling chemokines
2003
Role of innate cytokines in mycobacterial infection
2011
Mycobacterium tuberculosis Inhibits Neutrophil Apoptosis, Leading to Delayed Activation of Naive CD4 T cells
2012
Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by Bacteria Promotes Regulatory Properties of Neutrophils
2009
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Analysis of Nitric Oxide Synthase and Nitrotyrosine Expression in Human Pulmonary Tuberculosis
2002
Interferon-γ: an overview of signals, mechanisms and functions
2003 Standout
Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis
2010
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
The adaptor molecule CARD9 is essential for tuberculosis control
2010
Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response
2008
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Effects on Coagulation and Fibrinolysis Induced by Influenza in Mice With a Reduced Capacity to Generate Activated Protein C and a Deficiency in Plasminogen Activator Inhibitor Type 1
2006
IL-17 Production Is Dominated by γδ T Cells rather than CD4 T Cells during Mycobacterium tuberculosis Infection
2006
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells
2007
Tuberculosis Pathogenesis and Immunity
2011
Th17 T cells: Linking innate and adaptive immunity
2007
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes
2008
IFN-αβ and Self-MHC Divert CD8 T Cells into a Distinct Differentiation Pathway Characterized by Rapid Acquisition of Effector Functions
2010
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
NK Cell-Derived IFN-γ Differentially Regulates Innate Resistance and Neutrophil Response in T Cell-Deficient Hosts Infected with Mycobacterium tuberculosis
2006
Nitric oxide and the immune response
2001 Standout
Visualization of mycobacterial membrane dynamics in live cells
2017 StandoutNobel
Inhibition of Major Histocompatibility Complex II Expression and Antigen Processing in Murine Alveolar Macrophages byMycobacterium bovisBCG and the 19-Kilodalton Mycobacterial Lipoprotein
2004
IL-17 and Th17 Cells
2009 Standout
Interleukin-23 (IL-23)-IL-17 Cytokine Axis in Murine Pneumocystis carinii Infection
2007
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Mice Lacking Bioactive IL-12 Can Generate Protective, Antigen-Specific Cellular Responses to Mycobacterial Infection Only if the IL-12 p40 Subunit Is Present
2002
Cutting Edge: Toll-Like Receptor (TLR)2- and TLR4-Mediated Pathogen Recognition in Resistance to Airborne Infection with Mycobacterium tuberculosis
2002
Lung Neutrophils Facilitate Activation of Naive Antigen-Specific CD4+ T Cells during Mycobacterium tuberculosis Infection
2011
Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung
2010
Blockade of IL-10 Signaling during Bacillus Calmette-Guérin Vaccination Enhances and Sustains Th1, Th17, and Innate Lymphoid IFN-γ and IL-17 Responses and Increases Protection to Mycobacterium tuberculosis Infection
2012
Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis
2010
Type I interferon: friend or foe?
2010
The Immune Response in Tuberculosis
2013 Standout
IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway
2009
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Understanding Latent Tuberculosis: A Moving Target
2010
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Conditional stability of T cells
2010 StandoutNatureNobel
Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
2010
The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains ofMycobacterium tuberculosisin Mice
2001
Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells
2008
STAT1 Regulates IFN-αβ- and IFN-γ-Dependent Control of Infection withChlamydia pneumoniaeby Nonhemopoietic Cells
2006
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
2008
Bacillus Calmette Guerin Vaccination of Human Newborns Induces a Specific, Functional CD8+ T Cell Response
2006
The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis
2005
Cell-Mediated Immune Responses in Tuberculosis
2009 Standout
Impact of interferon-γ on hematopoiesis
2014
Correlates of Protection Induced by Vaccination
2010 Standout
Type I Interferons Increase Host Susceptibility to Trypanosoma cruzi Infection
2011
Temporal and Spatial Arrangement of Lymphocytes within Lung Granulomas Induced by Aerosol Infection withMycobacterium tuberculosis
2001
Works of John E. Pearl being referenced
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
2006
IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN-γ Responses if IL-12p70 Is Available
2005
Cutting Edge: T-bet and IL-27R Are Critical for In Vivo IFN-γ Production by CD8 T Cells during Infection
2008
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
2007
Inflammation and Lymphocyte Activation during Mycobacterial Infection in the Interferon-γ-Deficient Mouse
2001
CD8- and CD95/95L-Dependent Mechanisms of Resistance in Mice with Chronic Pulmonary Tuberculosis
2001
Cutting Edge: IFN-γ Regulates the Induction and Expansion of IL-17-Producing CD4 T Cells during Mycobacterial Infection
2006
Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control ofMycobacterium tuberculosisin the Murine Lung
2000
ESAT-6-specific CD4 T cell responses to aerosolMycobacterium tuberculosisinfection are initiated in the mediastinal lymph nodes
2008
Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFNγ-inducible fibrinogen-like protein 2
2004
Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rβ1 isoform that enhances DC migration
2010
Gamma Interferon-Induced T-Cell Loss in VirulentMycobacterium aviumInfection
2005
IL-27 Signaling Compromises Control of Bacterial Growth in Mycobacteria-Infected Mice
2004