Citation Impact
Citing Papers
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
2004 StandoutScience
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin
2020
HIV DNA Integration
2012
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
1990
Familial gastrointestinal stromal tumor with hyperpigmentation: Association with a germline mutation of the c-kit gene
2001
Melanotropic activity of gamma MSH peptides in melanoma cells
1992
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
The Drosophila EGF receptor homolog (DER) gene is allelic to faint little ball, a locus essential for embryonic development
1989
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.
1993
Steel locus defines new multipotent growth factor
1990
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila
1991 StandoutNobel
Kinetic Analysis of HIV-1 Early Replicative Steps in a Coculture System
1994
c‐kit proto‐oncogene exon 8 in‐frame deletion plus insertion mutations in acute myeloid leukaemia
1999
Integration of Retroviral DNA
1990
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap
2000 StandoutNobel
PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
2001
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis
2005
c‐kit Gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors
2003
Monoclonal Antibodies against HIV Type 1 Integrase: Clues to Molecular Structure
1994
In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development.
1991
Familial gastrointestinal stromal tumors associated with dysphagia and novel type germline mutation of KIT gene
2002
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
1993 StandoutNobel
Gain-of-function mutation at the extracellular domain of KIT in gastrointestinal stromal tumours
2001
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast
1989 StandoutNatureNobel
c‐kit point mutation of extracellular domain in patients with myeloproliferative disorders
1995
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
1990
c-Kit Point mutation in patients with myeloproliferative disorders
1997
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
1990 Standout
A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock
2001 StandoutNobel
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
1988 Nature
Stem cell factor (SCF), a novel hematopoietic growth factor and ligand for c-kit tyrosine kinase receptor, maps on human chromosome 12 between 12q14.3 and 12qter
1991
Leptin and the regulation of body weight in mammals
1998 StandoutNature
The biology of stem cell factor and its receptor C-kit
1999
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Early signaling pathways activated by c-Kit in hematopoietic cells
1999
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
Sequences of the 5′ portion of the humanc-sisgene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences
1987
Growth factors: Mechanism of action and relation to oncogenes
1984
Triplex-mediated inhibition of HIV DNA integration in vitro.
1994
Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C.
1994
Cellular Oncogenes and Multistep Carcinogenesis
1983 Science
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1.
1991 StandoutNobel
The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family.
1989
Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase
2003
Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region
2003
Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes
1989 Science
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
ret transforming gene encodes a fusion protein homologous to tyrosine kinases.
1987
cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity.
1987
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
1985 StandoutNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Molecular Basis of Human Piebaldism
1994
Stem Cell Factor and Hematopoiesis
1997
W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesis
1993
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
2000
Understanding the Dose-Effect Relationship
1981
Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene.
1986 StandoutNobel
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Impact of host cell line choice on glycan profile
2017
Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor
2000
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Biology of Gastrointestinal Stromal Tumors
2004 Standout
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries.
1988
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation
1994
Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcoma
1984 Nature
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.
1989
trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.
1989
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors
1998 StandoutScience
c-kit protein, a transmembrane kinase: identification in tissues and characterization.
1988
β-Peptides: From Structure to Function
2001 Standout
Full publication of results initially presented in abstracts
2007 Standout
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.
1987
Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors.
2003
Stem Cell Factor and Hematopoiesis
1997
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
1986 Nature
Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis.
1991
Both substrate and target oligonucleotide sequences affect in vitro integration mediated by human immunodeficiency virus type 1 integrase protein produced in Saccharomyces cerevisiae
1992 Nobel
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
1996
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus
1983 Nature
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines
1995
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
1987 StandoutNobel
Growth Factors and Cancer
1991 StandoutScience
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues
1994
High-frequency transduction of c-erbB in avian leukosis virus-induced erythroblastosis
1985
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis
1993
p145, a Protein with Associated Tyrosine Kinase Activity in a Human Gastric Carcinoma Cell Line
1988
Casein kinase Iɛ in the Wnt pathway: Regulation of β-catenin function
1999
A Novel Putative Tyrosine Kinase Receptor Encoded by the eph Gene
1987 Science
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Phospholipase C-gamma, a substrate for PDGF receptor kinase, is not phosphorylated on tyrosine during the mitogenic response to CSF-1.
1989
Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts.
1988
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
1988 StandoutNobel
Peptoid Polymers: A Highly Designable Bioinspired Material
2013
Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA.
1991
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
The biology of platelet-derived growth factor
1986 Standout
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism.
1991
Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors.
1988
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice
2002 StandoutNobel
Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein
1989
Works of John E. Murphy being referenced
Lipitoids — novel cationic lipids for cellular delivery of plasmid DNA in vitro
1998
Expression of Human Coagulation Factor VIII in a Human Hybrid Cell Line, HKB11
2006
Mutational Analysis of the Sequences at the Termini of the Moloney Murine Leukemia Virus DNA Required for Integration
1993
γ3-Melanocyte-Stimulating Hormone Immunoreactivity Is a Component of the Neuroendocrine Response to Maximal Stress (Cardiac Arrest)*
1985
Global Substrate Profiling of Proteases in Human Neutrophil Extracellular Traps Reveals Consensus Motif Predominantly Contributed by Elastase
2013
Perceived value and outcomes of residency projects
2001
A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family
1986 Nature
Construction and analysis of deletion mutations in the U5 region of Moloney murine leukemia virus: effects on RNA packaging and reverse transcription
1989
A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo
1992
A combinatorial approach to the discovery of efficient cationic peptoid reagents for gene delivery
1998
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin
1997
THE EFFECT OF DOSAGE REGIMEN ON THE DIURETIC EFFICACY OF CHLOROTHIAZIDE IN HUMAN SUBJECTS
1961
The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration
1989
The Parodi-Irgens feline sarcoma virus and simian sarcoma virus have homologous oncogenes, but in different contexts of the viral genomes
1983