Citation Impact
Citing Papers
Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β
2016
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
The PI3K/AKT Pathway as a Target for Cancer Treatment
2015
The Influence of Chromosomal Location on the Expression of Two Transgenes in Mice
1999 StandoutNobel
Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats
1999
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Hypoxic Regulation of Lactate Dehydrogenase A
1995 StandoutNobel
5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in aplysia sensory neurons
1989 StandoutNobel
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
1987 Standout
Links between metabolism and cancer
2012
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Selection and Analysis of a Mutant Cell Line Defective in the Hypoxia-inducible Factor-1 α-Subunit (HIF-1α)
1998 StandoutNobel
Phosphorylated CREB binds specifically to the nuclear protein CBP
1993 StandoutNature
Protein folding in the cell
1992 StandoutNature
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
1989 Standout
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling
1995 Standout
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy
2015
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Oncogenes and signal transduction
1991 Standout
MIF as a glucocorticoid-induced modulator of cytokine production
1995 StandoutNature
CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors
2014
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting
2014
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 StandoutNatureNobel
Topoisomerase I Interaction with SV4O DNA in the presence and absence of camptothecin
1988 StandoutNobel
Novel marine alkaloids from the tunicate Eudistoma sp. are potent regulators of cellular growth and differentiation and affect cAMP‐mediated processes
1993
AKT/PKB Signaling: Navigating the Network
2017 Standout
Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
2009 StandoutNobel
The PI3K Pathway in Human Disease
2017 Standout
Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons
1993 StandoutNobel
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
1994 Standout
Direct selection of hepatoma cell variants deficient in ?1-antitrypsin gene expression
1992
The phosphoinositide 3-kinase pathway and therapy resistance in cancer
2015
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
1993 StandoutNature
REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSION
1997
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
1984
Extinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway.
1993 StandoutNobel
cAMP stimulates transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase in rat liver nuclei.
1982
Hydrazine sulfate protects D-galactosamine-sensitized mice against endotoxin and tumor necrosis factor/cachectin lethality: evidence of a role for the pituitary.
1991
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Antarlides: A New Type of Androgen Receptor (AR) Antagonist that Overcomes Resistance to AR‐Targeted Therapy
2016
A C-terminal signal prevents secretion of luminal ER proteins
1987 Standout
Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver.
1992
Enzalutamide for the Treatment of Prostate Cancer: Results and Implications of the AFFIRM Trial
2014
Tse-2: a trans-dominant extinguisher of albumin gene expression in hepatoma hybrid cells.
1989
Characterization of the phosphoenolpyruvate carboxykinase (GTP) promoter-regulatory region. II. Identification of cAMP and glucocorticoid regulatory domains.
1986
Cyclic AMP stabilizes the mRNA for phosphoenolpyruvate carboxykinase (GTP) against degradation.
1988
Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin.
1991 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Identification of multiple protein binding domains in the promoter-regulatory region of the phosphoenolpyruvate carboxykinase (GTP) gene
1989
Nucleotide sequence of the putative regulatory region of mouse lactate dehydrogenase-A gene
1986
DNA damage promotes jumping between templates during enzymatic amplification.
1990 StandoutNobel
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Tse-2: a trans-Dominant Extinguisher of Albumin Gene Expression in Hepatoma Hybrid Cells
1989
Characterization of the cAMP responsive elements from the genes for the alpha-subunit of glycoprotein hormones and phosphoenolpyruvate carboxykinase (GTP). Conserved features of nuclear protein binding between tissues and species.
1988
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
1993 StandoutNobel
Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene
1987
Cyclic AMP regulation of lactate dehydrogenase. Isoproterenol and N6,O2-dibutyryl cyclic amp increase the rate of transcription and change the stability of lactate dehydrogenase a subunit messenger RNA in rat C6 glioma cells.
1983
Uncoating ATPase is a member of the 70 kilodalton family of stress proteins
1986 StandoutNobel
Cyclic AMP Regulation of Eukaryotic Gene Transcription by Two Discrete Molecular Mechanisms
1985 Science
Identification of c-fos sequences involved in induction by insulin and phorbol esters.
1988
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Eukaryotic Transcriptional Regulation and Chromatin-Associated Protein Phosphorylation by Cyclic AMP
1982 Science
Both subunits of rat liver ferritin are regulated at a translational level by iron induction
1986
Cyclic AMP and the induction of eukaryotic gene transcription.
1988
Differentiation of rat brown adipocytes during late foetal development: role of insulin-like growth factor I
1995
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
1989 StandoutNobel
Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.
1984
Two distinct pathways for cAMP-mediated down-regulation of the β2-adrenergic receptor
1989 StandoutNobel
Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.
1994
A mutation in the peroxisome proliferator-activated receptor γ-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice
2002
Multihormonal Regulation of Phosphoenolpyruvate Carboxykinase Gene Transcription
1986
Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.
1994
Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.
1987
Insulin-like growth factor I and insulin induce adipogenic-related gene expression in fetal brown adipocyte primary cultures
1996
A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.
1990 StandoutNobel
Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice.
1990
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Targeted Disruption of the Mouse Topoisomerase I Gene by Camptothecin Selection
1996 StandoutNobel
The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice
1999
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Circumventing Cancer Drug Resistance in the Era of Personalized Medicine
2012
Coupling of Hormonal Stimulation and Transcription via the Cyclic AMP-Responsive Factor CREB Is Rate Limited by Nuclear Entry of Protein Kinase A
1993 StandoutNobel
Biochemical characterization of the 94- and 78-kilodalton glucose-regulated proteins in hamster fibroblasts.
1984
Cloning of the cDNA for the human beta 1-adrenergic receptor.
1987 StandoutNobel
Works of John E. Monahan being referenced
An F876L Mutation in Androgen Receptor Confers Genetic and Phenotypic Resistance to MDV3100 (Enzalutamide)
2013
Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms
2011
Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat.
1983
Identification of a DNA clone to phosphoenolpyruvate carboxykinase (GTP) from rat cytosol. Alterations in phosphoenolpyruvate carboxykinase RNA levels detectable by hybridization.
1981
Rapid changes in the concentration of phosphoenolpyruvate carboxykinase mRNA in rat liver and kidney. Effects of insulin and cyclic AMP.
1982