Citation Impact
Citing Papers
Monitoring protein stability and aggregation in vivo by real-time fluorescent labeling
2003
SPDI: data model for variants and applications at NCBI
2019
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Tracking of Quantum Dot-labeled CFTR Shows Near Immobilization by C-Terminal PDZ Interactions
2006
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
2003 Standout
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
The UK Biobank resource with deep phenotyping and genomic data
2018 StandoutNature
Monomeric CFTR in Plasma Membranes in Live Cells Revealed by Single Molecule Fluorescence Imaging
2008
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity
2010 StandoutNobel
The Influence of Genetics on Cystic Fibrosis Phenotypes
2012
SIFT web server: predicting effects of amino acid substitutions on proteins
2012 Standout
The Retinal Pigment Epithelium in Visual Function
2005 Standout
International Union of Pharmacology. XLIX. Nomenclature and Structure-Function Relationships of Transient Receptor Potential Channels
2005 StandoutNobel
Frequent Occurrence of the CFTRIntron 8 (TG)n 5T Allele in Men withCongenital Bilateral Absence of the Vas Deferens
1995
Cystic fibrosis mutations for p.F508del compound heterozygotes predict sweat chloride levels and pancreatic sufficiency
2011
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF
2000
Cystic fibrosis
2016 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
Cystic fibrosis transmembrane conductance regulator in teleost fish
2002
Denufosol: A review of studies with inhaled P2Y2 agonists that led to Phase 3
2008
Genotype and Phenotype in Cystic Fibrosis
2000
A Novel Protein Complex Linking the δ2 Glutamate Receptor and Autophagy
2002
Effect of genotype on phenotype and mortality in cystic fibrosis: a retrospective cohort study
2003
Defective autophagy leads to cancer
2003
Building and breeding molecules to spy on cells and tumors
2004 StandoutNobel
Modifier genes in Mendelian disorders: the example of cystic fibrosis
2010
A Combined Analysis of the Cystic Fibrosis Transmembrane Conductance Regulator: Implications for Structure and Disease Models
2001
Database resources of the National Center for Biotechnology Information: update
2003 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
ΔF508 CFTR protein expression in tissues from patients with cystic fibrosis
1999
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice
2009
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
2001
A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation
2011 Standout
Neuroligins Determine Synapse Maturation and Function
2006 StandoutNobel
New insights into cystic fibrosis: molecular switches that regulate CFTR
2006
Bacterial biofilms: from the Natural environment to infectious diseases
2004 Standout
G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+ Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction
1999 StandoutNobel
Processing of CFTR: Traversing the cellular maze—How much CFTR needs to go through to avoid cystic fibrosis?
2005
International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels
2003 StandoutNobel
Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus Report
2008
Autophagy in the Pathogenesis of Disease
2008 Standout
Laboratory standards and guidelines for population-based cystic fibrosis carrier screening
2001
Intestinal mucosal barrier function in health and disease
2009 Standout
Phase 2 Randomized Safety and Efficacy Trial of Nebulized Denufosol Tetrasodium in Cystic Fibrosis
2007
Autophagy in Human Health and Disease
2013 Standout
G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95
2002 StandoutNobel
PDZ domains – glue and guide
2003
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Cystic fibrosis genetics: from molecular understanding to clinical application
2014 Standout
Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations
1995
A Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Generates a Novel Internalization Sequence and Enhances Endocytic Rates
2003
CFTR Genotype as a Predictor of Prognosis in Cystic Fibrosis
2006
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
2018 Standout
Efficacy and safety of ivacaftor in patients with cystic fibrosis who have an Arg117His-CFTR mutation: a double-blind, randomised controlled trial
2015
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships
2008
The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste
2004 Standout
Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling
2001 StandoutNobel
Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders
2008
Autophagy in cell death: an innocent convict?
2005 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Solution Structure of the RIM1α PDZ Domain in Complex with an ELKS1b C-terminal Peptide
2005 StandoutNobel
Cysteine String Protein Interacts with and Modulates the Maturation of the Cystic Fibrosis Transmembrane Conductance Regulator
2002
Seven-transmembrane receptors
2002 StandoutNobel
Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity
2000 StandoutNobel
β1-Adrenergic Receptor Association with PSD-95
2000 StandoutNobel
Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer
2005 StandoutNobel
The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin
2004
Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens
1995 Standout
Parathyroid hormone treatment induces dissociation of type IIa Na+-Pi cotransporter-Na+/H+ exchanger regulatory factor-1 complexes
2005
Validating therapeutic targets through human genetics
2013
Airway Inflammation and Infection in Congenital Bilateral Absence of the Vas Deferens
2003
Transport Protein Trafficking in Polarized Cells
2003
Is congenital bilateral absence of vas deferens a primary form of cystic fibrosis? Analyses of the CFTR gene in 67 patients.
1995
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA
2000
Implications of Rewiring Bacterial Quorum Sensing
2007 StandoutNobel
Molecular Structure and Physiological Function of Chloride Channels
2002
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins
2002 StandoutNobel
Role of CFTR in Airway Disease
1999
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Single-Molecule Spectroscopy and Imaging of Biomolecules in Living Cells
2010 StandoutNobel
Correlation between Genotype and Phenotype in Patients with Cystic Fibrosis
1993
Heptahelical Receptor Signaling: Beyond the G Protein Paradigm
1999 StandoutNobel
Genetic Variation and Clinical Heterogeneity in Cystic Fibrosis
2011
Trafficking of G Protein–Coupled Receptors
2006 StandoutNobel
Lung Infections Associated with Cystic Fibrosis
2002 Standout
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction
2001
Physiology of Microglia
2011 Standout
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of John E. Mickle being referenced
CLINICAL IMPLICATIONS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MUTATIONS
1998
A PDZ-interacting domain in CFTR is an apical membrane polarization signal
1999
A Golgi-associated PDZ Domain Protein Modulates Cystic Fibrosis Transmembrane Regulator Plasma Membrane Expression
2002
A mutation in the cystic fibrosis transmembrane conductance regulator gene associated with elevated sweat chloride concentrations in the absence of cystic fibrosis
1998
Aggregation of Misfolded Proteins Can Be a Selective Process Dependent upon Peptide Composition
2002
GENOTYPE-PHENOTYPE RELATIONSHIPS IN CYSTIC FIBROSIS
2000
Pulmonary Function and Clinical Observations in Men With Congenital Bilateral Absence of the Vas Deferens
1996
Effects of Cystic Fibrosis and Congenital Bilateral Absence of the Vas Deferens–Associated Mutations on Cystic Fibrosis Transmembrane Conductance Regulator–Mediated Regulation of Separate Channels
2000
The PDZ-interacting Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is Required for Functional Expression in the Apical Plasma Membrane
2000
A mutation in CFTR produces different phenotypes depending on chromosomal background
1993
A PDZ-binding motif is essential but not sufficient to localize the C terminus of CFTR to the apical membrane
2001