Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Asymmetric Counteranion‐Directed Catalysis: Concept, Definition, and Applications
2012 StandoutNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
2009 StandoutNature
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold
2005
Asymmetric Organocatalytic Cascade Reactions with α‐Substituted α,β‐Unsaturated Aldehydes
2009
Dynamic imine chemistry
2012 StandoutNobel
Can small animal imaging accelerate drug development?
2002
Efficient Friedel–Crafts alkylation of indoles and pyrrole with enones and nitroalkene in water
2006
A Powerful Chiral Counteranion Motif for Asymmetric Catalysis
2009 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Emil Knoevenagel and the Roots of Aminocatalysis
2010 StandoutNobel
A Highly Enantioselective Overman Rearrangement through Asymmetric Counteranion‐Directed Palladium Catalysis
2011 StandoutNobel
Receptors for 5-Hydroxytryptamine: Current perspectives on classification and nomenclature
1994
Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: identification and optimisation of substituted 2,4-bis anilino pyrimidines
2003
The Catalytic Asymmetric Knoevenagel Condensation
2011 StandoutNobel
Organocatalytic Enantioselective Decarboxylative Aldol Reaction of Malonic Acid Half Thioesters with Aldehydes
2013 StandoutNobel
Activation of Carboxylic Acids in Asymmetric Organocatalysis
2014 StandoutNobel
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Tandem inverse-electron-demand hetero-/retro-Diels–Alder reactions for aromatic nitrogen heterocycle synthesis
2012
Creating an α7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein
2011
Serotonin receptors: Subtypes, functional responses and therapeutic relevance
1995
The induction of pain: an integrative review
1999
The structural basis of function in Cys-loop receptors
2010
A Catalytic Asymmetric 6 π Electrocyclization: Enantioselective Synthesis of 2‐Pyrazolines
2009 StandoutNobel
Chiral Primary Amine Catalyzed Enantioselective Protonation via an Enamine Intermediate
2011
Catalytic Asymmetric Hydroperoxidation of α,β‐Unsaturated Ketones: An Approach to Enantiopure Peroxyhemiketals, Epoxides, and Aldols
2008 StandoutNobel
Organocatalytic enantioselective indole alkylations of α,β-unsaturated ketones
2007
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
2009
Enantioselective Friedel–Crafts Reactions in Water Using a DNA‐Based Catalyst
2009 StandoutNobel
The advent and development of organocatalysis
2008 StandoutNature
DNA‐Based Catalytic Enantioselective Michael Reactions in Water
2007 StandoutNobel
Organocatalytic strategies for the asymmetric functionalization of indoles
2010
Are GPCRs Still a Source of New Targets?
2013
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Lewis Base Catalysis in Organic Synthesis
2008
Organocatalytic Synthesis of Drugs and Bioactive Natural Products
2007
The Activation of Carboxylic Acids via Self-Assembly Asymmetric Organocatalysis: A Combined Experimental and Computational Investigation
2016 StandoutNobel
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
2011 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
The Role of the Indole in Important Organocatalytic Enantioselective Friedel-Crafts Alkylation Reactions
2009
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Diversity‐Oriented Syntheses by Combining CuAAC and Stereoselective INCIC Reactions with Peptides
2017 StandoutNobel
Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles
2021 StandoutNobel
Seven Post-synthetic Covalent Reactions in Tandem Leading to Enzyme-like Complexity within Metal–Organic Framework Crystals
2016 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals
2012 StandoutNobel
Organocatalyzed Asymmetric Friedel–Crafts Reactions
2010
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Recent developments in indole ring synthesis—methodology and applications
2000 Standout
Iminium Catalysis
2007
Cooperative Reactivity in an Extended-Viologen-Based Cyclophane
2016 StandoutNobel
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Highly Enantioselective Michael Addition of Cyclic 1,3‐Dicarbonyl Compounds to α,β‐Unsaturated Ketones.
2007
7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa
2007
Katalytische Funktionalisierung von Indolen in einer neuen Dimension
2009
Solid-Phase Synthesis of 1,2-Diheterocyclic-Substituted (E)-Olefins from a Supported Selenium Resin
2005
Lewis‐Base‐Katalyse in der organischen Synthese
2008
Catalytic Asymmetric Friedel−Crafts Alkylation Reactions—Copper Showed the Way
2008
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
2017 StandoutNobel
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
The Cinchona Primary Amine-Catalyzed Asymmetric Epoxidation and Hydroperoxidation of α,β-Unsaturated Carbonyl Compounds with Hydrogen Peroxide
2013 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Unusual Amino Acids in Medicinal Chemistry
2016
Catalytic Asymmetric Epoxidation of α-Branched Enals
2010 StandoutNobel
Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of Primary Amines
2017 StandoutNobel
SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase
2006
Asymmetric Organocatalytic Cascade Reactions with α‐Substituted α,β‐Unsaturated Aldehydes
2009
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Claisen Rearrangement over the Past Nine Decades
2004
Highly Enantioselective Michael Addition of Cyclic 1,3-Dicarbonyl Compounds to α,β-Unsaturated Ketones
2007
The state of the art in asymmetric induction: the aldol reaction as a case study
2009
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction Using a Molecular Motor
2011 StandoutScienceNobel
Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists,
2005
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Catalytic Asymmetric Conjugate Addition of Indolizines to α,β‐Unsaturated Ketones
2017 StandoutNobel
Works of John E. Macor being referenced
Characterization of [3H]CP‐96,501 as a Selective Radioligand for the Serotonin 5‐HT1B Receptor: Binding Studies in Rat Brain Membranes
1992
Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists
2013
Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines
2016
Serendipitous oxidation product of BIBN4096BS: A potent CGRP receptor antagonist
2014
Comparative Biotransformation of Pyrazinone-Containing Corticotropin-Releasing Factor Receptor-1 Antagonists: Minimizing the Reactive Metabolite Formation
2009
The in vivo pharmacological profile of a 5‐HT1 receptor agonist, CP‐122, 288, a selective inhibitor of neurogenic inflammation
1995
β-Alanine dipeptides as MC4R agonists
2003
Synthesis and structure–activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists
2010
The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 1
2012
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist
2001
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1*) agonist and rotationally restricted phenolic analog of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole
1990
An unusually facile diels-alder reaction with novel 6-alkylthio derivatives of 1,2,4-triazine
1985
Discovery of (5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): An Oral Calcitonin Gene-Related Peptide (CGRP) Antagonist in Clinical Trials for Treating Migraine
2012
Neutral acylation (protection) of the indole nitrogen: A simple synthesis of indole-1-carboxylates, indole-1-thiocarboxylates and indole-1-carboxamides
1999
One-pot synthesis of homotryptamines from indoles
2004
Intramolecular Diels-Alder reactions of 1,2,4-triazines. A facile synthesis of thieno[2,3-b]pyridines and 3,4-dihydro-2H-thiopyrano[2,3-b]pyridines
1987
Synthesis and Use of 5-Vinyl-1,2,4-oxadiazoles as Michael Acceptors. A Rapid Synthesis of the Potent Muscarinic Agonist L-670,548
1996
Discovery of Tyrosine-Based Potent and Selective Melanocortin-1 Receptor Small-Molecule Agonists with Anti-inflammatory Properties
2003
Annual Reports in Medicinal Chemistry
2002
Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde
2005
A Chiral Synthesis of (−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘- oxazolidin-2‘-one]: A Conformationally Restricted Analogue of Acetylcholine That Is a Potent and Selective α7 Nicotinic Receptor Agonist
2004
An improved synthesis of the unique anti-migraine agent CP-122,288: A bromine atom passenger in an intramolecular Heck reaction
1996
Discovery of (R)-4-(8-Fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): A Potent Antagonist of the Human Calcitonin Gene-Related Peptide Receptor for Migraine with Rapid and Efficient Intranasal Exposure
2008
Studies towards understanding the mechanism of the unusual rearrangement of certain 5-propargyloxyindoles
2000
The synthesis of a conformationally restricted analog of the anti-migraine drug sumatriptan
1992