Standout Papers
- Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. (2000)
- Graft-versus-host disease (2009)
Citation Impact
Citing Papers
High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning
2010
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3 + CD25 + CD4 + regulatory T cells
2005 StandoutNobel
Sequential Binding of Cytosolic Phox Complex to Phagosomes through Regulated Adaptor Proteins: Evaluation Using the Novel Monomeric Kusabira-Green System and Live Imaging of Phagocytosis
2008
Low Exposure Busulfan Conditioning to Achieve Sufficient Multilineage Chimerism in Patients with Severe Combined Immunodeficiency
2019
Proceedings from the National Cancer Institute’s Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part III. Prevention and Treatment of Relapse after Allogeneic Transplantation
2013
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
Rac GTPase Isoform-specific Regulation of NADPH Oxidase and Chemotaxis in Murine Neutrophils in Vivo
2004
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Application of metagenomics in the human gut microbiome
2015
IL-6 Blockade Attenuates the Development of Murine Sclerodermatous Chronic Graft-Versus-Host Disease
2012
Rac1 and Rac2 GTPases in haematopoiesis
2004
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Mucin-1 is expressed on dendritic cells, both in vitro and in vivo
2004
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Cancer Metastasis: Building a Framework
2006 Standout
The Human Intestinal Microbiome in Health and Disease
2016 Standout
The Principles of Engineering Immune Cells to Treat Cancer
2017
Targeted Radiotherapy With Submyeloablative Doses of 131I-MIBG Is Effective for Disease Palliation in Highly Refractory Neuroblastoma
2003
Neuroblastoma: biological insights into a clinical enigma
2003 Standout
Cancer immunotherapy via dendritic cells
2012 Standout
Trial watch
2013
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
2011 Standout
Chimeric antigen receptors: driving immunology towards synthetic biology
2016
Metazoan MicroRNAs
2018 Standout
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Etanercept (Enbrel) administration for idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation
2002
The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer
2015
Cancer immunotherapy: moving beyond current vaccines
2004 Standout
Mammalian Rho GTPases: new insights into their functions from in vivo studies
2008 Standout
CARs on Track in the Clinic
2011
Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors
2013
Rac2 Specificity in Macrophage Integrin Signaling
2003
Can graft-versus-leukemia reactivity be dissociated from graft-versus-host disease?
2007
The Rheb family of GTP-binding proteins
2004
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Cancer vaccines: between the idea and the reality
2003
Sickle-cell disease
2010 Standout
Hematopoietic Stem-Cell Transplantation
2006 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Neuroblastoma
2007 Standout
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Tocilizumab for the Treatment of Steroid Refractory Graft-versus-Host Disease
2011
Regulation of neutrophil function by Rac GTPases
2003
The First 1000 Dendritic Cell Vaccinees
2003
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
2012
Preparation of Clinical‐Grade Recombinant Canarypox–Human Immunodeficiency Virus Vaccine–Loaded Human Dendritic Cells
2002 StandoutNobel
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
2004
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Dendritic cell immunotherapy: mapping the way
2004
Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease
2010 Standout
Tumor response and toxicity with multiple infusions of high dose 131I‐MIBG for refractory neuroblastoma
2004
Rho GTPases and Regulation of Hematopoietic Stem Cell Localization
2008
The Interleukin-1 Family: Back to the Future
2013
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
2003
DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic Cells
2003 StandoutNobel
A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity
2008 StandoutNobel
Rac2 Regulates Neutrophil Chemotaxis, Superoxide Production, and Myeloid Colony Formation through Multiple Distinct Effector Pathways
2005
PD-1– and CTLA-4–Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
2013
Acute Myeloid Leukemia
2015 Standout
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
2011
Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft-Versus-Host Disease
2011
Chemoattractant-Stimulated Rac Activation in Wild-Type and Rac2-Deficient Murine Neutrophils: Preferential Activation of Rac2 and Rac2 Gene Dosage Effect on Neutrophil Functions
2002
RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells
2004
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
2012 StandoutNobel
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
2007
A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation
2005
RhoG Regulates the Neutrophil NADPH Oxidase
2006
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
2001
Correlation of Early Metastatic Response by123I-Metaiodobenzylguanidine Scintigraphy With Overall Response and Event-Free Survival in Stage IV Neuroblastoma
2003
TNF Receptor-Associated Factor 6-Dependent CD40 Signaling Primes Macrophages to Acquire Antimicrobial Activity in Response to TNF-α
2005
An essential role for Rac1 in endothelial cell function and vascular development
2008
Hematologic Toxicity of High-Dose Iodine-131–Metaiodobenzylguanidine Therapy for Advanced Neuroblastoma
2004
Cytokine Storm
2020 Standout
Rac2-Deficient Hematopoietic Stem Cells Show Defective Interaction with the Hematopoietic Microenvironment and Long-Term Engraftment Failure
2005
Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns
2010
Chimeric Antigen Receptor Therapy
2018 Standout
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Impact of Metaiodobenzylguanidine Scintigraphy on Assessing Response of High-Risk Neuroblastoma to Dose-Intensive Induction Chemotherapy
2003
Rac2 Is an Essential Regulator of Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Response to Specific Signaling Pathways
2001
Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice
2014
In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination
2004 StandoutNobel
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Dose-escalated donor lymphocyte infusions following reduced intensity transplantation: toxicity, chimerism, and disease responses
2003
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Mature T cell responses are controlled by microRNA-142
2015
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Expansion of Melanoma-specific Cytolytic CD8+ T Cell Precursors in Patients with Metastatic Melanoma Vaccinated with CD34+ Progenitor-derived Dendritic Cells
2004
Neoantigens in cancer immunotherapy
2015 StandoutScience
Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles
2004
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Rac2 is critical for neutrophil primary granule exocytosis
2004
Rational approaches to human cancer immunotherapy
2003
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions
2003
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton
2006
Works of John E. Levine being referenced
Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease
2014
ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death
2013
EBMT−NIH−CIBMTR Task Force position statement on standardized terminology & guidance for graft-versus-host disease assessment
2018
Tacrolimus (FK506) and methotrexate as prophylaxis for acute graft-versus-host disease in pediatric allogeneic stem cell transplantation
2000
Implications of TNF-α in the pathogenesis and management of GVHD
2011
Unrelated Donor Cord Blood Transplantation for Children with Severe Sickle Cell Disease: Results of One Cohort from the Phase II Study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN)
2012
Graft-versus-host disease
2009 Standout
Donor leukocyte infusions in acute lymphocytic leukemia
2000
Graft-Versus-Host Disease and Graft-Versus-Leukemia After Donor Leukocyte Infusion
2006
Donor leukocyte infusions for multiple myeloma
2000
Cytokine-mobilized allogeneic peripheral blood stem cell transplants in children result in rapid engraftment and a high incidence of chronic GVHD
2000
Blood and Marrow Transplant Clinical Trials Network State of the Science Symposium 2007
2007
NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
2010
Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression.
2001
The impact of soluble tumor necrosis factor receptor etanercept on the treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation
2008
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.
2000 StandoutNobel
Prospective Trial of Chemotherapy and Donor Leukocyte Infusions for Relapse of Advanced Myeloid Malignancies After Allogeneic Stem-Cell Transplantation
2002
Prospective Trial of Chemotherapy and Donor Leukocyte Infusions for Relapse of Advanced Myeloid Malignancies After Allogeneic Stem-Cell Transplantation
2002
Pilot Study of Iodine-131–Metaiodobenzylguanidine in Combination With Myeloablative Chemotherapy and Autologous Stem-Cell Support for the Treatment of Neuroblastoma
2002
Lowered-intensity preparative regimen for allogeneic stem cell transplantation delays acute graft-versus-host disease but does not improve outcome for advanced hematologic malignancy
2003