Citation Impact
Citing Papers
Coordinated plant defense responses in Arabidopsis revealed by microarray analysis
2000 Standout
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides
2006
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
The role of FUS gene variants in neurodegenerative diseases
2014
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
2016 Standout
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Mdm2 promotes the rapid degradation of p53
1997 StandoutNature
p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53
1999
Proteins regulating Ras and its relatives
1993 StandoutNature
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
2009 Standout
β-Arrestin Is Crucial for Ubiquitination and Down-regulation of the Insulin-like Growth Factor-1 Receptor by Acting as Adaptor for the MDM2 E3 Ligase
2005 StandoutNobel
Regulation of p53 stability by Mdm2
1997 StandoutNature
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
1995 Nature
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
2001 StandoutNobel
p53 in growth control and neoplasia
1996
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
1994 StandoutNature
DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2
1997 Standout
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
2010
Reprogramming of human somatic cells to pluripotency with defined factors
2007 StandoutNature
Mendelian cytogenetics. Chromosome rearrangements associated with mendelian disorders.
1993
Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis
2015
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
TOR, a Central Controller of Cell Growth
2000 Standout
Lineage dependency and lineage-survival oncogenes in human cancer
2006
Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
2008
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
2015
Cells on chips
2006 StandoutNature
Stabilization of the MDM2 Oncoprotein by Interaction with the Structurally Related MDMX Protein
1999
Deficient Geranylgeranylation of Ram/Rab27 in Choroideremia
1995
Soft-Tissue Sarcomas in Adults
2005 Standout
Cell Death
2004 Standout
Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis
2010
A Chromatin-associated and Transcriptionally Inactive p53-Mdm2 Complex Occurs in mdm2 SNP309 Homozygous Cells
2005
Systemic dysregulation of TDP-43 binding microRNAs in amyotrophic lateral sclerosis
2013
Decoding ALS: from genes to mechanism
2016 StandoutNature
Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway
2000 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
2010
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
2010
Blinded by the Light: The Growing Complexity of p53
2009 Standout
cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein
1993 Nobel
Translational control of growth factor and proto-oncogene expression
1999
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
2007
Profilin 1 Associates with Stress Granules and ALS-Linked Mutations Alter Stress Granule Dynamics
2014
Regulation of the p53 Tumor Suppressor Protein
1999
Misregulated RNA processing in amyotrophic lateral sclerosis
2012
The MDM2 gene amplification database
1998
MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase varepsilon
2000
Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene product
1992 StandoutNobel
Translational control: the cancer connection
1999
Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis
2013
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
1998
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
2012
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
A functionally inactive p53 protein interatocarcinoma cells is activated by either DNA damage or cellular differentiation
1996
The Amyloid State of Proteins in Human Diseases
2012 Standout
The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor
2000 StandoutNobel
Connections between growth and the cell cycle
1998
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
2012 Standout
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
2006
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
1997
Evolution and Functions of Long Noncoding RNAs
2009 Standout
eIF4E expression in tumors: its possible role in progression of malignancies
1999
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1
2002
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001 Standout
The Roles of E6-AP and MDM2 in p53 Regulation in Human Papillomavirus-Positive Cervical Cancer Cells
2000
A catalogue of imprinted genes and parent-of-origin effects in humans and animals
1998
Mouse Double Minute 2 Associates with Chromatin in the Presence of p53 and Is Released to Facilitate Activation of Transcription
2006
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
The MDM2 Oncoprotein Binds Specifically to RNA through its RING Finger Domain
1996
Induction of apoptosis in HeLa cells by trans-activation-deficient p53.
1995
Retinal genetics: a nullifying effect for rhodopsin
1992
Whole-exome sequencing identifies a missense mutation in hnRNPA1 in a family with flail arm ALS
2016
Global response of Saccharomyces cerevisiae to an alkylating agent
1999
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Molecular Genetics and Cytogenetics of Sarcomas
1995
MDMX: a novel p53-binding protein with some functional properties of MDM2.
1996
The Origins of Medulloblastoma Subtypes
2008
TLRs and innate immunity
2008 StandoutNobel
Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis
2000 StandoutScience
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
2007
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Designing a nano-interface in a microfluidic chip to probe living cells: Challenges and perspectives
2006
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Cell type-specific inhibition of p53-mediated apoptosis by mdm2.
1996
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential.
1994
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Upstream Open Reading Frames as Regulators of mRNA Translation
2000
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage
1998
Works of John E. Landers being referenced
Genome complexity reduction for SNP genotyping analysis
2002
Identification of rare protein disulfide isomerase gene variants in amyotrophic lateral sclerosis patients
2015
Using high-throughput SNP technologies to study cancer
2006
Mutational analysis of TARDBP in neurodegenerative diseases
2009
Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain
1998
Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis
2011
A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, Nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts
2012
Analysis of hnRNPA1, A2/B1, and A3 genes in patients with amyotrophic lateral sclerosis
2013
Isolation of a candidate gene for choroideremia.
1992
Enhanced translation: a novel mechanism of mdm2 oncogene overexpression identified in human tumor cells.
1994
Physical and Functional Interaction between Wild-Type p53 and mdm2 Proteins
1994
Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort
2009
Physical and functional interaction between wild-type p53 and mdm2 proteins.
1994
RNA processing pathways in amyotrophic lateral sclerosis
2010
New VAPB deletion variant and exclusion of VAPB mutations in familial ALS
2008
Translational enhancement of mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein.
1997