Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Toxicities of chimeric antigen receptor T cells: recognition and management
2016
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion
2008 StandoutNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
MUC1 Vaccine for Individuals with Advanced Adenoma of the Colon: A Cancer Immunoprevention Feasibility Study
2012
The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
2014
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results
2012
Current and emerging systemic therapies for cutaneous metastatic melanoma
2019
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Chimeric Antigen Receptor (CAR)-Specific Monoclonal Antibody to Detect CD19-Specific T Cells in Clinical Trials
2013
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR
2012
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma
2008
Simplified process for the production of anti–CD19-CAR–engineered T cells
2013
Delivery of molecular and cellular medicine to solid tumors
1998
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Increasing tumor uptake of anticancer drugs with imatinib
2004
T cell profiling reveals high CD4+CTLA-4+ T cell frequency as dominant predictor for survival after Prostate GVAX/ipilimumab treatment
2012
The Principles of Engineering Immune Cells to Treat Cancer
2017
Delivery of molecular and cellular medicine to solid tumors1PII of original article: S0169-409X(97)00027-6. The article was originally published in Advanced Drug Delivery Reviews 26 (1997) 71–90.1
2001
Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18
2017
Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps
2015
Beyond humanization and de-immunization: tolerization as a method for reducing the immunogenicity of biologics
2013
Adoptive immunotherapy for cancer: harnessing the T cell response
2012
The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design
2006
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Central nervous system control of food intake
2000 StandoutNature
CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients
2011
Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts
1996
Delivery of molecular and cellular medicine to solid tumors
2012
High interstitial fluid pressure — an obstacle in cancer therapy
2004 Standout
Treating B-cell cancer with T cells expressing anti-CD19 chimeric antigen receptors
2013
Engineering CAR-T cells: Design concepts
2015
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
2018
Origin and physiological roles of inflammation
2008 StandoutNature
Therapeutic vaccines for cancer: an overview of clinical trials
2014
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial
2014 Standout
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
New Cell Sources for T Cell Engineering and Adoptive Immunotherapy
2015
Adoptive-cell-transfer therapy for the treatment of patients with cancer
2003
Therapeutic T cell engineering
2017 Nature
Chimeric antigen receptor T-cell therapies for lymphoma
2017
Transport of Molecules, Particles, and Cells in Solid Tumors
1999
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Inhibition of initiator‐induced SV40 gene amplification in SV40‐transformed Chinese hamster cells by infection with a defective parvovirus
1983 StandoutNobel
What Is the Role of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade in Patients with Metastatic Melanoma?
2009
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
2011
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
The Steroid and Thyroid Hormone Receptor Superfamily
1988 StandoutScience
The B7 Family and Cancer Therapy: Costimulation and Coinhibition
2007 StandoutNobel
Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft.
1993
Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/lymphoma
2012 StandoutNobel
Changes in Plasma Leptin during the Treatment of Diabetic Ketoacidosis
1999
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
2012
Ion-dependent protein–surface interactions from intrinsic solvent response
2021 StandoutNobel
Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma: A Multicenter Phase II Study
2012
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
2015
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Promoter Elements of Genes Coding for Proteins and Modulation of Transcription by Estrogens and Progesterone
1984
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.
2002
Chimeric Antigen Receptor Therapy
2018 Standout
Viruses in Human Cancers
1991 StandoutScienceNobel
Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications.
1999
T cells expressing an anti–B-cell maturation antigen chimeric antigen receptor cause remissions of multiple myeloma
2016
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
Sequences controlling in vitro transcription of SV40 promoters.
1983
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma
2010
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Tandem Native Mass-Spectrometry on Antibody–Drug Conjugates and Submillion Da Antibody–Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector
2015
Transcriptional selectivity of viral genes in mammalian cells
1986
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells
2010 StandoutNobel
The Future Is Now: Chimeric Antigen Receptors as New Targeted Therapies for Childhood Cancer
2012
HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions
1984 StandoutNobel
IL-2: The First Effective Immunotherapy for Human Cancer
2014
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Ipilimumab in Combination With Paclitaxel and Carboplatin As First-Line Treatment in Stage IIIB/IV Non–Small-Cell Lung Cancer: Results From a Randomized, Double-Blind, Multicenter Phase II Study
2012
Protein Assembly: Versatile Approaches to Construct Highly Ordered Nanostructures
2016
Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen.
1984
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Lenalidomide efficacy in activated B ‐cell‐like subtype diffuse large B ‐cell lymphoma is dependent upon IRF 4 and cereblon expression
2012
Interstitial fluid pressure predicts survival in patients with cervix cancer independent of clinical prognostic factors and tumor oxygen measurements.
2001
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Antibody Fusion Proteins: Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox
2011
Epidemiology, Treatment, and Prevention of Human T-Cell Leukemia Virus Type 1-Associated Diseases
2010
Works of John E. Janik being referenced
Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma
2009
Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis
2017
Endocrine Effects of IL-1α and β Administered in a Phase I Trial to Patients with Advanced Cancer
1996
Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer.
1998
Progress on new vaccine strategies against chronic viral infections
2004
The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies.
1992
Herpes Simplex Virus Types 1 and 2 Completely Help Adenovirus-Associated Virus Replication
1981
Vaccination With Patient-Specific Tumor-Derived Antigen in First Remission Improves Disease-Free Survival in Follicular Lymphoma
2011
A Pilot Study of CTLA-4 Blockade after Cancer Vaccine Failure in Patients with Advanced Malignancy
2007
Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients: changes during treatment.
1993
Interleukin 1α Increases Serum Leptin Concentrations in Humans
1997
Site-specific base substitution and deletion mutations that enhance or suppress transcription of the SV40 major late RNA
1982
Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia
2012
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP
2010
Brentuximab Vedotin (SGN-35)
2011
Progress on new vaccine strategies against chronic viral infections
2004
Preclinical and phase I clinical trial of blockade of IL-15 using Mikβ1 monoclonal antibody in T cell large granular lymphocyte leukemia
2005
Definition, Prognostic Factors, Treatment, and Response Criteria of Adult T-Cell Leukemia-Lymphoma: A Proposal From an International Consensus Meeting
2008
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
2010