Citation Impact
Citing Papers
Targeting Mitochondrial Oxidative Metabolism in Melanoma Causes Metabolic Compensation through Glucose and Glutamine Utilization
2014
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Oxidative Stress
2017 Standout
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
Linking Crystallographic Model and Data Quality
2012 Science
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
2020 StandoutScience
Generation of protein-derived redoxcofactors by posttranslational modification
2010
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
2014 Standout
Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells
2017
Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
2019
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
2014
Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
2010
Skeletal Muscle Fatigue: Cellular Mechanisms
2008 Standout
MYC on the Path to Cancer
2012 Standout
Specificity of amino acid regulated gene expression: analysis of genes subjected to either complete or single amino acid deprivation
2008
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cofactor-dependent maturation of mammalian sulfite oxidase links two mitochondrial import pathways
2012
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
2020
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
2016
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation
2021
Hallmarks of aging: An expanding universe
2023 Standout
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis
2020
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
2015
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
Golgi stress mediates redox imbalance and ferroptosis in human cells
2018
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
2015
Amino acids: metabolism, functions, and nutrition
2009 Standout
The absorption of orally supplied β-alanine and its effect on muscle carnosine synthesis in human vastus lateralis
2006
The nexus of chromatin regulation and intermediary metabolism
2013 Nature
Strategies for in vivo imaging of enzyme activity: an overview and recent advances
2011
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function
2016
Effect of Beta-Alanine and Carnosine Supplementation on Muscle Contractility in Mice
2013
A highly selective turn-on near-infrared fluorescent probe for hydrogen sulfide detection and imaging in living cells
2012
Sirtuins and the Metabolic Hurdles in Cancer
2015
Coming of age: molecular drivers of aging and therapeutic opportunities
2013
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Drugs that modulate aging: the promising yet difficult path ahead
2013
Structural and energetic basis of folded-protein transport by the FimD usher
2013 StandoutNatureNobel
Better models by discarding data?
2013
Dynamics and functions of lipid droplets
2018 Standout
Influence of β-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity
2006
Amino acid requirements in humans: with a special emphasis on the metabolic availability of amino acids
2009
NAD+ homeostasis in health and disease
2020
Amino acids and gaseous signaling
2009
An ICT-based strategy to a colorimetric and ratiometric fluorescence probe for hydrogen sulfide in living cells
2012
Crosstalk between Components of Circadian and Metabolic Cycles in Mammals
2011
The role of senescent cells in ageing
2014 StandoutNature
The role of aberrant mitochondrial bioenergetics in diabetic neuropathy
2012
Caloric restriction mimetics: towards a molecular definition
2014
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
2017
Geroscience: Linking Aging to Chronic Disease
2014 Standout
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Dendritic cell metabolism
2014
The Hallmarks of Aging
2013 Standout
Comparison of the metabolic and ventilatory response to hypoxia and H2S in unsedated mice and rats
2009
Sirtuin Catalysis and Regulation
2012
ATF4-dependent transcription mediates signaling of amino acid limitation
2009
Recent progress in the development of near-infrared fluorescent probes for bioimaging applications
2013 Standout
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
2020 Standout
Development and Maintenance of Regulatory T cells
2013 StandoutNobel
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins
2019
Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling
2013
Physiology and Pathophysiology of Carnosine
2013 Standout
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans
2023 StandoutNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Mitophagy controls beige adipocyte maintenance through a Parkin-dependent and UCP1-independent mechanism
2018
Cross-Link Formation of the Cysteine 228−Tyrosine 272 Catalytic Cofactor of Galactose Oxidase Does Not Require Dioxygen
2008
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Treatment of nonalcoholic fatty liver disease: role of AMPK
2016
Copper Active Sites in Biology
2014 Standout
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
On Acetyl-CoA as a Gauge of Cellular Metabolic State
2011
Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise
2015
Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide
2006
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
2015
Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity
2016 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
SIRT6, a Mammalian Deacylase with Multitasking Abilities
2019
Xanthine oxidase and activated neutrophils cause oxidative damage to skeletal muscle after contractile claudication
2004
Mechanisms of Diabetic Complications
2013 Standout
The Mononuclear Molybdenum Enzymes
2014 Standout
Impact of Disordered Guest–Framework Interactions on the Crystallography of Metal–Organic Frameworks
2018 StandoutNobel
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Works of John E. Dominy being referenced
A Putative Fe 2+ -Bound Persulfenate Intermediate in Cysteine Dioxygenase
2008
Synthesis of Amino Acid Cofactor in Cysteine Dioxygenase Is Regulated by Substrate and Represents a Novel Post-translational Regulation of Activity
2008
In Vivo Regulation of Cysteine Dioxygenase via the Ubiquitin-26S Proteasome System
2006
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+
2011
Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin–26 S proteasome system in the living rat
2006
Mitochondrial Biogenesis through Activation of Nuclear Signaling Proteins
2013
In Vivo Measurement of the Acetylation State of Sirtuin Substrates as a Proxy for Sirtuin Activity
2013
Nutrient-Dependent Acetylation Controls Basic Regulatory Metabolic Switches and Cellular Reprogramming
2011
New Roles for Cysteine and Transsulfuration Enzymes: Production of H2S, A Neuromodulator and Smooth Muscle Relaxant
2004
Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase
2007
The sirtuin family’s role in aging and age-associated pathologies
2013
The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
2012
The cytoprotective role of taurine in exercise-induced muscle injury
2002
Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels
2008
Thiol dioxygenases: unique families of cupin proteins
2010
Oleic Acid Stimulates Complete Oxidation of Fatty Acids through Protein Kinase A-dependent Activation of SIRT1-PGC1α Complex
2013
Mammalian Cysteine Metabolism: New Insights into Regulation of Cysteine Metabolism
2006
Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5
2009
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation
2014
HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway
2008