Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Small GTP-Binding Proteins
1992
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Proteins regulating Ras and its relatives
1993 StandoutNature
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
The biochemical basis of the NADPH oxidase of phagocytes
1993
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product
1991 Nature
Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton
1998
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments
1990
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Phosphorylation and Desensitization of the Human β1-Adrenergic Receptor
1995 StandoutNobel
A region of the muscarinic-gated atrial K+ channel critical for activation by G protein βγ subunits
1994
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
2001
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits
1988 Nature
Crystal Structure of Human RhoA in a Dominantly Active Form Complexed with a GTP Analogue
1998
Rho and Rac Take Center Stage
2004 Standout
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
G protein multiplicity in eukaryotic signal transduction systems
1988
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
NF-κB: a key role in inflammatory diseases
2001 Standout
Inhibitor of nuclear factor ?B kinase ? is a key regulator of synovial inflammation
2001
rab5 controls early endosome fusion in vitro
1991
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1
1991
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
1999 StandoutNature
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
A novel role for RhoGDI as an inhibitor of GAP proteins.
1993
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Chromatographic resolution and immunologic identification of the alpha 40 and alpha 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain.
1988 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Bacterial toxins: cellular mechanisms of action
1984
Identification of Two GTP-Binding Proteins in the Chloroplast Protein Import Machinery
1994 StandoutScienceNobel
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
A GDP Dissociation Inhibitor That Serves as a GTPase Inhibitor for the Ras-Like Protein CDC42Hs
1992 Science
The human genome encodes at least three non‐allellic G proteins with αi‐type subunits
1987
Growth-regulated expression of rhoG, a new member of the ras homolog gene family.
1992
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels.
1988
Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum
1993 StandoutScienceNobel
Membrane receptors for bacterial toxins
1983
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Controlling mRNA lifespan
1988 StandoutNatureNobel
A Drosophila rotund transcript expressed during spermatogenesis and imaginal disc morphogenesis encodes a protein which is similar to human Rac GTPase-activating (racGAP) proteins.
1992
Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line
1990
Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation
1988 Science
The Cellular Functions of Small GTP-Binding Proteins
1990 Science
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase.
1993
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.
1994
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
The Effect of a T Cell-Specific NF-κB Inhibitor on In Vitro Cytokine Production and Collagen-Induced Arthritis
2000
Splice Variants of the α Subunit of the G Protein G s Activate Both Adenylyl Cyclase and Calcium Channels
1989 StandoutScienceNobel
Localized Rac Activation Dynamics Visualized in Living Cells
2000 Science
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Essential Role of T Cell NF-κB Activation in Collagen-Induced Arthritis
1999
Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase.
1992
Identification of a novel Rac1-interacting protein involved in membrane ruffling.
1996
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
Three-Dimensional Structure of Cholera Toxin Penetrating a Lipid Membrane
1988 StandoutScienceNobel
NF-κB Regulation by IκB Kinase-2 in Rheumatoid Arthritis Synoviocytes
2001
Essential role of T cell NF-kappa B activation in collagen-induced arthritis.
1999
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein.
1993
Inhibition of G protein-coupled receptor signaling by expression of cytoplasmic domains of the receptor.
1994 StandoutNobel
Works of John Didsbury being referenced
Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: Possible role in membrane localization
1990
Rac1, a low‐molecular‐mass GTP‐binding‐protein with high intrinsic GTPase activity and distinct biochemical properties
1992
Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins
1992
NF-κB activation provides the potential link between inflammation and hyperplasia in the arthritic joint
1998
Binding and Uptake of Diphtheria Toxin by Toxin-Resistant Chinese Hamster Ovary and Mouse Cells
1983
Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells.
1983
Human Gi protein α‐subunit: deduction of amino acid structure from a cloned cDNA
1987
Identification of the ral and rac1 Gene Products, Low Molecular Mass GTP-binding Proteins from Human Platelets
1989
Purification and characterization of an ADP-ribosyltransferase produced by Clostridium limosum.
1992
Molecular cloning of a new human G protein Evidence for two Giα‐like protein families
1987
Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5'-untranslated regions.
1986
Receptor class desensitization of leukocyte chemoattractant receptors.
1991
Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.
1993
Cross-desensitization of receptors for peptide chemoattractants. Characterization of a new form of leukocyte regulation.
1994
rac, a novel ras-related family of proteins that are botulinum toxin substrates
1989