Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Functional Cross-talk between β-Catenin and NFκB Signaling Pathways in Colonic Crypts of Mice in Response to Progastrin
2009
Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1
2012
The human fatty acid-binding protein family: Evolutionary divergences and functions
2011
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
1997 StandoutNature
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
2000 StandoutNature
The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates
1996 Standout
Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins
1994
Constitutive Activity in Melanocortin-4 Receptor
2014
Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors
2003
Fluorescent Labeling of Purified β2 Adrenergic Receptor
1995 StandoutNobel
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Sequence Alignment of the G-Protein Coupled Receptor Superfamily
1992
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
Central nervous system control of food intake and body weight
2006 StandoutNature
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Melanocortin Signalling Mechanisms
2010
Melanocortin-4 receptor-mediated inhibition of apoptosis in immortalized hypothalamic neurons via mitogen-activated protein kinase
2006
Structure and Conformational Changes in the C-terminal Domain of the β2-Adrenoceptor
2007 StandoutNobel
Pertussis Toxin-sensitive Signaling of Melanocortin-4 Receptors in Hypothalamic GT1-7 Cells Defines Agouti-related Protein as a Biased Agonist
2009
Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid
1993 StandoutNature
Identification of CC Chemokine Receptor 7 Residues Important for Receptor Activation
2004
The fatty acid transport function of fatty acid-binding proteins
2000
Evaluation of Melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
1996
Identification of an Allosteric Binding Site for Zn2+on the β2 Adrenergic Receptor
2002 StandoutNobel
A Novel Interaction between Adrenergic Receptors and the α-Subunit of Eukaryotic Initiation Factor 2B
1997 StandoutNobel
Effect of bile on the intestinal bile‐acid binding protein (I‐BABP) expression. In vitro and in vivo studies
1996
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
1997 Standout
Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man
1996
The melanocortin receptors and their accessory proteins
2013
Functional Selectivity of Melanocortin 4 Receptor Peptide and Nonpeptide Agonists: Evidence for Ligand-Specific Conformational States
2005
G Protein-coupled Receptors
1998 StandoutNobel
The Effect of pH on β2 Adrenoceptor Function
2000 StandoutNobel
Central nervous system control of food intake
2000 StandoutNature
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
1994 Nature
Physiological roles of the melanocortin MC3 receptor
2011
Mapping of the ACTH, MSH, and neural (MC3 and MC4) melanocortin receptors in the mouse and human
1994
Locating ligand-binding sites in 7tm receptors by protein engineering
1994
Immunity, Inflammation, and Cancer
2010 Standout
A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
1997 StandoutNobel
Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
2000
Synthesis and evaluation of bivalent ligands for binding to the human melanocortin-4 receptor
2014
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
2008
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans
2004
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
2000
Helicobacter pyloriInfection
2002 Standout
A novel family of genes encoding putative pheromone receptors in mammals
1995 StandoutNobel
Obesity and the Regulation of Energy Balance
2001 Standout
Exocrine Gland Dysfunction in MC5-R-Deficient Mice: Evidence for Coordinated Regulation of Exocrine Gland Function by Melanocortin Peptides
1997
Guidelines for the management of Helicobacter pylori infection
1998
Structure–activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors
2003
Molecular Cloning, Expression, and Characterization of a Human Intestinal 15‐kDa Protein
1995
Response of melanocortin–4 receptor–deficient mice to anorectic and orexigenic peptides
1999
Leptin and the regulation of body weight in mammals
1998 StandoutNature
The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R)
2005
Co-expression of Defective Luteinizing Hormone Receptor Fragments Partially Reconstitutes Ligand-induced Signal Generation
1997 StandoutNobel
Interleukin 1β and tumour necrosis factor α inhibit acid secretion in cultured rabbit parietal cells by multiple pathways
1998
Melanocortin-4 receptor–regulated energy homeostasis
2016
The genetic basis of colorectal cancer: Insights into critical pathways of tumorigenesis
2000
Activation of the Melanocortin-4 Receptor Mobilizes Intracellular Free Calcium in Immortalized Hypothalamic Neurons
2006
Confinement of Mobile Histamine in Coordination Nanochannels for Fast Proton Transfer
2011 StandoutNobel
Integration of NPY, AGRP, and Melanocortin Signals in the Hypothalamic Paraventricular Nucleus
1999
The Molecular Architecture of Odor and Pheromone Sensing in Mammals
2000 StandoutNobel
Molecular characterization of the melanin-concentrating-hormone receptor
1999 Nature
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
2003
Anti-inflammatory actions of the neuroimmunomodulator α-MSH
1997
Analogs of MTII, Lactam Derivatives of α-Melanotropin, Modified at the N-Terminus, and Their Selectivity at Human Melanocortin Receptors 3, 4, and 5
1999
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
2000 StandoutNature
A highly conserved tyrosine residue in G protein-coupled receptors is required for agonist-mediated beta 2-adrenergic receptor sequestration.
1994 StandoutNobel
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
1999
Ab initio study of tautomerism and of basicity center preference in histamine, from gas phase to solution—comparison with experimental data (gas phase, solution, solid state)
2003
Identification of Tetrapeptides from a Mixture Based Positional Scanning Library That Can Restore nM Full Agonist Function of the L106P, I69T, I102S, A219V, C271Y, and C271R Human Melanocortin-4 Polymorphic Receptors (hMC4Rs)
2014
Molecular cloning, tissue distribution, and expression of a 14-kDa bile acid-binding protein from rat ileal cytosol.
1994
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
The Effect of Mutations in the DRY Motif on the Constitutive Activity and Structural Instability of the Histamine H2 Receptor
2000
The Central Melanocortin System and Energy Homeostasis
1999
Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.
1994
Concentration and basicity of histamine rotamers
2002
Physiological and Anatomical Circuitry between Agouti-Related Protein and Leptin Signaling*
1999
Obesity-Induced Inflammation in White Adipose Tissue Is Attenuated by Loss of Melanocortin-3 Receptor Signaling
2007
The mouse ileal lipid-binding protein gene: a model for studying axial patterning during gut morphogenesis.
1994
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
2014 Standout
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
1996 StandoutNobel
The family of G‐protein‐coupled receptors
1995
Structural Mimicry in G Protein-Coupled Receptors: Implications of the High-Resolution Structure of Rhodopsin for Structure-Function Analysis of Rhodopsin-Like Receptors
2001
Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans
2004
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.
1996
Melanocortin Antagonists Define Two Distinct Pathways of Cardiovascular Control by α- and γ-Melanocyte-Stimulating Hormones
1996
A meta‐analysis of short versus long therapy with a proton pump inhibitor, clarithromycin and either metronidazole or amoxycillin for treating Helicobacter pylori infection
2000
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
2010
Melanocortin receptors: their functions and regulation by physiological agonists and antagonists
2001
Molecular Properties and Regulation of G-Protein-Coupled Receptors
1994
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Enterochromaffin-Like Cells, a Cellular Source of Uroguanylin in Rat Stomach*
1999
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
The Binding Site of Aminergic G Protein–Coupled Receptors: The Transmembrane Segments and Second Extracellular Loop
2002
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Different Effects of Gsα Splice Variants on β2-Adrenoreceptor-mediated Signaling
1998 StandoutNobel
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Gut hormone PYY3-36 physiologically inhibits food intake
2002 StandoutNature
Identification of a Nuclear Receptor for Bile Acids
1999 StandoutScience
A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors
2000
Works of John DelValle being referenced
The Stomach as an Endocrine Organ
1997
Splanchnic and Cerebral Vasodilatory Effects of Calcitonin Gene-related Peptide I in Humans
1991
Epidermal growth factor inhibits carbachol-stimulated canine parietal cell function via protein kinase C
1996
Post-translational processing of gastrin in neoplastic human colonic tissues
1992
Effect of transforming growth factor alpha and interleukin 8 on somatostatin release from canine fundic D cells
1997
Molecular cloning of the human histamine H2 receptor
1991
Molecular basis for the interaction of histamine with the histamine H2 receptor.
1992
The Gut as an Endocrine Organ
1990
Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor.
1994
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor
1993
Lansoprazole and ranitidine affect the accuracy of the 14C-urea breath test by a pH-dependent mechanism.
1997
Molecular cloning of a novel melanocortin receptor.
1993
Gastrotropin: not an enterooxyntin but a member of a family of cytoplasmic hydrophobic ligand binding proteins
1989
Histamine H2 receptor activates adenylate cyclase and PLC via separate GTP-dependent pathways
1996