Citation Impact
Citing Papers
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences
2006 Standout
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex
2009 StandoutNobel
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
2019 StandoutNobel
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
2020
Covalent inhibitors of glycosidases and their applications in biochemistry and biology
2008
Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA
1998
Recent progress in the biology, chemistry and structural biology of DNA glycosylases
2001
Phage P22 tailspike protein: crystal structure of the head-binding domain at 2.3 Å, fully refined structure of the endorhamnosidase at 1.56 Å resolution, and the molecular basis of O-antigen recognition and cleavage
1997 Nobel
Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation
2012
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
2013 Standout
Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors
2015
Assignment of Sweet Almond β-Glucosidase as a Family 1 Glycosidase and Identification of Its Active Site Nucleophile
1997
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
The genetics of ageing
2010 StandoutNature
Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets
2011
Computational Enzyme Design
2013 StandoutNobel
Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease
1996
The crystal structure of rhamnogalacturonase A from Aspergillus aculeatus: a right-handed parallel β helix
1997
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
β-Galactosidase-instructed formation of molecular nanofibers and a hydrogel
2011
Trapping Covalent Intermediates on β-Glycosidases
2002
The crystal structures of Sinapis alba myrosinase and a covalent glycosyl–enzyme intermediate provide insights into the substrate recognition and active-site machinery of an S-glycosidase
1997
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Resveratrol is Not a Direct Activator of SIRT1 Enzyme Activity
2009
The carbohydrate-active enzymes database (CAZy) in 2013
2013 Standout
The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum
1996
Impaired negative feedback suppression of bile acid synthesis in mice lacking βKlotho
2005
Functional metagenomics identifies an exosialidase with an inverting catalytic mechanism that defines a new glycoside hydrolase family (GH156)
2018
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Structural and sequence-based classification of glycoside hydrolases
1997 Standout
Cloning and characterization of Thermotoga maritima β-glucuronidase
2005
Crystal structure of the catalytic domain of a bacterial cellulase belonging to family 5
1995
Crystallographic observation of a covalent catalytic intermediate in a β-glycosidase
1996
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Structures and mechanisms of glycosyl hydrolases
1995 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
The Polar Hydrophobicity of Fluorinated Compounds
2004
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Approaches to labeling and identification of active site residues in glycosidases
1995
Klotho converts canonical FGF receptor into a specific receptor for FGF23
2006 StandoutNature
Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid
2008
Reaction Kinetics, Molecular Action, and Mechanisms of Cellulolytic Proteins
1999
Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway
2010
The identification of the catalytic nucleophiles of two β-galactosidases from glycoside hydrolase family 35
2001
Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
2004
The Hydrogen Bond in the Solid State
2002 Standout
Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry
2012 StandoutNobel
Cellulose: Fascinating Biopolymer and Sustainable Raw Material
2005 Standout
A New Sialidase Mechanism
2009
The Acid/Base Catalyst in the Exoglucanase/Xylanase from Cellulomonas fimi Is Glutamic Acid 127: Evidence from Detailed Kinetic Studies of Mutants
1994
Protease inhibitors targeting coronavirus and filovirus entry
2015
Engineering the third wave of biocatalysis
2012 StandoutNature
Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure
2002
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Snapshots along an Enzymatic Reaction Coordinate: Analysis of a Retaining β-Glycoside Hydrolase,
1998
3d Transition Metals for C–H Activation
2018 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Targeted Covalent Inhibitors for Drug Design
2016
Stability studies of hydrazide and hydroxylamine-based glycoconjugates in aqueous solution
2008
A study of the reactivity of S(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions
2017
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Fundamental Challenges in Mechanistic Enzymology: Progress toward Understanding the Rate Enhancements of Enzymes
2013
Design and Synthesis of Activity Probes for Glycosidases
2002
X-ray structure of an anti-fungal chitosanase from streptomyces N174
1996
Synthesis of Glycopolymers for Microarray Applications via Ligation of Reducing Sugars to a Poly(acryloyl hydrazide) Scaffold
2010 StandoutNobel
Crystal Structure of Thermostable Family 5 Endocellulase E1 from Acidothermus cellulolyticus in Complex with Cellotetraose,
1996
Chemical Glycobiology
2001 StandoutScienceNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Targeted metabolic labeling of yeast N-glycans with unnatural sugars
2010 StandoutNobel
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Structure of a two-domain chitotriosidase from Serratia marcescens at 1.9-Å resolution
2000
Functional π-Gelators and Their Applications
2014 Standout
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Nucleophilic Trifluoromethylation Reactions of Organic Compounds with (Trifluoromethyl)trimethylsilane
2000
Recent applications of click chemistry in drug discovery
2019
Structure of the Aspergillus oryzae α-Amylase Complexed with the Inhibitor Acarbose at 2.0 Å Resolution,
1997
DAST-Mediated Regioselective Anomeric Group Migration in Saccharides
2009
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Access to Oxetane-Containing psico-Nucleosides from 2-Methyleneoxetanes: A Role for Neighboring Group Participation?
2011
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Synthesis of 4,4-difluoroglycosides using ring-closing metathesis
2004
Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
2012
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
How good is fluorine as a hydrogen bond acceptor?
1996
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the α-amylase family
1999
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Stereoselective C-Glycosylation Reactions of Ribose Derivatives: Electronic Effects of Five-Membered Ring Oxocarbenium Ions
2005
Synthesis of Transportation Fuels from Biomass: Chemistry, Catalysts, and Engineering
2006 Standout
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Fragmentation of Carbohydrate Anomeric Alkoxyl Radicals: A New Synthesis of 1,1-Difluoro-1-iodo Alditols
2003
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: Mimicry of carbohydrate substrate
2002 StandoutNobel
Trypanosoma cruzi Trans-sialidase Operates through a Covalent Sialyl−Enzyme Intermediate: Tyrosine Is the Catalytic Nucleophile
2003
Trichodiene Synthase: Synthesis and Inhibition Kinetics of 12‐Fluoro‐farnesylphosphonophosphate for Sesquiterpene Cyclases
2006
In vitro synthesis of cellulose and related polysaccharides
2001
Filamentous Phage Display in the New Millennium
2005
Substrate Specificity of the Glycosyl Donor for Oligosaccharyl Transferase
2001
Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors: Mannostatins, Trehazolin, Allosamidins, and Their Analogues
1999
Application of Designed Enzymes in Organic Synthesis
2011
Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity
2005
Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors
2010
Works of John D. McCarter being referenced
Discovery of Acetyl-Coenzyme A Carboxylase 2 Inhibitors: Comparison of a Fluorescence Intensity-Based Phosphate Assay and a Fluorescence Polarization-Based ADP Assay for High-Throughput Screening
2007
Mechanisms of enzymatic glycoside hydrolysis
1994
Syntheses of 2-deoxy-2-fluoro mono- and oligo-saccharide glycosides from glycals and evaluation as glycosidase inhibitors
1993
Identification of Glu-268 as the Catalytic Nucleophile of Human Lysosomal β-Galactosidase Precursor by Mass Spectrometry
1997
Unequivocal Identification of Asp-214 as the Catalytic Nucleophile of Saccharomyces cerevisiae α-Glucosidase Using 5-Fluoro Glycosyl Fluorides
1996
Keto-1,3,4-oxadiazoles as cathepsin K inhibitors
2006
Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors
2011
The imidazo[1,2-a]pyridine ring system as a scaffold for potent dual phosphoinositide-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitors
2015
High-throughput assays for sirtuin enzymes: A microfluidic mobility shift assay and a bioluminescence assay
2008
5-Fluoro Glycosides: A New Class of Mechanism-Based Inhibitors of Both α- and β-Glucosidases
1996
The Role of Sugar Substituents in Glycoside Hydrolysis
2000
Substrate Specificity of the Escherichia coli Outer Membrane Protease OmpT
2004
Systematic Study of the Glutathione (GSH) Reactivity ofN-Arylacrylamides: 1. Effects of Aryl Substitution
2015
Syntheses, radiolabelling, and kinetic evaluation of 2-deoxy-2-fluoro-2-iodo-d-hexoses for medical imaging
1995
In vivo inhibition of β-glucosidase and β-mannosidase activity in rats by 2-deoxy-2-fluoro-β-glycosyl fluorides and recovery of activity in vivo and in vitro
1994
A Structural View of the Action ofEscherichia coli(lacZ) β-Galactosidase,
2001
Design and Synthesis of 2‘-Deoxy-2‘-Fluorodisaccharides as Mechanism-Based Glycosidase Inhibitors That Exploit Aglycon Specificity
1997
Synthesis and Testing of 2-Deoxy-2,2-Dihaloglycosides as Mechanism-Based Inhibitors of α-Glycosidases
2008
A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation
2017
Identification of Glu340 as the active-site nucleophile in human glucocerebrosidase by use of electrospray tandem mass spectrometry
1994
Binding energy and catalysis. Fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase
1992