Standout Papers
Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
The Cell Biology of Phagocytosis
2011
Mechanisms of nitric oxide-related antimicrobial activity
1997
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase
1999
Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression
2006 Standout
Central Role of Transcription Factor NF-IL6 for Cytokine and Iron-Mediated Regulation of Murine Inducible Nitric Oxide Synthase Expression
1999
Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells
1999
In silico prediction of protein-protein interactions in human macrophages
2014 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Nitric Oxide Production and Nitric Oxide Synthase Type 2 Expression by Human Mononuclear Phagocytes: A Review
1998
The Ectoenzyme γ-Glutamyl Transpeptidase Regulates Antiproliferative Effects of S-Nitrosoglutathione on Human T and B Lymphocytes
1999
A Role for Nitric Oxide-Mediated Peroxynitrite Formation in a Model of Endotoxin-Induced Shock
2006
Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity
2000
The chemistry of DNA damage from nitric oxide and peroxynitrite
1999
Mammary tumor latency is increased in mice lacking the inducible nitric oxide synthase
2003
Inflammation and cancer
2002 StandoutNature
Immune evasion by Mycobacterium tuberculosis: living with the enemy
2003
Nitrotyrosine generation via inducible nitric oxide synthase in vascular wall in focal ischemia-reperfusion
2000
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.
1997 Standout
Nitrosative Stress: Activation of the Transcription Factor OxyR
1996
Nitric Oxide Synthase and Postischemic Liver Injury
2000
Effect of uric acid on liver injury during hemorrhagic shock☆
2000
Physiological and pathophysiological roles of nitric oxide in the central nervous system
1996
Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
2006
Nitric oxide in autoimmune disease: cytotoxic or regulatory mediator?
1998
NO Inhibitions: Antimicrobial Properties of Nitric Oxide
1995
Inducible nitric oxide synthase: what difference does it make?
1997
Tumor-Associated Macrophages in Breast Cancer
2002
Molecular mechanisms in the early phase of hemorrhagic shock
2001
Expression and Regulation of Endothelial Nitric Oxide Synthase
1997
GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury
2003
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
1994
An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells
2003
Inducible nitric oxide synthase expression in human cerebral infarcts
1999
Hemoglobin protects from streptococcal cell wall-induced arthritis
1999
IgA Adaptation to the Presence of Commensal Bacteria in the Intestine
2006
Essential Roles of S-Nitrosothiols in Vascular Homeostasis and Endotoxic Shock
2004
A Critical Role for Inducible Nitric Oxide Synthase in Host Survival Following Coxsackievirus B4 Infection
2001
Activation and regulation of the inflammasomes
2013 Standout
Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models
2003
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Development of Lyme Arthritis in Mice Deficient in Inducible Nitric Oxide Synthase
1999
Mitogen-activated protein kinase pathways
1997 Standout
Listeriosis in p47phox−/− and TRp55−/− Mice: Protection Despite Absence of ROI and Susceptibility Despite Presence of RNI
1997
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
2015
Regulatory Interactions between Iron and Nitric Oxide Metabolism for Immune Defense againstPlasmodium falciparumInfection
2001
Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras
1995
IFN-γ-Dependent Nitric Oxide Production Is Not Linked to Resistance in Experimental African Trypanosomiasis
1999
Nitrosylation
2001
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
2014 Nature
A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion
2002
The Hallmarks of Cancer
2000 Standout
Oxidative stress in septic shock and disseminated intravascular coagulation
2002
Unraveling peroxynitrite formation in biological systems
2001
Protein Nitration in Cardiovascular Diseases
2002
Nonresolving Inflammation
2010 Standout
Paracrine and autocrine effects of nitric oxide on myocardial function
2000
Biology of nitric oxide signaling
2000
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Inhibition of inducible nitric oxide synthase improves graft function and reduces tubulointerstitial injury in renal allograft rejection
2000
Requirement for Lymphoid Tissue-Inducer Cells in Isolated Follicle Formation and T Cell-Independent Immunoglobulin A Generation in the Gut
2008
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
IFN-γ and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation
2000
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
2003
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides.
1995
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Severe Inflammation and Reduced Bacteria Load in MurineHelicobacterInfection Caused by Lack of Phagocyte Oxidase Activity
2003
An inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune myocarditis in Lewis rats
1998
Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-like Activity via Two Distinct Mechanisms
1997
Resistance to endotoxic shock as a consequence of defective NF-kappa B activation in poly (ADP-ribose) polymerase-1 deficient mice
1999
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Interferon-γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs
2002
Cas9 as a versatile tool for engineering biology
2013
Neurodegenerative disorders: the role of peroxynitrite
1999
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
2013 Standout
Fas–FasL interaction modulates nitric oxide production in Trypanosoma cruzi‐infected mice
2001
Nitric oxide and the regulation of gene expression
2001
Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense
2017
p47 GTPases: regulators of immunity to intracellular pathogens
2004
Genetic, Biochemical, and Clinical Features of Chronic Granulomatous Disease
2000
Nitric oxide inhibits viral replication in murine myocarditis.
1996
Nitric Oxide as a Regulator of Embryonic Development
1998
Interferon signalling network in innate defence
2006
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
The role of uric acid in protection against peroxynitrite-mediated pathology
2001
Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis
2002
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: Structures and mechanisms of product formation
2005
Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation
1994
Nitric oxide (NO): an effector of apoptosis
1999
Tumour-educated macrophages promote tumour progression and metastasis
2004 Standout
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Protective role of the cytokine‐inducible isoform of nitric oxide synthase induction and nitrosative stress in experimental autoimmune encephalomyelitis of the DA rat
2003
Effects of nitric oxide on the induction and differentiation of Th1 cells
1999
NOS-2 Mediates the Protective Anti-Inflammatory and Antifibrotic Effects of the Th1-Inducing Adjuvant, IL-12, in a Th2 Model of Granulomatous Disease
2000
The macrophage: Past, present and future
2007
Dependence of Liver Injury After Hemorrhage/Resuscitation in Mice on NADPH Oxidase-Derived Superoxide
2003
Partial Impairment of Cytokine Responses in Tyk2-Deficient Mice
2000
An Inducible Nitric-oxide Synthase (NOS)-associated Protein Inhibits NOS Dimerization and Activity
1999
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
TNF/iNOS-Producing Dendritic Cells Mediate Innate Immune Defense against Bacterial Infection
2003
Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
2004 Standout
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
2002
Umbilical Arterial S-nitrosothiols in Stressed Newborns: Role in Perinatal Circulatory Transition
1998 StandoutNobel
Differential Sensitivity of the Tyrosyl Radical of Mouse Ribonucleotide Reductase to Nitric Oxide and Peroxynitrite
1998
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
2002 Standout
NO as a signaling molecule: effects on kinases
2001
The TNF and TNF Receptor Superfamilies
2001 Standout
Effect of hypoxia on proximal tubules isolated from nitric oxide synthase knockout mice
1998
Cancer-related inflammation
2008 StandoutNature
Sustained Nitric Oxide Production in Macrophages Requires the Arginine Transporter CAT2
2001
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β
2012
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Is nitric oxide overproduction the target of choice for the management of septic shock?
2001
Exploring the full spectrum of macrophage activation
2008 Standout
Complex Contribution of the 3′-Untranslated Region to the Expressional Regulation of the Human Inducible Nitric-oxide Synthase Gene
2000
Nitric oxide function in the skin
2004
Mammalian nitric oxide synthases
1999
Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment
2000 StandoutNobel
The roles of IFNγ in protection against tumor development and cancer immunoediting
2002
Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malaria
2000
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Radical causes of cancer
2003
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
2011 StandoutNobel
Enhanced Post-Ischemic Liver Injury in iNOS-Deficient Mice: A Cautionary Note
2001
Macrophage activation and polarization
2007 Standout
Macrophages Inhibit Salmonella Typhimurium Replication through MEK/ERK Kinase and Phagocyte NADPH Oxidase Activities
2002
Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species soecificity
1995
Involvement of NO in contact hypersensitivity
1998
Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats
2004
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
2015
Nitric Oxide Inhibits Hepatitis B Virus Replication in the Livers of Transgenic Mice
2000
Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): Potential role of cyclin D1
2001
Peptide methionine sulfoxide reductase fromEscherichia coliandMycobacterium tuberculosisprotects bacteria against oxidative damage from reactive nitrogen intermediates
2001
Effect of Nitric Oxide Donors on Oxygen-Dependent Cytotoxic Responses Mediated by Neutrophils
1999
Expression of NADPH Oxidase-Dependent Resistance to Listeriosis in Mice Occurs during the First 6 to 12 Hours of Liver Infection
2002
Effects of cytokines on mycobacterial phagosome maturation
1998
Human NK Cells Express Endothelial Nitric Oxide Synthase, and Nitric Oxide Protects Them from Activation-Induced Cell Death by Regulating Expression of TNF-α
1999
A Proinflammatory Cytokine Inhibits P53 Tumor Suppressor Activity
1999
Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis
2001
Inducible nitric-oxide synthase plays a minimal role in lymphocytic choriomeningitis virus-induced, T cell-mediated protective immunity and immunopathology
1999
Immunology of Tuberculosis
2001 Standout
Induction of Inducible Nitric Oxide Synthase-NO· by Lipoarabinomannan ofMycobacterium tuberculosisIs Mediated by MEK1-ERK, MKK7-JNK, and NF-κB Signaling Pathways
2001
Neuronal Nitric Oxide Synthase Activation and Peroxynitrite Formation in Ischemic Stroke Linked to Neural Damage
1999
Nitric Oxide Suppresses Human T Lymphocyte Proliferation Through IFN-γ-Dependent and IFN-γ-Independent Induction of Apoptosis
1999
Role of Nitric Oxide Synthase Type 2 in Acute Infection with Murine Cytomegalovirus
2001
Differential Expression of Nitric Oxide Synthases in Bacterial Meningitis: Role of the Inducible Isoform for Blood‐Brain Barrier Breakdown
2001
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
CELL BIOLOGY OFMYCOBACTERIUM TUBERCULOSISPHAGOSOME
2004
The Three Es of Cancer Immunoediting
2004 Standout
Extensive peroxynitrite activity during progressive stages of central nervous system inflammation
1997
Antimicrobial Actions of the Nadph Phagocyte Oxidase and Inducible Nitric Oxide Synthase in Experimental Salmonellosis. II. Effects on Microbial Proliferation and Host Survival in Vivo
2000
Chronic granulomatous disease
2000
The ectoenzyme gamma-glutamyl transpeptidase regulates antiproliferative effects of S-nitrosoglutathione on human T and B lymphocytes.
1999
Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control ofMycobacterium tuberculosisin the Murine Lung
2000
The many faces of macrophage activation
2003
Rapidly Fatal Leishmaniasis in Resistant C57BL/6 Mice Lacking TNF
2001
Fate ofMycobacterium tuberculosiswithin Murine Dendritic Cells
2001
Clinical and Serologic Manifestations of Autoimmune Disease in MRL-lpr/lpr Mice Lacking Nitric Oxide Synthase Type 2
1997
Interleukin-2–Activated Rat Natural Killer Cells Express Inducible Nitric Oxide Synthase That Contributes to Cytotoxic Function and Interferon-γ Production
1999
Nitric oxide and the immune response
2001 Standout
M-1/M-2 Macrophages and the Th1/Th2 Paradigm
2000 Standout
Viral mutation accelerated by nitric oxide production during infection in vivo
2000
Depletion of Cd4+ T Cells Causes Reactivation of Murine Persistent Tuberculosis despite Continued Expression of Interferon γ and Nitric Oxide Synthase 2
2000
Reactive oxygen species in cell signaling
2000 Standout
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Adjuvant Immunotherapy Is Dependent on Inducible Nitric Oxide Synthase
2001
Role of Oxidants in Ischemic Brain Damage
1996
Therapeutic Administration of a Selective Inhibitor of Nitric Oxide Synthase Does Not Ameliorate the Chronic Inflammation and Tissue Damage Associated with Adjuvant-Induced Arthritis in Rats
1998
Impaired Production of Proinflammatory Cytokines and Host Resistance to Acute Infection withTrypanosoma cruziin Mice Lacking Functional Myeloid Differentiation Factor 88
2004
Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells
2000
Neural Route of CerebralListeria monocytogenesMurine Infection: Role of Immune Response Mechanisms in Controling Bacterial Neuroinvasion
2001
Inducible Nitric Oxide Synthase Protection Against Coxsackievirus Pancreatitis
1999
Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis.
1996
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
1994 Standout
Requirement for Type 2 NO Synthase for IL-12 Signaling in Innate Immunity
1999 Science
Blockade of B7-H1 on Macrophages Suppresses CD4+ T Cell Proliferation by Augmenting IFN-γ-Induced Nitric Oxide Production
2005
Inhibition of viral replication by nitric oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites.
1995
Salmonella entericaSerovar Typhimurium-Dependent Regulation of Inducible Nitric Oxide Synthase Expression in Macrophages by Invasins SipB, SipC, and SipD and Effector SopE2
2000
Cytokine-Mediated Apoptosis in Cardiac Myocytes
1999
Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase
2001
Regulation of Human Immunodeficiency Virus Type 1 Replication in Human T Lymphocytes by Nitric Oxide
2001
Impaired liver regeneration in inducible nitric oxide synthasedeficient mice
1998
Pattern of Macrophage Activation in Yersinia‐Resistant and Yersinia‐Susceptible Strains of Mice
2007
2000
Cutting Edge: Bacterial DNA and LPS Act in Synergy in Inducing Nitric Oxide Production in RAW 264.7 Macrophages
1999
Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite
2001
Biphasic Regulation of NF-κB Activity Underlies the Pro- and Anti-Inflammatory Actions of Nitric Oxide
2001
Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.
1995
Regulation of biosynthesis of nitric oxide.
1994
Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death
2002
Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages
1994 Science
The mosquitoAnopheles stephensilimits malaria parasite development with inducible synthesis of nitric oxide
1998
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Selective Inhibition of Inducible Nitric Oxide Synthase Exacerbates Erosive Joint Disease
2001
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
The Inhibitory Action of Sodium Arsenite on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 267.4 Macrophage Cells: A Role of Raf-1 in Lipopolysaccharide Signaling
2001
Macrophage Microbicidal Mechanisms In Vivo: Reactive Nitrogen versus Oxygen Intermediates in the Killing of Intracellular Visceral Leishmania donovani
1999
Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice
1999
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
2014
Genetic requirements for mycobacterial survival during infection
2003 Standout
Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice
2000
Antimicrobial Actions of the Nadph Phagocyte Oxidase and Inducible Nitric Oxide Synthase in Experimental Salmonellosis. I. Effects on Microbial Killing by Activated Peritoneal Macrophages in Vitro
2000
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals.
1996
Interleukin 12 Protects from a T Helper Type 1–mediated Autoimmune Disease, Experimental Autoimmune Uveitis, through a Mechanism Involving Interferon γ, Nitric Oxide, and Apoptosis
1999
Coronavirus-Induced Demyelination Occurs in the Absence of Inducible Nitric Oxide Synthase
2000
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
2000
Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes
2016
Granulocytic Ehrlichiosis in Mice Deficient in Phagocyte Oxidase or Inducible Nitric Oxide Synthase
2000
Nitric Oxide Mediation of Active Immunosuppression Associated With Graft-Versus-Host Reaction
1999
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells
2003
Regulation of Murine Intestinal Inflammation by Reactive Metabolites of Oxygen and Nitrogen
2001
Tumor-induced immune dysfunction: the macrophage connection
1998
Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene
1997
Induction of Intracellular Arginase Activity Does not Diminish the Capacity of Macrophages to Produce Nitric Oxide in vitro
1999
Activation of nitric oxide synthase gene for inhibition of cancer metastasis
1996
Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte–endothelium interactions in endotoxemia
1997
Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors
2001 Science
Recognition of Bacteria by Inflammasomes
2012
Nitric Oxide Synthase-2 and Expression of Perforin in Uterine NK Cells
2000
Disruption of Inducible Nitric Oxide Synthase Improves β-Adrenergic Inotropic Responsiveness but Not the Survival of Mice With Cytokine-Induced Cardiomyopathy
2002
Role of Inducible Nitric Oxide Synthase in Resistance toMycobacterium lepraein Mice
2000
Suppression of arthritis by an inhibitor of nitric oxide synthase.
1993
Human NK cells express endothelial nitric oxide synthase, and nitric oxide protects them from activation-induced cell death by regulating expression of TNF-alpha.
1999
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 Standout
Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis.
1999
Enhancement of T Cell Receptor Signaling by a Mild Oxidative Shift in the Intracellular Thiol Pool
2000
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase.
1996
The Multiplex Function of Nitric Oxide in (Auto)immunity
1998
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Arginine metabolism: nitric oxide and beyond
1998 Standout
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Myeloperoxidase: friend and foe
2005 Standout
The phagocytes: neutrophils and monocytes
2008
Cytokine Activation Leads to Acidification and Increases Maturation of Mycobacterium avium-Containing Phagosomes in Murine Macrophages
1998
Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice
2000
Works of John D. MacMicking being referenced
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Interferon-inducible effector mechanisms in cell-autonomous immunity
2012
Type 1 Interferon (IFNα/β) and Type 2 Nitric Oxide Synthase Regulate the Innate Immune Response to a Protozoan Parasite
1998
IFN-Inducible GTPases in Host Cell Defense
2012
Phenotype of Mice and Macrophages Deficient in Both Phagocyte Oxidase and Inducible Nitric Oxide Synthase
1999
LETHALITY OF ENDOTOXIN IN MICE GENETICALLY DEFICIENT IN THE RESPIRATORY BURST OXIDASE, INDUCIBLE NITRIC OXIDE SYNTHASE, OR BOTH
1999
Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria
2009
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
1995
Immune control of phagosomal bacteria by p47 GTPases
2005
Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii
2013
Identification of nitric oxide synthase as a protective locus against tuberculosis
1997
GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals
2012 Science
Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance
2000
Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase
1993 Science
Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells.
1992
NITRIC OXIDE AND MACROPHAGE FUNCTION
1997 Standout
A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial Infection
2011 Science
Rapid Interferon γ–dependent Clearance of Influenza A Virus and Protection from Consolidating Pneumonitis in Nitric Oxide Synthase 2–deficient Mice
1998
Identification ofNitric Oxide Synthase 2as an Innate Resistance Locus against Ectromelia Virus Infection
1998
Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock
1998
Cellular Self-Defense: How Cell-Autonomous Immunity Protects Against Pathogens
2013 Science