Citation Impact
Citing Papers
Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia
2013 StandoutNobel
Visualizing extravasation dynamics of metastatic tumor cells
2010
Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion
2008
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
Cell entry mechanisms of SARS-CoV-2
2020 Standout
Specific Cross-talk between Epidermal Growth Factor Receptor and Integrin αvβ5 Promotes Carcinoma Cell Invasion and Metastasis
2009
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Requirement of TCF7L2 for TGF-β-dependent Transcriptional Activation of the TMEPAI Gene
2010
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes
2015
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
2017 StandoutNobel
Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead
2007
Hepsin promotes prostate cancer progression and metastasis
2004
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis
2009
Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
2010
Novel insights into proteolytic cleavage of influenza virus hemagglutinin
2010
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling
2013
A Novel Proteomic Approach for Specific Identification of Tyrosine Kinase Substrates Using [13C]Tyrosine
2004
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Cancer Metastasis: Building a Framework
2006 Standout
TGFβ signalling in context
2012 Standout
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
2009
Potentiation of neuroblastoma metastasis by loss of caspase-8
2006 Nature
Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome
2010
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
2020 StandoutNobel
Unleashing the therapeutic potential of human kallikrein-related serine proteases
2015
Emerging roles of proteases in tumour suppression
2007
A Proteolytic Cascade of Kallikreins in the Stratum Corneum
2005
Cancer stem cells revisited
2017 Standout
The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
2009 StandoutNobel
Genetic upregulation of matriptase‐2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation
2008
Human and mouse proteases: a comparative genomic approach
2003
The Structure of the Extracellular Region of Human Hepsin Reveals a Serine Protease Domain and a Novel Scavenger Receptor Cysteine-Rich (SRCR) Domain
2003
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Autocatalytic Cleavage of the EMR2 Receptor Occurs at a Conserved G Protein-coupled Receptor Proteolytic Site Motif
2004
Probing the substrate specificities of matriptase, matriptase‐2, hepsin and DESC1 with internally quenched fluorescent peptides
2009
Kallikrein-Related Peptidase 14 Acts on Proteinase-Activated Receptor 2 to Induce Signaling Pathway in Colon Cancer Cells
2011
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
2006
The development of allergic inflammation
2008 StandoutNature
Revealing the human mucinome
2022 StandoutNobel
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial–mesenchymal transition
2007
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
2007 Standout
Iron refractory iron deficiency anemia
2013
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum
2006
Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase
2001
Emerging Biological Principles of Metastasis
2017 Standout
Structural Basis of the Zinc Inhibition of Human Tissue Kallikrein 5
2007 Nobel
The Impact of Cardiac Natriuretic Peptide Determination on the Diagnosis and Management of Heart Failure
2001
Targeting proteinase-activated receptors: therapeutic potential and challenges
2012
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Circulating mutant DNA to assess tumor dynamics
2008 Standout
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
EMT: 2016
2016 Standout
Targeting metastasis
2016
Intraoperative detection and removal of microscopic residual sarcoma using wide‐field imaging
2012 StandoutNobel
Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7
2011
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Protease–proteoglycan complexes of mouse and human mast cells and importance of their β‐tryptase–heparin complexes in inflammation and innate immunity
2007
The cell surface mucin MUC1 limits the severity of influenza A virus infection
2017
Iron-Refractory Iron Deficiency Anemia (IRIDA)
2014
The multifunctional or moonlighting protein CD26/DPPIV
2003
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
2007
Matrix metalloproteinases and tumor metastasis
2006 Standout
Rapid Measurement of B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure
2002 Standout
Mass Spectrometric Analysis of Agonist Effects on Posttranslational Modifications of the β-2 Adrenoceptor in Mammalian Cells
2005 StandoutNobel
Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers
2005
Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium
2006
Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency
2008
Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors
2016
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling
2005 Standout
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
2010 Nobel
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
2013 StandoutNobel
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism
2013
Inhibition of Lymphogenous Metastasis Using Adeno-Associated Virus-Mediated Gene Transfer of a Soluble VEGFR-3 Decoy Receptor
2005
Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion Competence
2012
Serial Assessment of Human Tumor Burdens in Mice by the Analysis of Circulating DNA
2007
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Phenotypic Analysis of Mice Lacking the Tmprss2-Encoded Protease
2006
Esophageal Cancer: Associated Factors with Special Reference to the Kashmir Valley
2012
Modulation of CD11b/CD18 Adhesive Activity by Its Extracellular, Membrane-Proximal Regions
2003
A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry
2010
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases
2005
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
2018
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
2008
Iron-Deficiency Anemia
2015 Standout
Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
2008
Protease degradomics: A new challenge for proteomics
2002
Matriptase-2 Inhibits Breast Tumor Growth and Invasion and Correlates with Favorable Prognosis for Breast Cancer Patients
2007
Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3
2003
Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis
2010
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition
2015
Global cancer statistics, 2012
2015 Standout
A Disaccharide-Based Inhibitor of Glycosylation Attenuates Metastatic Tumor Cell Dissemination
2006
Recent Advances in Glycoproteomic Analysis by Mass Spectrometry
2019
Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein
2010
Works of John D. Hooper being referenced
Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis
2001
Type II Transmembrane Serine Proteases
2001
Identification and Characterization of KLK14, a Novel Kallikrein Serine Protease Gene Located on Human Chromosome 19q13.4 and Expressed in Prostate and Skeletal Muscle
2001
Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer
2003
Tissue-specific Expression Patterns and Fine Mapping of the Human Kallikrein (KLK) Locus on Proximal 19q13.4
2000
Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors
2001
The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2
2011
Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
2009
Structure, function and pathophysiology of protease activated receptors
2011
Localization of the mosaic transmembrane serine protease corin to heart myocytes
2000
Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells
2011
Kallikrein-related Peptidase 4 (KLK4) Initiates Intracellular Signaling via Protease-activated Receptors (PARs)
2008
The Expanded Human Kallikrein (KLK) Gene Family: Genomic Organisation, Tissue-Specific Expression and Potential Functions
2001
MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target
2016
TTYH2, a Human Homologue of the Drosophila melanogaster Gene tweety, Is Located on 17q24 and Upregulated in Renal Cell Carcinoma
2001
Proteomic analysis of exosomes reveals an association between cell invasiveness and exosomal bioactivity on endothelial and mesenchymal cell migrationin vitro
2018
A quantitative analysis of rate-limiting steps in the metastatic cascade using human-specific real-time polymerase chain reaction.
2002
Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues
2003
Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors.
1999
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs)
2008