Citation Impact
Citing Papers
A Genomic View of the Human- Bacteroides thetaiotaomicron Symbiosis
2003 Science
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
Origins of Specificity in Protein-DNA Recognition
2010
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Novel Organic Hydroperoxide-Sensing and Responding Mechanisms for OhrR, a Major Bacterial Sensor and Regulator of Organic Hydroperoxide Stress
2006
Identification of direct residue contacts in protein–protein interaction by message passing
2008
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era
2013 StandoutNobel
Alkyl Hydroperoxide Reductase Is the Primary Scavenger of Endogenous Hydrogen Peroxide in Escherichia coli
2001
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Iron‐sulphur clusters and the problem with oxygen
2006
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE
1991 Nature
Structural Basis of Transcription
2004 StandoutNobel
Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE
1991 Nature
Novel Mycobacterium tuberculosis anti‐σ factor antagonists control σF activity by distinct mechanisms
2002
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
The CtsR regulator of stress response is active as a dimer and specifically degraded in vivo at 37°C
2000
Compartmentalized gene expression during sporulation in Bacillus subtilis
1991
Interactions of the M. tuberculosis UsfX with the cognate sigma factor SigF and the anti-anti sigma factor RsfA
2008
Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics
1990
Histidine kinases and response regulators in networks
2011
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Cloning of a human gene encoding the general transcription initiation factor IIB
1991 Nature
Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling
2007
Cyclic Dinucleotides and the Innate Immune Response
2013
Bacterial stress responses as determinants of antimicrobial resistance
2012
Molecular imaging of hydrogen peroxide produced for cell signaling
2007
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Crystal Structure of Thermus aquaticus Core RNA Polymerase at 3.3 Å Resolution
1999
NRF2 and cancer: the good, the bad and the importance of context
2012
The third pillar of bacterial signal transduction: classification of the extracytoplasmic function (ECF) σ factor protein family
2009
Three-dimensional structure of E. coil core RNA polymerase: Promoter binding and elongation conformations of the enzyme
1995
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
A universal biomolecular integral feedback controller for robust perfect adaptation
2019 Nature
REGULATION OF BACTERIAL OXIDATIVE STRESS GENES
1991
CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria
1999
ClpE, a novel type of HSP100 ATPase, is part of the CtsR heat shock regulon of Bacillus subtilis
1999
Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: A mechanism for differential promoter selection
1994
Isolation of the gene encoding the yeast TATA binding protein TFIID: A gene identical to the SPT15 suppressor of Ty element insertions
1989
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
1995 StandoutNobel
Extra cytoplasmic function σ factor activation
2012
Synthetic, Switchable Enzymes
2017
Analysis of structure-function relationships of yeast TATA box binding factor TFIID
1990
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo
1992
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Crisscross regulation of cell-type-specific gene expression during development in B. subtilis
1992 Nature
Regulation of bacterial RNA polymerase σ factor activity: a structural perspective
2008
Abortive Initiation by Saccharomyces cerevisiae RNA Polymerase III
1999
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
2007 Standout
The extracytoplasmic function sigma factors: role in bacterial pathogenesis
2004
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
GENETICS AND BIOGENESIS OF BACTERIAL FLAGELLA
1992
The intercalating β-hairpin of T7 RNA polymerase plays a role in promoter DNA melting and in stabilizing the melted DNA for efficient RNA synthesis
2002
Structure of the Bacterial RNA Polymerase Promoter Specificity σ Subunit
2002
Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling
2003
Interactions of anti-sigma factor antagonists of Mycobacterium tuberculosis in the yeast two-hybrid system
2005
The Role of Zinc in the Disulphide Stress-regulated Anti-sigma Factor RsrA from Streptomyces coelicolor
2003
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Bacterial redox sensors
2004
An obesity-associated gut microbiome with increased capacity for energy harvest
2006 StandoutNature
Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration
2004
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
1994 Standout
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
Structural Organization of Bacterial RNA Polymerase Holoenzyme and the RNA Polymerase-Promoter Open Complex
2002
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Bacterial RNA polymerases: the wholo story
2003
Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid
2008
Mapping of Rpb3 and Rpb5 contact sites on two large subunits, Rpb1 and Rpb2, of the RNA polymerase II from fission yeast
1998
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
2010 Standout
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase
2004 StandoutNobel
Polyphosphate Is a Primordial Chaperone
2014
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus
2006
Microbial H2O2 sensors as archetypical redox signaling modules
2004
A synthetic multicellular system for programmed pattern formation
2005 StandoutNatureNobel
Electron Crystal Structure of an RNA Polymerase II Transcription Elongation Complex
1999 StandoutNobel
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized
1999
Hydrogen Peroxide: A Signaling Messenger
2006 Standout
Zinc Center as Redox Switch—New Function for an Old Motif
2006
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Assignment of the Zinc Ligands in RsrA, a Redox-Sensing ZAS Protein from Streptomyces coelicolor
2006
Detecting Subtle Sequence Signals: a Gibbs Sampling Strategy for Multiple Alignment
1993 Science
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
1993
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
2008 Science
Mechanism of promoter selection by RNA polymerase II: mammalian transcription factors alpha and beta gamma promote entry of polymerase into the preinitiation complex.
1991
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Events during Initiation of Archaeal Transcription: Open Complex Formation and DNA-Protein Interactions
2001
Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
2004 StandoutScienceNobel
Complex Regulation of the Organic Hydroperoxide Resistance Gene ( ohr ) from Xanthomonas Involves OhrR, a Novel Organic Peroxide-Inducible Negative Regulator, and Posttranscriptional Modifications
2001
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
Interactions of Escherichia coli σ 70 within the transcription elongation complex
1999
Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling
2003
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
2009
An iron-sulfur center essential for transcriptional activation by the redox-sensing SoxR protein.
1994
A possible role for the yeast TATA-element-binding protein in DNA replication.
1993
Promoter Recognition As Measured by Binding of Polymerase to Nontemplate Strand Oligonucleotide
1997 Science
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Tools and Tactics for the Optical Detection of Mercuric Ion
2008 Standout
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase
1992 StandoutScienceNobel
Characterization of a gene controlling heterocyst differentiation in the cyanobacterium Anabaena 7120.
1991
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth.
1989
Cysteine Oxidative Posttranslational Modifications
2013
RNA-binding proteins as developmental regulators.
1989
Generation of catalytic RNAs by rolling transcription of synthetic DNA nanocircles
1997
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
THE ANTI-SIGMA FACTORS
1998
The General Transcription Factor RAP30 Binds to RNA Polymerase II and Prevents It from Binding Nonspecifically to DNA
1992
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
The T7 RNA Polymerase Intercalating Hairpin Is Important for Promoter Opening during Initiation but Not for RNA Displacement or Transcription Bubble Stability during Elongation
2001
RNA Polymerase II Subunit RPB4 Is Essential for High- and Low-Temperature Yeast Cell Growth
1989
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators
1994 Standout
An RNA Polymerase-Binding Protein That Is Required for Communication Between an Enhancer and a Promoter
1990 Science
Protein Sulfenic Acids in Redox Signaling
2004
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length
2002
Works of John D. Helmann being referenced
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli
2010
The OhrR repressor senses organic hydroperoxides by reversible formation of a cysteine-sulfenic acid derivative
2002
Analysis of the role ofBacillus subtilisσMin β‐lactam resistance reveals an essential role for c‐di‐AMP in peptidoglycan homeostasis
2011
The extracytoplasmic function (ECF) sigma factors
2002
Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury(II) binding domains
1989
Anti-sigma factors
1999
Biochemical Characterization of the Structural Zn2+ Site in the Bacillus subtilis Peroxide Sensor PerR
2006
Pathway of promoter melting by Bacillus subtilis RNA polymerase at a stable RNA promoter: Effects of temperature, .delta. protein, and .sigma. factor mutations
1995
The sigma70 family of sigma factors.
2003
Mutations in Sigma Factor That Affect the Temperature Dependence of Transcription from a Promoter, but Not from a Mismatch Bubble, in Double-Stranded DNA
1994
Alternative sigma factors and the regulation of flagellar gene expression
1991
Defining the Bacillus subtilis σW regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches
2002
The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility σ factor of B. subtilis
1989
The δ Subunit of Bacillus subtilis RNA Polymerase
1994
STRUCTURE AND FUNCTION OF BACTERIAL SIGMA FACTORS
1988
TheBacillus subtilisFlagellar Regulatory Protein σD: Overproduction, Domain Analysis and DNA-binding Properties
1995
The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation
2006 Nature
Structure of an OhrR-ohrA Operator Complex Reveals the DNA Binding Mechanism of the MarR Family
2005
The Bacillus subtilisσM regulon and its contribution to cell envelope stress responses
2008
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon
2003
A peroxide‐induced zinc uptake system plays an important role in protection against oxidative stress in Bacillus subtilis
2002
The A. tumefaciens transcriptional activator OccR causes a bend at a target promoter, which is partially relaxed by a plant tumor metabolite
1992
Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilisσW and σM regulons
2002
Bacillus subtilis extracytoplasmic function (ECF) sigma factors and defense of the cell envelope
2016
A Promoter Melting Region in the Primary σ Factor of Bacillus subtilis
1994
Compilation and analysus ofBacillus SubtilisσA-dependent promoter sequences: evidence for extended contact between RNA polymerse and upstream promoter DNA
1995
Thiol-Based Redox Switches and Gene Regulation
2010
Protein−Nucleic Acid Interactions during Open Complex Formation Investigated by Systematic Alteration of the Protein and DNA Binding Partners
1999
Regulation of the Bacillus subtilis Extracytoplasmic Function Protein σ Y and Its Target Promoters
2003
The MerR Metalloregulatory Protein Binds Mercuric Ion as a Tricoordinate, Metal-Bridged Dimer
1990 Science
Contributions of the σW , σM and σX regulons to the lantibiotic resistome of B acillus subtilis
2013
A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR
2007
Antibiotic-Inducible Promoter Regulated by the Cell Envelope Stress-Sensing Two-Component System LiaRS of Bacillus subtilis
2004
Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes
1996
Promoter Recognition by Bacillus subtilis ς W : Autoregulation and Partial Overlap with the ς X Regulon
1998
OxyR: A Molecular Code for Redox Sensing?
2002
Stimulus Perception in Bacterial Signal-Transducing Histidine Kinases
2006
Deciphering a Complex Genetic Regulatory Network: The Bacillus Subtilis σW Protein and Intrinsic Resistance to Antimicrobial Compounds
2006
DNA-melting at the Bacillus subtilis flagellin promoter nucleates near −10 and expands unidirectionally
1997
Open complex formation by Escherichia coli RNA polymerase: the mechanism of polymerase‐induced strand separation of double helical DNA
1995
Regulatory Overlap and Functional Redundancy amongBacillus subtilisExtracytoplasmic Function σ Factors
2007
FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant
1996
Regulation of the Bacillus subtilis bcrC Bacitracin Resistance Gene by Two Extracytoplasmic Function σ Factors
2002
Genetic and physiological studies of Bacillus subtilis sigma A mutants defective in promoter melting
1994
The Global Transcriptional Response ofBacillus subtilisto Peroxide Stress Is Coordinated by Three Transcription Factors
2002
Regulation of inducible peroxide stress responses
2002
Mutations in Multidrug Efflux Homologs, Sugar Isomerases, and Antimicrobial Biosynthesis Genes Differentially Elevate Activity of the ς X and ς W Factors in Bacillus subtilis
2000
Regulation of LiaRS-Dependent Gene Expression inBacillus subtilis: Identification of Inhibitor Proteins, Regulator Binding Sites, and Target Genes of a Conserved Cell Envelope Stress-Sensing Two-Component System
2006
The Bacillus subtilis Extracytoplasmic-Function σ X Factor Regulates Modification of the Cell Envelope and Resistance to Cationic Antimicrobial Peptides
2004
Response ofBacillus subtilisto Nitric Oxide and the Nitrosating Agent Sodium Nitroprusside
2004
OhrR Is a Repressor of ohrA , a Key Organic Hydroperoxide Resistance Determinant in Bacillus subtilis
2001
Homologous metalloregulatory proteins from both gram-positive and gram-negative bacteria control transcription of mercury resistance operons
1989
Cloning, sequencing, and disruption of the Bacillus subtilis sigma 28 gene
1988
Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA
2001
A mismatch bubble in double-stranded DNA suffices to direct precise transcription initiation by Escherichia coli RNA polymerase.
1994
Bacterial Ohr and OsmC paralogues define two protein families with distinct functions and patterns of expression
2001
DNA sequence analysis suggests that expression of flagellar and chemotaxis genes in Escherichia coli and Salmonella typhimurium is controlled by an alternative sigma factor.
1987
Structure And Function Of Bacterial Sigma Factors
1988