Standout Papers
Citation Impact
Citing Papers
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Some Factors in the Interpretation of Protein Denaturation
1959 Standout
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
1985 StandoutNatureNobel
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
From molecular to modular cell biology
1999 StandoutNatureNobel
Funnels, pathways, and the energy landscape of protein folding: A synthesis
1995 Standout
A route to high surface area, porosity and inclusion of large molecules in crystals
2004 StandoutNatureNobel
Dominant forces in protein folding
1990 Standout
From Levinthal to pathways to funnels
1997 Standout
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Effects of Na+ on the persistence length and excluded volume of T7 bacteriophage DNA
1991
Minimal model systems for β-sheet secondary structure in proteins
1998
Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding
2008
The chemistry of scrapie infection: implications of the ‘ice 9’ metaphor
1995
Structure of the recA protein–ADP complex
1992 StandoutNatureNobel
The energy landscape of a fast-folding protein mapped by Ala→Gly Substitutions
1997
Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3
1988 Nature
Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G
1992
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Denaturant m values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding
1995 Standout
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
Secondary structure determines protein topology
2006
Protein folding in the landscape perspective: Chevron plots and non-arrhenius kinetics
1998
A mutant T4 lysozyme displays five different crystal conformations
1990 Nature
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
Folding of a four-helix bundle: studies of acyl-coenzyme A binding protein
1995
The coming of age of de novo protein design
2016 StandoutNatureNobel
Circular dichroic analysis of protein conformation: Inclusion of the β-turns
1978
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Glutamine, alanine or glycine repeats inserted into the loop of a protein have minimal effects on stability and folding rates
1997
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Nanofabricated media with negative permeability at visible frequencies
2005 StandoutNatureNobel
Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme
1992
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene
1992 Nature
A comparison of the folding kinetics and thermodynamics of two homologous fibronectin type III modules
1997
Extremely rapid protein folding in the absence of intermediates
1995
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl .alpha.-chymotrypsin using different denaturants
1988
The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations
1999
Structure and Stability of Monomeric .lambda. Repressor: NMR Evidence for Two-State Folding
1995
Lessons from the lysozyme of phage T4
2010
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Effective energy function for proteins in solution
1999
A protein-folding reaction under kinetic control
1992 StandoutNatureNobel
Secondary structure content of the HDV ribozyme in 95% formamide
1996
Molecular collapse: The rate-limiting step in two-state cytochrome c folding
1996
Mapping the transition state and pathway of protein folding by protein engineering
1989 Nature
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Do all backbone polar groups in proteins form hydrogen bonds?
2005
How to measure and predict the molar absorption coefficient of a protein
1995 Standout
Contact order, transition state placement and the refolding rates of single domain proteins 1 1Edited by P. E. Wright
1998 StandoutNobel
Preorganized secondary structure as an important determinant of fast protein folding.
2001
Stability and stabilization of globular proteins in solution
2000
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure
1989 Standout
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Protein folding dynamics: The diffusion‐collision model and experimental data
1994
Measurement of the β-sheet-forming propensities of amino acids
1994 Nature
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity
2010
Structural patterns in globular proteins
1976 StandoutNatureNobel
Testing models of the arrangement of DNA inside bacteriophage λ by crosslinking the packaged DNA
1982
Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity
1978 Standout
The Preparation of Subtilisin-modified Ribonuclease and the Separation of the Peptide and Protein Components
1959
Protein Folding Dynamics: Quantitative Comparison between Theory and Experiment
1998
The molecular theory of polyelectrolyte solutions with applications to the electrostatic properties of polynucleotides
1978 Standout
Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability
1997 StandoutNobel
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
Electronic Spectra of Isoelectronic Amides, Acids, and Acyl Fluorides
1968
Cooperative Conformational Transitions in Phenylene Ethynylene Oligomers: Chain-Length Dependence
1999
Enzymatic Synthesis of Deoxyribonucleic Acid
1969
DNA packaging by the double-stranded DNA bacteriophages
1980
Protein folding
1990
Effect of Urea on Trypsin and Alpha-Chymotrypsin
1956 Nature
Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures
1999 StandoutNobel
DNA arrangement in isometric phage heads
1977 Nature
Response of a Protein Structure to Cavity-Creating Mutations and Its Relation to the Hydrophobic Effect
1992 Science
Tests of spool models for DNA packaging in phage lambda
1983
Internal Stark Effect Measurement of the Electric Field at the Amino Terminus of an α Helix
1992 Science
Submillisecond folding of monomeric lambda repressor.
1995
Self—Consistent Molecular Orbital Methods. XII. Further Extensions of Gaussian—Type Basis Sets for Use in Molecular Orbital Studies of Organic Molecules
1972 StandoutNobel
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Nucleation, Rapid Folding, and Globular Intrachain Regions in Proteins
1973
Crystal Structure of the Aequorea victoria Green Fluorescent Protein
1996 StandoutScienceNobel
How many base-pairs per turn does DNA have in solution and in chromatin? Some theoretical calculations.
1978 StandoutNobel
Theory of cooperative transitions in protein molecules. II. Phase diagram for a protein molecule in solution
1989
Substrate stabilization of lysozyme to thermal and guanidine hydrochloride denaturation.
1980
De Novo Protein Design: Fully Automated Sequence Selection
1997 Science
On the Conformational Stability of Globular Proteins
1965
Conformational studies on peptides—I
1971
Supercoiling energy and nucleosome formation: the role of the arginine-rich histone kernel
1977
Studies on the Antigenic Structure of Ribonuclease
1962
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
Sequence and structure of D-glyceraldehyde 3-phosphate dehydrogenase from Bacillus stearothermophilus
1977 StandoutNatureNobel
Possibility of nonkinked packing of DNA in chromatin.
1978
Recognition and Stabilization of an α-Helical Peptide by a Synthetic Receptor
1997
The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
1998 StandoutScienceNobel
Temperature dependence of the hydrophobic interaction in protein folding.
1986
Partial NH2- and cooh-terminal sequence analyses of Eco RI DNA restriction and modification enzymes.
1981 StandoutNobel
Arrangement of double-stranded DNA packaged in bacteriophage capsids
1986
Organization of double-stranded DNA in bacteriophages: a study by cryo-electron microscopy of vitrified samples.
1987 StandoutNobel
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Alkylation of the Methionine Residues of Ribonuclease in 8 m Urea
1964 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Investigation of the flexibility of DNA using transient electric birefringence
1981
The α-helix folds on the millisecond time scale
1999
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Electronic States of the Amide Group
1967
IMMUNOCHEMICAL REACTIONS INVOLVING RIBONUCLEASE*
1959
Characterization of a Helical Protein Designed from First Principles
1988 Science
Diffusion control in an elementary protein folding reaction
1997
THE LIMITED DIGESTION OF RIBONUCLEASE WITH PEPSIN
1956 StandoutNobel
Spectrophotometric and stoichiometric titrations of ribonuclease in eight molar urea
1958
Studies on the subunit structure of thermostable glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus
1970
Structure of nucleosome core particles of chromatin
1977 StandoutNatureNobel
Studies on the Antigenic Structure of Ribonuclease
1963 StandoutNobel
Protein denaturation. C. Theoretical models for the mechanism of denaturation.
1970 Standout
Stabilization of phage T4 lysozyme by engineered disulfide bonds.
1989
Molecular Light Scattering and Optical Activity
2004
CONTROLLED PROTEOLYSIS OF NASCENT POLYPEPTIDES IN RAT LIVER CELL FRACTIONS
1970 StandoutNobel
Interaction of recA protein with single-stranded DNA
1985
Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules
1996 StandoutScience
Some Factors Which Affect the Enzymatic Digestion of Ribonucleic Acid
1959
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Anisotropic flexibility of DNA and the nucleosomal structure
1979
Kinetics and Dynamics of Loops, α-Helices, β-Hairpins, and Fast-Folding Proteins
1998
Dyeing Crystals
2001
Structure of bacteriophage T4 lysozyme refined at 1.7 Å resolution
1987
Hydrogen bonding and biological specificity analysed by protein engineering
1985 StandoutNatureNobel
RNA structure
1977
Separate GTP Binding and GTPase Activating Domains of a Gα Subunit
1993 Science
THE REACTION OF O-METHYLISOUREA WITH BOVINE PANCREATIC RIBONUCLEASE
1957
Optical Activity of Bile Pigments
1983
Barriers to protein folding: formation of buried polar interactions is a slow step in acquisition of structure.
1996
Works of John A. Schellman being referenced
The thermodynamics of solvent exchange
1994
Folding kinetics of T4 lysozyme and nine mutants at 12 .degree.C
1992
Low-temperature unfolding of a mutant of phage T4 lysozyme. 1. Equilibrium studies
1989
Low-temperature unfolding of a mutant of phage T4 lysozyme. 2. Kinetic investigations
1989
Temperature, stability, and the hydrophobic interaction
1997
Static contributions to the persistence length of DNA and dynamic contributions to DNA curvature
1995
Large differences in the helix propensities of alanine and glycine
1991 Nature
Optical spectroscopy of oriented molecules
1987
Helix-coil theories: a comparative study for finite length polypeptides
1992
Advances in Protein Chemistry.
1957
Studies on the structural basis of ribonuclease activity
1955 StandoutNobel
Cooperative Multisite Binding to DNA
1974
The Thermal Transition of Ribonuclease in Urea Solutions
1959
Location of proline derivatives in conformational space. II. Theoretical optical activity
1970
Stability of phage T4 lysozymes I. Native properties and thermal stability of wild type and two mutant lysozymes
1977
Flexibility of DNA
1974
The flow linear dichroism of DNA: Comparison with the bead‐spring theory
1978
Selective binding and solvent denaturation
1987
The Factors Affecting the Stability of Hydrogen-bonded Polypeptide Structures in Solution
1958
The interaction of ribonuclease with purine and pyrimidine phosphates I. Binding of adenosine 5′-monophosphate to ribonuclease
1962
Optical activity of polypeptides and proteins
1972
Flow dichroism of capsid DNA phages. II. Effect of DNA deletions and intercalating dyes
1982
Location of proline derivatives in conformational space. I. Conformational calculations; optical activity and NMR experiments
1970
The Application of the Bjerrum Ion Association Theory to the Binding of Anions by Proteins
1953
The n—π* Cotton Effect of the Peptide Linkage
1965
Vibrational optical activity
1973
Phage T4 lysozyme Physical properties and reversible unfolding
1975
The absorption spectra of simple amides and peptides
1967
Thermodynamic stability and point mutations of bacteriophage T4 lysozyme
1984
Origin of the Cotton Effect of Helical Polypeptides
1962
Flow dichroism of T7 DNA as a function of salt concentration
1981
Protein stability curves
1987
DNA condensation with polyamines
1978
Advances in Protein Chemistry.
1960
Flow dichroism of capsid DNA phages. I. Fast and slow T4B
1982
The stability of hydrogen-bonded peptide structures in aqueous solution.
1955
Solvent denaturation
1978
Symmetry rules for optical rotation
1968
Compact form of DNA induced by spermidine
1976 Nature
Spectra of amides. Theoretical considerations
1967
Solvent effects on dinucleotide conformation
1972
THE THERMODYNAMIC STABILITY OF PROTEINS
1987
Macromolecular binding
1975
Stability of phage T4 lysozomes
1979
The effect of binding on the melting temperature of biopolymers
1976
DNA condensation with polyamines
1978
Measurement of Ultraviolet Indices of Refraction with a Differental Refractometer.
1964
The Structure of insulin as compared to that of Sanger's A-chain
1954