Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process
2004
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Small-molecule modulators of the Sonic Hedgehog signaling pathway
2009
Glycoproteomic analysis of tissues from patients with colon cancer using lectin microarrays and nanoLC-MS/MS
2013
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
2012 Standout
Perlecan controls neurogenesis in the developing telencephalon
2007
Differential range and activity of various forms of the Hedgehog protein
2005
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Hedgehog: functions and mechanisms
2008 Standout
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates
2004
A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord
2002
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
2003 StandoutNature
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification
2002
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics
2010
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Hedgehog signalling in the mouse requires intraflagellar transport proteins
2003 StandoutNature
Drosophila Wnt-1 Undergoes a Hydrophobic Modification and Is Targeted to Lipid Rafts, a Process That Requires Porcupine
2004
Incredible journey: how do developmental signals travel through tissue?
2004
Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development
2004
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Patched acts catalytically to suppress the activity of Smoothened
2002 Nature
Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling
2013
The hedgehog signaling network
2003
Communicating with Hedgehogs
2005
Sonic hedgehog in CNS development: one signal, multiple outputs
2002
Regulated portals of entry into the cell
2003 StandoutNature
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Core fucosylation and 2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia
2010
Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia
2013
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
2005
Glycans as cancer biomarkers
2011
G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling
2008 Nature
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract
2007
Hhat Is a Palmitoylacyltransferase with Specificity for N-Palmitoylation of Sonic Hedgehog
2008
Developments in the Identification of Glycan Biomarkers for the Detection of Cancer
2013
Determination of glycosylation sites and site-specific heterogeneity in glycoproteins
2009
Wnt/β-Catenin Signaling and Disease
2012 Standout
Release and trafficking of lipid-linked morphogens
2005
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Glycomics and disease markers
2009
Mammalian Wnt3a is Released on Lipoprotein Particles
2009
SNAREs — engines for membrane fusion
2006 Standout
Revealing the human mucinome
2022 StandoutNobel
Morphogen gradient interpretation by a regulated trafficking step during ligand–receptor transduction
2005 StandoutNobel
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
2009 Standout
Hedgehog-Mediated Patterning of the Mammalian Embryo Requires Transporter-like Function of Dispatched
2002
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Analytical glycobiology at high sensitivity: current approaches and directions
2012
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Lectin-Based Glycoproteomic Techniques for the Enrichment and Identification of Potential Biomarkers
2010
Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment
2004
New developments in the discovery of small molecule Hedgehog pathway antagonists
2010
A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
2007 Standout
The N-glycome of human embryonic stem cells
2009
Chapter 13 Long‐Range Gene Control and Genetic Disease
2008
Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function
2005
Adipocyte differentiation from the inside out
2006 Standout
When cell biology meets development: endocytic regulation of signaling pathways
2002
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
2009
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
A Comprehensive Benchmark Study of Multiple Sequence Alignment Methods: Current Challenges and Future Perspectives
2011
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Glycans and glycoproteins as specific biomarkers for cancer
2016
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
Spatial partitioning of the regulatory landscape of the X-inactivation centre
2012 StandoutNature
Nodal Flow and the Generation of Left-Right Asymmetry
2006
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
2004 Standout
Regulation and Function of the Sonic Hedgehog Signal Transduction Pathway in Isolated Gastric Parietal Cells
2005
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila
2008
A paracrine requirement for hedgehog signalling in cancer
2008 Nature
The ascites N-glycome of epithelial ovarian cancer patients
2017
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
Exosomes
2019 Standout
Mice Deficient in the Fused Homolog Do Not Exhibit Phenotypes Indicative of Perturbed Hedgehog Signaling during Embryonic Development
2005
Glycoproteomics-Based Identification of Cancer Biomarkers
2011
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Cell surface protein glycosylation in cancer
2013
Cholesterol modification restricts the spread of Shh gradient in the limb bud
2006
Model organisms lead the way to protein palmitoyltransferases
2004
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog inDrosophilaepithelia
2006
Novel Lipid Modifications of Secreted Protein Signals
2004
Suppressor of Fused Regulates Gli Activity through a Dual Binding Mechanism
2004
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left–right determination
2005 Nature
Sweetening the Pot: Adding Glycosylation to the Biomarker Discovery Equation
2009
Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting
2010
Small molecule modulation of Smoothened activity
2002 Standout
Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2
2006 StandoutNobel
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
2008
Exosomes in developmental signalling
2016
Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix
2006
Alterations in the Serum Glycome Due to Metastatic Prostate Cancer
2007
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Glycoproteomic Analysis of Malignant Ovarian Cancer Ascites Fluid Identifies Unusual Glycopeptides
2016
Using lectins to harvest the plasma/serum glycoproteome
2012
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Functions of heparan sulfate proteoglycans in cell signaling during development
2004
Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega
2011 Standout
Exploring the glycoproteomics landscape with advanced MS technologies
2014
Regulatory Principles of Developmental Signaling
2002 StandoutNobel
Glycobioinformatics: Current strategies and tools for data mining in MS ‐based glycoproteomics
2012
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Quantitative mass spectrometric analysis of glycoproteins combined with enrichment methods
2014
Works of John A. Goetz being referenced
Glycomic and Proteomic Profiling of Pancreatic Cyst Fluids Identifies Hyperfucosylated Lactosamines on the N-linked Glycans of Overexpressed Glycoproteins
2012
Glycomic profiling of invasive and non-invasive breast cancer cells
2008
The Kinesin-related Protein Costal2 Associates with Membranes in a Hedgehog-sensitive, Smoothened-independent Manner
2004
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma
2006
Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner
2008
A freely diffusible form of Sonic hedgehog mediates long-range signalling
2001 Nature
Shh signaling in limb bud ectoderm: Potential role in teratogen‐induced postaxial ectrodactyly
2005
Smoking and lung cancer-induced changes in N-glycosylation of blood serum proteins
2012
Sonic Hedgehog as a mediator of long‐range signaling*
2002
A Highly Conserved Amino-terminal Region of Sonic Hedgehog Is Required for the Formation of Its Freely Diffusible Multimeric Form
2005
Breast Cancer Diagnosis and Prognosis through Quantitative Measurements of Serum Glycan Profiles
2008
N-linked Glycan Structures and Their Expressions Change in the Blood Sera of Ovarian Cancer Patients
2012
Comparative Profiling of N-Glycans Isolated from Serum Samples of Ovarian Cancer Patients and Analyzed by Microchip Electrophoresis
2013
Examination of Glycan Profiles from IgG-Depleted Human Immunoglobulins Facilitated by Microscale Affinity Chromatography
2012
Comparative Glycomic Mapping through Quantitative Permethylation and Stable-Isotope Labeling
2007
Enzymatic/Chemical Release of O-Glycans Allowing MS Analysis at High Sensitivity
2009
Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud
2003