Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
G protein-coupled receptors: In silico drug discovery in 3D
2004
Distinct Binding Specificity of the Multiple PDZ Domains of INADL, a Human Protein with Homology to INAD from Drosophila melanogaster
2001
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity
2011
PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening
2013
Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain
2001
Analysis of PDZ Domain-Ligand Interactions Using Carboxyl-terminal Phage Display
2000
CRIPT, a Novel Postsynaptic Protein that Binds to the Third PDZ Domain of PSD-95/SAP90
1998
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of β2-syntrophin and nNOS in pancreatic β-cells
2000
Fragment-based lead discovery
2004
A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast
2002 StandoutNobel
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
PDZ Domains: Structural Modules for Protein Complex Assembly
2002
Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide.
1999
Physiological roles of axonal ankyrins in survival of premyelinated axons and localization of voltage-gated sodium channels
1999
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Chemical ligation of unprotected peptides directly from a solid support
1998
Φ-Analysis at the Experimental Limits: Mechanism of β-Hairpin Formation
2006
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists
2005 StandoutNobel
The PDZ Binding Motif of the β1 Adrenergic Receptor Modulates Receptor Trafficking and Signaling in Cardiac Myocytes
2002 StandoutNobel
Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
1998
Photonic structures in biology
2003 StandoutNature
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Quantification of PDZ Domain Specificity, Prediction of Ligand Affinity and Rational Design of Super-binding Peptides
2004
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Diffusion NMR Spectroscopy in Supramolecular and Combinatorial Chemistry: An Old Parameter—New Insights
2004
Interaction of Serotonin 5-Hydroxytryptamine Type 2C Receptors with PDZ10 of the Multi-PDZ Domain Protein MUPP1
2001
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
NMR Studies on the Diffusion of Hydrocarbons on the Metal‐Organic Framework Material MOF‐5
2006 StandoutNobel
Origins of PDZ Domain Ligand Specificity
2003
Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways
2012
Structural basis for phosphoserine-proline recognition by group IV WW domains.
2000
Conformation of the RNA polymerase II C-terminal domain: circular dichroism of long and short fragments
2000
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
Molecular Roots of Degenerate Specificity in Syntenin's PDZ2 Domain
2003
PSD-95 Assembles a Ternary Complex with theN-Methyl-d-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain
1999
The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC
1997 StandoutNobel
G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95
2002 StandoutNobel
PDZ domains – glue and guide
2003
Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79
2001 StandoutNobel
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
A Novel Multiple PDZ Domain-containing Molecule Interacting withN-Methyl-d-aspartateReceptors and Neuronal Cell Adhesion Proteins
1998 StandoutNobel
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
Sequence determinants of thermodynamic stability in a WW domain—An all‐β‐sheet protein
2009
MAGI-1, a Membrane-associated Guanylate Kinase with a Unique Arrangement of Protein-Protein Interaction Domains
1997
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Solution Structure of the RIM1α PDZ Domain in Complex with an ELKS1b C-terminal Peptide
2005 StandoutNobel
Three-dimensional segregation of supramolecular activation clusters in T cells
1998 StandoutNature
Seven-transmembrane receptors
2002 StandoutNobel
Structure and function of the WW domain
1996
β1-Adrenergic Receptor Association with PSD-95
2000 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Specific Role of the Truncated βIV-Spectrin Σ6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
2006 StandoutNobel
Identification of Novel Human WW Domain-containing Proteins by Cloning of Ligand Targets
1997
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
A PDZ-containing Scaffold Related to the Dystrophin Complex at the Basolateral Membrane of Epithelial Cells
1999
Adjustable Receptor Based on a [3]Rotaxane Whose Two Threaded Rings Are Rigidly Attached to Two Porphyrinic Plates: Synthesis and Complexation Studies
2009 StandoutNobel
The Drosophila melanogaster Suppressor of deltex Gene, a Regulator of the Notch Receptor Signaling Pathway, Is an E3 Class Ubiquitin Ligase
1999
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
SAP97 interacts with Kv1.5 in heterologous expression systems
2001
Organization of Signaling Complexes by PDZ-Domain Scaffold Proteins
2003
Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of nNOS-Syntrophin Complex
1999 Science
MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALING
1997
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones
2002 StandoutNobel
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
The Structure and Function of Proline Recognition Domains
2003
Crystal structure of the TSP-1 type 1 repeats
2002
In vivo requirement of the α-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4
2001
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
The role of individual Nedd4–2 (KIAA0439) WW domains in binding and regulating epithelial sodium channels
2002
Mechanism and role of PDZ domains in signaling complex assembly
2001
Delayed K + clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice
2003 StandoutNobel
Diffusions‐NMR‐Spektroskopie in der Supramolekularen und Kombinatorischen Chemie: ein alter Parameter – neue Erkenntnisse
2004
FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands
1997
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Absence of α-Syntrophin Leads to Structurally Aberrant Neuromuscular Synapses Deficient in Utrophin
2000
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein
2001 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
The Use of In Vitro Peptide-Library Screens in the Analysis of Phosphoserine/Threonine-Binding Domain Structure and Function
2004
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
PDZ Domains and the Organization of Supramolecular Complexes
2001
De novo design of protein logic gates
2020 StandoutScienceNobel
Spectrin and Ankyrin-Based Pathways: Metazoan Inventions for Integrating Cells Into Tissues
2001
Works of Johan Schultz being referenced
Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B)
2004
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide
1996 Nature
Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels
1998
Structure-based screening and design in drug discovery
2002
Structure-Based Screening As Applied to Human FABP4: A Highly Efficient Alternative to HTS for Hit Generation
2002