Standout Papers

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP 1998 2026 2007 2016 1.6k
  1. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP (1998)
    Johan de Rooij, Fried Zwartkruis et al. Nature
  2. A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK (2002)
    Jorrit M. Enserink, Anne Elisabeth Christensen et al. Nature Cell Biology
  3. Rap1 signalling: adhering to new models (2001)
    Johannes L. Bos, Johan de Rooij et al. Nature Reviews Molecular Cell Biology

Immediate Impact

26 by Nobel laureates 32 from Science/Nature 67 standout
Sub-graph 1 of 19

Citing Papers

Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
2 intermediate papers

Works of Johan de Rooij being referenced

Mechanosensitive systems at the cadherin–F-actin interface
2013
Rap1 signalling: adhering to new models
2001 Standout
and 1 more

Author Peers

Author Last Decade Papers Cites
Johan de Rooij 5618 3040 1124 61 8.6k
Keigi Fujiwara 4265 2951 847 116 7.9k
Catherine D. Nobes 6621 4569 1643 48 10.2k
Carlo Tacchetti 5108 2563 855 122 8.5k
Michael D. Henry 5379 1504 1012 104 8.2k
Kazushi Kimura 5278 2956 883 44 8.6k
Stefan Butz 4544 1849 670 66 7.4k
John G. Collard 6853 3985 1705 73 9.6k
Arthur D. Lander 6195 4011 1445 132 9.9k
Arthur S. Alberts 4187 3295 772 66 7.1k
David T. Shima 7664 2158 624 82 11.8k

All Works

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2026