Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
2011
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
2017 StandoutNobel
Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver
2005
The long-term benefits of nucleos(t)ide analogs in compensated HBV cirrhotic patients with no or small esophageal varices: A 12-year prospective cohort study
2015
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity
2013
Interferón en la hepatitis B
2008
Hepatitis B Virus Infection — Natural History and Clinical Consequences
2004 Standout
A Randomized, Open-Label Clinical Study of Combined Pegylated Interferon Alfa-2a (40KD) and Entecavir Treatment for Hepatitis B "e" Antigen-Positive Chronic Hepatitis B
2014
First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B
2016
Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis
2013
Effects of Tenofovir Disoproxil Fumarate in Hepatitis B e Antigen-Positive Patients With Normal Levels of Alanine Aminotransferase and High Levels of Hepatitis B Virus DNA
2014
Hepatocellular carcinoma
2018 Standout
Control of cccDNA function in hepatitis B virus infection
2009
Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion
2003
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Antiviral Therapy of Chronic Hepatitis B: Prevention of Drug Resistance
2007
Experimental models and therapeutic approaches for HBV
2012
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Generation of improved humanized mouse models for human infectious diseases
2014
Assessment of Chimeric Mice with Humanized Liver as a Tool for Predicting Circulating Human Metabolites
2010
Mice With Human Livers
2013
Reduction of Infectivity in Chronic Hepatitis B Virus Carriers among Healthcare Providers and Pregnant Women by Antiviral Therapy
2014
Liver‐Stage Development ofPlasmodium falciparum,in a Humanized Mouse Model
2006
New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus
2016
Hepatitis C virus replication in mice with chimeric human livers
2001
New insight in the pathobiology of hepatitis B virus infection
2012
Organoid Models and Applications in Biomedical Research
2015 Standout
Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone
2004
Shared and Distinct Functions of Type I and Type III Interferons
2019
Switching from entecavir to PegIFN alfa-2a in patients with HBeAg-positive chronic hepatitis B: A randomised open-label trial (OSST trial)
2014
The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo
2014
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Hepatitis B cure: From discovery to regulatory approval
2017
DNA cleavage enzymes for treatment of persistent viral infections: Recent advances and the pathway forward
2014
Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice
2009
Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice
2006
The role of quantitative hepatitis B surface antigen revisited
2016
Advances in experimental systems to study hepatitis C virus in vitro and in vivo
2015
An Efficient Antiviral Strategy for Targeting Hepatitis B Virus Genome Using Transcription Activator-Like Effector Nucleases
2013
Resistance surveillance in chronic hepatitis B patients treated with adefovir dipivoxil for up to 60 weeks
2002
Generation of hybrid hepatocytes by cell fusion from monkey embryoid body cells in the injured mouse liver
2005
Novel Robust in Vitro Hepatitis B Virus Infection Model Using Fresh Human Hepatocytes Isolated from Humanized Mice
2015
Decay of ccc-DNA marks persistence of intrahepatic viral DNA synthesis under tenofovir in HIV-HBV co-infected patients
2016
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
2007
EXPRESSION OF HUMAN CYTOCHROMES P450 IN CHIMERIC MICE WITH HUMANIZED LIVER
2004
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia.
1994
Near Completely Humanized Liver in Mice Shows Human-Type Metabolic Responses to Drugs
2004
Prolonged engraftment of human hepatocytes in mice transgenic for the deleted form of human hepatocyte growth factor
2007
IN VIVO INDUCTION OF HUMAN CYTOCHROME P450 ENZYMES EXPRESSED IN CHIMERIC MICE WITH HUMANIZED LIVER
2005
Hepatic polyploidy and liver growth control
2000
Molecular biology of hepatitis B virus infection
2015
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Pluripotent stem cell-derived hepatocyte-like cells
2014
Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
2010
Asthma
2001 Standout
Attacking hepatitis B virus cccDNA – The holy grail to hepatitis B cure
2016
Optimal management of hepatitis B virus infection – EASL Special Conference
2015
Chimeric mice with humanized liver
2007
A simple and rapid method to determine the zygosity of uPA-transgenic SCID mice
2003
The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional
2011
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection
2013
Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice
2008
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Sarcoidosis
1997 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Hepatitis B virus infection
2018
Hepatitis C Virus Entry
2007 StandoutNobel
Sustained survival of human hepatocytes in mice: A model for in vivo infection with human hepatitis B and hepatitis delta viruses
2000
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
2015
A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production
2019
Extensive double humanization of both liver and hematopoiesis in FRGN mice
2014
Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe
2006
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
The role of innate immunity in the immunopathology and treatment of HBV infection
2016
Late HDV RNA Relapse After Peginterferon Alpha-Based Therapy of Chronic Hepatitis Delta
2014
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Quantification of HBsAg in nucleos(t)ide-naïve patients treated for chronic hepatitis B with entecavir with or without tenofovir in the BE-LOW study
2014
Assessment of Bone Mineral Density in Tenofovir-Treated Patients With Chronic Hepatitis B: Can the Fracture Risk Assessment Tool Identify Those at Greatest Risk?
2014
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Review article: chronic hepatitis B – anti‐viral or immunomodulatory therapy?
2010
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA
2015 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Replicative Activity of Hepatitis B Virus Is Negatively Associated with Methylation of Covalently Closed Circular DNA in Advanced Hepatitis B Virus Infection
2011
Sarcoidosis
2007 Standout
Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice
2010
Morphological and biochemical characterization of a human liver in a uPA‐SCID mouse chimera†‡
2005
Risk of hepatocellular carcinoma in chronic hepatitis B: Assessment and modification with current antiviral therapy
2015
Hepatitis B core-related antigen (HBcrAg) levels in the natural history of hepatitis B virus infection in a large European cohort predominantly infected with genotypes A and D
2015
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
2008
Effect of Virological Response to Entecavir on the Development of Hepatocellular Carcinoma in Hepatitis B Viral Cirrhotic Patients: Comparison Between Compensated and Decompensated Cirrhosis
2014
Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection
2013
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes
2013
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells
2016 StandoutNobel
Effectiveness and Safety of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B: A 3-Year Prospective Field Practice Study in Germany
2015
Influence of hepatitis B virus genotypes on the intra‐ and extracellular expression of viral DNA and antigens†‡
2006
Replication of hepatitis C virus
2007 StandoutNobel
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Infliximab Therapy in Patients with Chronic Sarcoidosis and Pulmonary Involvement
2006
Nucleoside/nucleotide analogues in the treatment of chronic hepatitis B
2011
Hepatocellular Carcinoma
2019 Standout
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
2017 Standout
Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)
2014
AASLD guidelines for treatment of chronic hepatitis B
2015
Replication of hepatitis C virus
2000
Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections
2010
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
New Insights into how HBV Manipulates the Innate Immune Response to Establish Acute and Persistent Infection
2013
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Hepatitis B virus core‐related antigen as a surrogate marker for covalently closed circular DNA
2016
Review article: the potential of interferon and nucleos(t)ide analogue combination therapy in chronic hepatitis B infection
2016
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Antiviral treatment and liver‐related complications in hepatitis delta
2016
NTCP and Beyond: Opening the Door to Unveil Hepatitis B Virus Entry
2014
Artificial Molecular Machines
2015 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Serum HBV core‐related antigen is a good predictor for spontaneous HBeAg seroconversion in chronic hepatitis B patients
2016
Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model
2007
Poly(ADP-ribose) (PAR) polymer is a death signal
2006 Standout
Pre-S1 Antigen-Dependent Infection of Tupaia Hepatocyte Cultures with Human Hepatitis B Virus
2003
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Review article: long‐term safety of nucleoside and nucleotide analogues in HBV ‐monoinfected patients
2016
Entecavir safety and effectiveness in a national cohort of treatment‐naïve chronic hepatitis B patients in the US – the ENUMERATE study
2015
Global cancer statistics, 2012
2015 Standout
Towards a small animal model for hepatitis C
2009 StandoutNobel
Inhibitory Effect of Adefovir on Viral DNA Synthesis and Covalently Closed Circular DNA Formation in Duck Hepatitis B Virus-Infected Hepatocytes In Vivo and In Vitro
2002
Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: An international multicenter cohort study
2011
New Therapeutic Targets and Drugs for the Treatment of Chronic Hepatitis B
2013
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Works of Joerg Petersen being referenced
Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes
2004
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
2014
Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation
2002
The replication cycle of hepatitis B virus
2009
Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir In vitro do not lead to reduction of the closed circular DNA
2000
Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients
2007
Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
2013
Seven-Year Efficacy and Safety of Treatment with Tenofovir Disoproxil Fumarate for Chronic Hepatitis B Virus Infection
2014
Repopulation of Mouse Liver With Human Hepatocytes And In Vivo Infection With Hepatitis B Virus
2001
In Vivo Proliferation of Hepadnavirus-Infected Hepatocytes Induces Loss of Covalently Closed Circular DNA in Mice
2010
Hepatitis B Virus Limits Response of Human Hepatocytes to Interferon-α in Chimeric Mice
2011
IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome
2012
Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B
2006
Increased secretion of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 by alveolar macrophages from patients with sarcoidosis
1993
Liver repopulation with xenogenic hepatocytes in B and T cell-deficient mice leads to chronic hepadnavirus infection and clonal growth of hepatocellular carcinoma
1998
Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis
2012
Sequential Combination Therapy Leads to Biochemical and Histological Improvement Despite Low Ongoing Intrahepatic Hepatitis B virus Replication
2008