Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone
1997
The protein import motor of mitochondria
2002
Calnexin Discriminates between Protein Conformational States and Functions as a Molecular Chaperone In Vitro
1999
Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site
1991 StandoutNobel
mei-1, a gene required for meiotic spindle formation in Caenorhabditis elegans, is a member of a family of ATPases.
1994
Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries
1997
Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation
2015 Nature
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
The power stroke of the DnaK/DnaJ/GrpE molecular chaperone system 1 1Edited by J.Karn
1997
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue
1997 Nature
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
Effective approach for calculations of absolute stability of proteins using focused dielectric constants
2009 StandoutNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1
1997
Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles
2014
Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps
2019
Structure of a GDP:AlF4 Complex of the SRP GTPases Ffh and FtsY, and Identification of a Peripheral Nucleotide Interaction Site
2006
Dynamics connect substrate recognition to catalysis in protein kinase A
2010
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Protein Translocation
1999 StandoutNobel
L23 protein functions as a chaperone docking site on the ribosome
2002 Nature
Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle
2013
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation
1989 Nature
Exploring Global Distortions of Biological Macromolecules and Assemblies from Low-resolution Structural Information and Elastic Network Theory
2002
The Hsp70 and Hsp60 Chaperone Machines
1998 Standout
Electrostatic control of GTP and GDP binding in the oncoprotein p21ras
1996 StandoutNobel
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1994 StandoutNobel
Flavin‐based Blue‐light Photosensors: A Photobiophysics Update
2007
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae
1997
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
O-GlcNAc cycling: Implications for neurodegenerative disorders
2009
Time-Resolved Small-Angle X-ray Scattering Study of the Folding Dynamics of Barnase
2010
Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor Ap5A refined at 1.9 Å resolution
1992
Intrinsic motions along an enzymatic reaction trajectory
2007 Nature
Role of Glutamine-61 in the Hydrolysis of GTP by p21H-ras: An Experimental and Theoretical Study
1994
Hsp70 chaperones: Cellular functions and molecular mechanism
2005 Standout
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
1995 StandoutNobel
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine
2009
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
A transposase strategy for creating libraries of circularly permuted proteins
2012
Molecular Basis for the Unique Role of the AAA+ Chaperone ClpV in Type VI Protein Secretion
2011
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Lessons in stability from thermophilic proteins
2006
Recruitment of Hsp70 chaperones: a crucial part of viral survival strategies
2004
Protein structure homology modeling using SWISS-MODEL workspace
2008
Chaperones get in touch: the Hip-Hop connection
1997
The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism
2000
Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp
1999 StandoutNatureNobel
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
Enzyme catalysis: not different, just better
1991 Nature
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination
1990
The P-loop — a common motif in ATP- and GTP-binding proteins
1990 Standout
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Not all J domains are created equal: Implications for the specificity of Hsp40–Hsp70 interactions
2005
The ESCRT Pathway
2011
Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells
2000
The HSP70 chaperone machinery: J proteins as drivers of functional specificity
2010
Role of mitochondrial GrpE and phosphate in the ATPase cycle of matrix Hsp70
1997
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins
1999
Redox Control of Protein Conformation in Flavoproteins
2009
Folding of Conotoxins: Formation of the Native Disulfide Bridges During Chemical Synthesis and Biosynthesis of Conus Peptides
2007
A cycle of binding and release of the DnaK, DnaJ and GrpE chaperones regulates activity of the Escherichia coli heat shock transcription factor sigma32.
1996
The Kinetics of Helix Unfolding of an Azobenzene Cross-Linked Peptide Probed by Nanosecond Time-Resolved Optical Rotatory Dispersion
2003
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Single-Molecule Fluorescence Studies of Protein Folding and Conformational Dynamics
2006
Linkage between dynamics and catalysis in a thermophilic-mesophilic enzyme pair
2004
Mechanism of GTP hydrolysis by G-protein alpha subunits.
1994 StandoutNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
DnaJ Dramatically Stimulates ATP Hydrolysis by DnaK: Insight into Targeting of Hsp70 Proteins to Polypeptide Substrates
1999
Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).
1994
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
The Cation−π Interaction
1997 Standout
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular Permutation
2016
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication
2016 StandoutNobel
Reaction mechanism of Drosophila cryptochrome
2010 StandoutNobel
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
The human cytosolic molecular chaperones hsp90, hsp70 (hsc70) and hdj-1 have distinct roles in recognition of a non-native protein and protein refolding.
1996
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy
2003 StandoutNobel
Functional Studies on the Candidate ATPase Domains of Saccharomyces cerevisiae MutLα
2000
Interaction of Hsp70 chaperones with substrates
1997
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones
2001
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
2011 StandoutScienceNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Structural Analysis of Substrate Binding by the Molecular Chaperone DnaK
1996 Science
Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities.
1991
A New Approach to Producing Functional Gα Subunits Yields the Activated and Deactivated Structures of Gα12/13 Proteins
2005
NMR structure of the calreticulin P-domain
2001 StandoutNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase
2010 StandoutNobel
Works of Jochen Reinstein being referenced
ATP-binding Properties of Human Hsp90
1997
Coupling and Dynamics of Subunits in the Hexameric AAA+ Chaperone ClpB
2008
Mutations in the nucleotide binding loop of adenylate kinase of Escherichia coli
1988
Complexes of Escherichia coli adenylate kinase and nucleotides: proton NMR studies of the nucleotide sites in solution
1990
Crystal Structures of the AppA BLUF Domain Photoreceptor Provide Insights into Blue Light-mediated Signal Transduction
2006
The Role of ATP in the Functional Cycle of the DnaK Chaperone System
1995
Modulation of the ATPase Cycle of BiP by Peptides and Proteins
2003
The Influence of Proline Isomerization and Off-Pathway Intermediates on the Folding Mechanism of Eukaryotic UMP/CMP Kinase
2008
Nucleotide-induced Conformational Changes in the ATPase and Substrate Binding Domains of the DnaK Chaperone Provide Evidence for Interdomain Communication
1995
pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog.
1999
Dissection of the Contribution of Individual Domains to the ATPase Mechanism of Hsp90
2003
Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ
2013
Ataxin-10 Interacts with O-Linked β-N-Acetylglucosamine Transferase in the Brain
2006
Structurally and catalytically important residues in the phosphate binding loop of adenylate kinase of Escherichia coli
1990
Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.
2001
Disaggregases in 4 dimensions
2010
Sti1 Is a Novel Activator of the Ssa Proteins
2003
The Second Step of ATP Binding to DnaK Induces Peptide Release
1996
Adenylate kinases from thermosensitive Escherichia coli strains
1989
p21 with a phenylalanine 28—-leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties.
1991
Crystal Structure of the Complex of UMP/CMP Kinase from Dictyostelium discoideum and the Bisubstrate Inhibitor P1-(5‘-Adenosyl) P5-(5‘-Uridyl) Pentaphosphate (UP5A) and Mg2+ at 2.2 Å: Implications for Water-Mediated Specificity
1996
Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding
1996
Structural and catalytic role of arginine 88 in Escherichia coli adenylate kinase as evidenced by chemical modification and site-directed mutagenesis
1989
Assessment of the ATP Binding Properties of Hsp90
1996
Mechanism of regulation of Hsp70 chaperones by DnaJ cochaperones
1999
GrpE Accelerates Nucleotide Exchange of the Molecular Chaperone DnaK with an Associative Displacement Mechanism
1997
Structures of Active Conformations of UMP Kinase from Dictyostelium discoideum Suggest Phosphoryl Transfer Is Associative
1997
Microsecond Folding of the Cold Shock Protein Measured by a Pressure-Jump Technique
1999