Citation Impact
Citing Papers
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration
2005 StandoutScience
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Complement Factor H Polymorphism in Age-Related Macular Degeneration
2005 StandoutScience
Structure and Function of the Complement Receptors, CR1 (CD35) and CR2 (CD21)
1989
Direct Evidence that Saquinavir Is Transported by Multidrug Resistance-Associated Protein (MRP1) and Canalicular Multispecific Organic Anion Transporter (MRP2)
2002
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity
1996 Standout
Saint John's wort: An in vitro analysis of P‐glycoprotein induction due to extended exposure
2001
Modulation of P‐glycoprotein‐mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane
2007
Host recognition and target differentiation by factor H, a regulator of the alternative pathway of complement
2000
The influence of lipophilicity in drug discovery and design
2012
Two Mosquito LRR Proteins Function as Complement Control Factors in the TEP1-Mediated Killing of Plasmodium
2009 StandoutNobel
Pathways for bradykinin formation and inflammatory disease
2002
Cancer Statistics, 2006
2006 Standout
Liposome—complement interactions in rat serum: implications for liposome survival studies
1994
Inflammatory bowel disease: clinical aspects and established and evolving therapies
2007 Standout
C1: molecular interactions with activating systems
1991
IgE and mast cells in allergic disease
2012 Standout
Towards Dynamic Control of Wettability by Using Functionalized Altitudinal Molecular Motors on Solid Surfaces
2013 StandoutNobel
Regulation of Alternative Pathway Activation and C3a Production by Adipose Cells
1996
Complement system proteins which interact with C3b or C4b A superfamily of structurally related proteins
1986
Complement: a key system for immune surveillance and homeostasis
2010 Standout
Age-related macular degeneration
2012 Standout
Minimizing the immunogenicity of protein therapeutics
2004
Glycans in cancer and inflammation — potential for therapeutics and diagnostics
2005 StandoutNobel
All ras proteins are polyisoprenylated but only some are palmitoylated
1989 Standout
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
2007 Standout
Targeting multidrug resistance in cancer
2006 Standout
Prediction of intestinal permeability
2002
Discrimination between host and pathogens by the complement system
2008
Preclinical safety evaluation of biotechnology-derived pharmaceuticals
2002
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
2015 Standout
Complement resistance of tumor cells: basal and induced mechanisms
1999
What is modulating solubility in simulated intestinal fluids?
2010
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Polyphenols: food sources and bioavailability
2004 Standout
HIV and human complement: mechanisms of interaction and biological implication
1993
Structure of complement fragment C3b–factor H and implications for host protection by complement regulators
2009
Molecular pathology of age-related macular degeneration
2008
C1 Inhibitor-C 1 ¯ s
1997
Complement
2001 Standout
An Industry Perspective on the Monitoring of Subvisible Particles as a Quality Attribute for Protein Therapeutics
2010
Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells
2009
Pharmacokinetic and Pharmacodynamic Implications of P‐glycoprotein Modulation
2001
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Points of control in inflammation
2002 StandoutNature
Liposomal drug delivery systems: From concept to clinical applications
2012 Standout
The internal thioester and the covalent binding properties of the complement proteins C3 and C4
1997
Relevance of Multidrug Resistance Proteins for Intestinal Drug Absorption in vitro and in vivo
2002
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Interferon β-1a in ulcerative colitis: a placebo controlled, randomised, dose escalating study
2003
Immunogenicity of protein therapeutics
2007
The human IgE network
1993 Nature
Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT)
2004
Functional Expression and Localization of P-glycoprotein in the Central Nervous System: Relevance to the Pathogenesis and Treatment of Neurological Disorders
2004
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
The dawning era of polymer therapeutics
2003 Standout
Complement-related proteins in pathogenic organisms
1994
Nanoparticles of poly(lactide)—tocopheryl polyethylene glycol succinate (PLA-TPGS) copolymers for protein drug delivery
2007
Complement driven by conformational changes
2007
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
2006 Standout
Cell Biology of the Glomerular Podocyte
2003 Standout
Localization of the heparin-binding site on complement factor H.
1991
The complement binding-like domains of the murine homing receptor facilitate lectin activity.
1991
Organic synthesis reactions on-water at the organic–liquid water interface
2016
Serpin Structure, Mechanism, and Function
2002 Standout
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
2001 Standout
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
Prediction of Drug Absorption Using Multivariate Statistics
2000 Standout
Sea urchin coelomocytes specifically express a homologue of the complement component C3.
1998
Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles
2011 Standout
Superresolution Imaging of Targeted Proteins in Fixed and Living Cells Using Photoactivatable Organic Fluorophores
2010 StandoutNobel
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
2009 StandoutScience
Advances in biomaterials, drug delivery, and bionanotechnology
2003
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Design of therapeutic proteins with enhanced stability
2009
Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression
1994 StandoutNobel
Leukocyte-endothelial adhesion molecules
1994 Standout
Understanding Adipocyte Differentiation
1998 Standout
Control of the Complement System
1996
The phylogeny and evolution of the thioester bond‐containing proteins C3, C4 and α2–macroglobulin
1998
The human complement factor H: functional roles, genetic variations and disease associations
2004
Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins
1989 StandoutScience
Generation of a Set of Simple, Interpretable ADMET Rules of Thumb
2008
De novo design of small beta barrel proteins
2023 StandoutNobel
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Individual epitopes of an 85,000 MW membrane adherence molecule are variably expressed on cells of different lineage.
1988
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
2009 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Sea Urchin Coelomocytes Specifically Express a Homologue of the Complement Component C3
1998
Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1
2011
Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants ofDrosophila
2000 StandoutNobel
Markedly Different Pathogenicity of Four Immunoglobulin G Isotype-Switch Variants of an Antierythrocyte Autoantibody Is Based on Their Capacity to Interact in Vivo with the Low-Affinity Fcγ Receptor III
2000 StandoutNobel
Chemistry Takes a Bath: Reactions in Aqueous Media
2018 StandoutNobel
Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.
1987
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy
2005
Works of Jochem Alsenz being referenced
Oral Absorption of Peptides Through the Cobalamin (Vitamin B12) Pathway in the Rat Intestine
2000
Third component of trout complement. cDNA cloning and conservation of functional sites.
1993
The Role of Surfactants in the Reversal of Active Transport Mediated by Multidrug Resistance Proteins
2003
Acquired C1 inhibitor (C1-INH) deficiency type II. Replacement therapy with C1-INH and analysis of patients' C1-INH and anti-C1-INH autoantibodies.
1989
Active Apical Secretory Efflux of the HIV Protease Inhibitors Saquinavir and Ritonavir in Caco-2 Cell Monolayers
1998
Evidence for multiple sites of interaction in C3 for complement receptor type 2 (C3d/EBV receptor, CD21)
1991
Structural and Functional Analysis of C3 Using Monoclonal Antibodies
1990
Molecular Aspects of C3 Interactions and Structural/Functional Analysis of C3 from Different Species
1990
Protein Aggregates Seem to Play a Key Role Among the Parameters Influencing the Antigenicity of Interferon Alpha (IFN-α) in Normal and Transgenic Mice
1997
High throughput solubility measurement in drug discovery and development
2007
P-glycoprotein and surfactants: Effect on intestinal talinolol absorption
2005
Cell Surface Proteins Reacting with Activated Complement Components
1989
Development of a 7-Day, 96-Well Caco-2 Permeability Assay with High-Throughput Direct UV Compound Analysis
2003
Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B
1992
Role of C3b receptors in the enhancement of interleukin-2-dependent T-cell proliferation
1984
Use of monoclonal antibodies against factor H to investigate the role of a membrane-associated protein antigenically related to H in C3b-receptor function.
1984
Structural and functional analysis of the complement component factor H with the use of different enzymes and monoclonal antibodies to factor H
1985
Estimation of permeability by passive diffusion through Caco-2 cell monolayers using the drugs' lipophilicity and molecular weight
1998
Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38kDa tryptic fragment of factor H
1984
Simplified methods for the purification, quantitation, and functional estimation of human complement C-inhibitor (C-INH) with a monoclonal anti-C-INH antibody
1987
Autoantibody-Mediated Acquired Deficiency of C1 Inhibitor
1987
Interferon immunogenicity: preclinical evaluation of interferon-alpha 2a.
1997