Citation Impact
Citing Papers
Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGFβ-Activating miR424–503 Gene Cluster
2014
The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis
2012
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis
2009
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Hepatic triacylglycerol accumulation and insulin resistance
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Starvation Induced Cell Death in Autophagy-Defective Yeast Mutants Is Caused by Mitochondria Dysfunction
2011 StandoutNobel
Cancer to bone: a fatal attraction
2011 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Heterozygous HIF‐1α deficiency impairs carotid body‐mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
2006 StandoutNobel
Hypoxia and Inflammation
2011 Standout
Surviving at a Distance: Organ-Specific Metastasis
2015
A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics
2016 StandoutNobel
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Canonical and Noncanonical Hedgehog/GLI Signaling in Hematological Malignancies
2012
Roles of TGFβ in metastasis
2008
FOSL2 promotes leptin gene expression in human and mouse adipocytes
2012
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Cytokine patterns in patients with cancer: a systematic review
2013 Standout
Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
2009
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
2009 Standout
Emerging role of adipose tissue hypoxia in obesity and insulin resistance
2008
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Review article: Is obesity an inflammatory illness? Role of low‐grade inflammation and macrophage infiltration in human white adipose tissue
2006
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
Emerging Biological Principles of Metastasis
2017 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
2008 Standout
TGFβ in Cancer
2008 Standout
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
2011 StandoutNobel
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
2010
A potential link between muscle peroxisome proliferator- activated receptor-α signaling and obesity-related diabetes
2005
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation
2009
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Signaling cross-talk between TGF-β/BMP and other pathways
2008
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration
2007
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice
2011
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency
2005
Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle
2012
Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
2004
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
The Hedgehog System Machinery Controls Transforming Growth Factor-β–Dependent Myofibroblastic Differentiation in Humans
2012
Oxygen homeostasis
2009 StandoutNobel
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice
2002
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Integration of Oxygen Signaling at the Consensus HRE
2005
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
2009
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Obesity-Related Derangements in Metabolic Regulation
2006
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
2012
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Targeting Hedgehog — a Cancer Stem Cell Pathway
2010
Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
2013
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice
2002
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
2007 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Regulation of angiogenesis by hypoxia-inducible factor 1
2006 StandoutNobel
Works of Jocelyne André being referenced
Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis
2007
Cloning of the Human GLI2 Promoter
2009
ERK and PDE4 cooperate to induce RAF isoform switching in melanoma
2011
Hypoxia-inducible Factor 1 Transactivates the Human Leptin Gene Promoter
2002
Transcriptional effect of hypoxia on placental leptin
2001
Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo
2005
PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance
2001
Induction of Sonic Hedgehog Mediators by Transforming Growth Factor-β: Smad3-Dependent Activation of Gli2 and Gli1 Expression In vitro and In vivo
2007