Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Evolution of the Cancer Stem Cell Model
2014 Standout
Cancer statistics, 2023
2023 Standout
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
2010
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
Cancer statistics, 2024
2024 Standout
Benefits and limitations of genome-wide association studies
2019
The molecular hallmarks of epigenetic control
2016 Standout
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
2011
Sexual dimorphism in cancer
2016
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
Evolution of the cancer genome
2012
Epigenetics and the environment: emerging patterns and implications
2012 Standout
Evidence that Prefibrotic Myelofibrosis Is Aligned along a Clinical and Biological Continuum Featuring Primary Myelofibrosis
2012
Regulation of chromatin by histone modifications
2011 Standout
Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry
2014
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
2017
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
The emerging role of lncRNAs in cancer
2015 Standout
Histone methylation: a dynamic mark in health, disease and inheritance
2012 Standout
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
2013
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations
2013
Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias
2016
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
DNA methylation: roles in mammalian development
2013 Standout
Current and future perspectives of liquid biopsies in genomics-driven oncology
2018 Standout
PRC2 mediated H3K27 methylations in cellular identity and cancer
2015
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates
2013
The hypoxic tumor microenvironment: A driving force for breast cancer progression
2015 StandoutNobel
Recruitment of healthy mitochondria fuels transmissible cancers
2011
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer
2016
Lack of microRNA‐101 causes E‐cadherin functional deregulation through EZH2 up‐regulation in intestinal gastric cancer
2012
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Immunopathology of multiple sclerosis
2015 Standout
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
Investigational Janus kinase inhibitors
2013
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
2010
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
2013 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
Driver mutations of cancer epigenomes
2014
Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
2018 StandoutNobel
Histone Methyltransferase EZH2 Is Transcriptionally Induced by Estradiol as Well as Estrogenic Endocrine Disruptors Bisphenol-A and Diethylstilbestrol
2014
Epigenetic factors influencing resistance to nuclear reprogramming
2011 StandoutNobel
Clonal evolution in cancer
2012 StandoutNature
Developmental Control of Polycomb Subunit Composition by GATA Factors Mediates a Switch to Non-Canonical Functions
2015
Cancer-related inflammation and treatment effectiveness
2014 Standout
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Mitochondria and cancer
2012 Standout
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia
2012
EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas
2011
The future of epigenetic therapy in solid tumours—lessons from the past
2013
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase
2017 StandoutNobel
Recent developments in myelodysplastic syndromes
2014
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
2011
Acute Myeloid Leukemia
2015 Standout
Long Noncoding RNA and Cancer: A New Paradigm
2017 Standout
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
2014 Standout
EZH2 Mutations: Mutating the Epigenetic Machinery in Myeloid Malignancies
2010
Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
2012
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
2012
Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia
2013
Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes
2013
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations
2016 Standout
RUNX1Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group
2011
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Cancer stem cells as ‘units of selection’
2012
Sex disparities in the incidence of 21 cancer types: Quantification of the contribution of risk factors
2022
Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment
2011
Genomics of chronic neutrophilic leukemia
2016
Prognostic Significance ofASXL1Mutations in Patients With Myelodysplastic Syndromes
2011
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
Liquid Biopsies: Genotyping Circulating Tumor DNA
2014 Standout
TET2 Mutations in Acute Myeloid Leukemia (AML): Results From a Comprehensive Genetic and Clinical Analysis of the AML Study Group
2012
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
2014
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
2015 Science
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Works of Joannah Score being referenced
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
2010
Acquired Uniparental Disomy in Myeloproliferative Neoplasms
2012
Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer
2014
Immunologically silent cancer clone transmission from mother to offspring
2009
In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinib
2010
Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms
2011
Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms
2009
EZH2 mutational status predicts poor survival in myelofibrosis
2011