Citation Impact
Citing Papers
Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
2005 StandoutScience
Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors
2009
Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury
2010
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O2 levels
2003 StandoutNobel
Increased Prolyl 4-Hydroxylase Domain Proteins Compensate for Decreased Oxygen Levels
2006
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
2010
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Progressive Increase of T1 Signal Intensity of the Dentate Nucleus on Unenhanced Magnetic Resonance Images Is Associated With Cumulative Doses of Intravenously Administered Gadodiamide in Patients With Normal Renal Function, Suggesting Dechelation
2014
The von Hippel Lindau/Hypoxia-inducible Factor (HIF) Pathway Regulates the Transcription of the HIF-Proline Hydroxylase Genes in Response to Low Oxygen
2003
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival
2011
The Failing Heart — An Engine Out of Fuel
2007 Standout
Protective effects of ranolazine in guinea‐pig hearts during low‐flow ischaemia and their association with increases in active pyruvate dehydrogenase
1993
Gadolinium Retention: A Research Roadmap from the 2018 NIH/ACR/RSNA Workshop on Gadolinium Chelates
2018
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure
2002
Characterization of the First Potent and Selective PDE9 Inhibitor Using a cGMP Reporter Cell Line
2005
Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia
2010
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Cyclosporin A Prevents the Hypoxic Adaptation by Activating Hypoxia-inducible Factor-1α Pro-564 Hydroxylation
2003
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Erectile Dysfunction and Lower Urinary Tract
2008
EGLN3 Prolyl Hydroxylase Regulates Skeletal Muscle Differentiation and Myogenin Protein Stability
2007
Energy Metabolism in the Normal and Failing Heart: Potential for Therapeutic Interventions
2002
Defining the Role for XAP2 in Stabilization of the Dioxin Receptor
2003
Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor
2003
An Endoplasmic Reticulum Transmembrane Prolyl 4-Hydroxylase Is Induced by Hypoxia and Acts on Hypoxia-inducible Factor α
2007
The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor α
2004 StandoutNobel
Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging
2015
Mitochondrial function in the oxygen depleted and reoxygenated myocardial cell
1994
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
2004 StandoutNobel
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Proton conductance caused by long-chain fatty acids in phospholipid bilayer membranes
1988
Ranolazine Increases Active Pyruvate Dehydrogenase in Perfused Normoxic Rat Hearts: Evidence for an Indirect Mechanism
1996
Mitochondrial Dysfunction in Cardiac Disease: Ischemia–Reperfusion, Aging, and Heart Failure
2001
The use of ranolazine in cardiovascular disease
2002
High Signal Intensity in Dentate Nucleus on Unenhanced T1-weighted MR Images: Association with Linear versus Macrocyclic Gadolinium Chelate Administration
2015
Biodistribution of gadolinium‐based contrast agents, including gadolinium deposition
2009
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes
2004 StandoutNobel
Atomic structure and chemistry of human serum albumin
1992 StandoutNature
The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin
2004 StandoutNobel
Crystal Structure of the Non-heme Iron Dioxygenase PtlH in Pentalenolactone Biosynthesis
2007 StandoutNobel
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1 in normoxia
2003 Standout
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation
2006 StandoutNobel
Ranolazine: A Novel Metabolic Modulator for the Treatment of Angina
1998
The Use of Partial Fatty Acid Oxidation Inhibitors for Metabolic Therapy of Angina Pectoris and Heart Failure
2002
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Fe(II)/α-Ketoglutarate-Dependent Hydroxylases and Related Enzymes
2004
Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation
2007
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Molecular mechanisms that could contribute to prolonged effectiveness of PDE5 inhibitors to improve erectile function
2008
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Regulation of fatty acid oxidation in the mammalian heart in health and disease
1994
Caveolin, a protein component of caveolae membrane coats
1992 Standout
Therapeutic Manipulation of the HIF Hydroxylases
2009
Cyclic GMP-Hydrolyzing Phosphodiesterases
2008
Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation
2006 StandoutNobel
Life with Oxygen
2007 StandoutScienceNobel
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Integration of Oxygen Signaling at the Consensus HRE
2005
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Activation of the hypoxia‐inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
2003
Functional rafts in cell membranes
1997 StandoutNature
Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element
2005
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein.
1988 Nobel
Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles
2004 StandoutNobel
Coordinate Regulation of the Oxygen-Dependent Degradation Domains of Hypoxia-Inducible Factor 1α
2005
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
The HIF Pathway and Erythrocytosis
2011
Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis
2012
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Protective Effects of Ranolazine on Ventricular Fibrillation Induced by Activation of the ATP-Dependent Potassium Channel in the Rabbit Heart
1996
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
Caveolae: Static inpocketings of the plasma membrane, dynamic vesicles or plain artifact?
1988
Metabolic Modulators for Chronic Cardiac Ischemia
2005
Vardenafil Improves Urodynamic Parameters in Men With Spinal Cord Injury: Results From a Single Dose, Pilot Study
2007
Expression of prolyl-hydroxylase-1 (PHD1/EGLN2) suppresses hypoxia inducible factor-1alpha activation and inhibits tumor growth.
2003
Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases
2003
Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis.
1986
Intracellular localisation of human HIF-1α hydroxylases:implications for oxygen sensing
2003
Pharmacological Activation of Soluble Guanylate Cyclase Protects the Heart Against Ischemic Injury
2009
Myocardial triglyceride turnover during reperfusion of isolated rat hearts subjected to a transient period of global ischemia.
1992
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors
2004
Metal–Organic Frameworks in Biomedicine
2011 Standout
Exceedingly small iron oxide nanoparticles as positive MRI contrast agents
2017 StandoutNobel
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
NO-Independent, Haem-Dependent Soluble Guanylate Cyclase Stimulators
2008
The ATP/ADP‐antiporter is involved in the uncoupling effect of fatty acids on mitochondria
1989
Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers
2018
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Ranolazine Stimulates Glucose Oxidation in Normoxic, Ischemic, and Reperfused Ischemic Rat Hearts
1996
Works of Joachim Hütter being referenced
The Role of Residual Gadolinium in the Induction of Nephrogenic Systemic Fibrosis-Like Skin Lesions in Rats
2010
Impact of Renal Impairment on Long-Term Retention of Gadolinium in the Rodent Skin Following the Administration of Gadolinium-Based Contrast Agents
2009
Stability of Gadolinium-Based Magnetic Resonance Imaging Contrast Agents in Human Serum at 37°C
2008
Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors
2002
Pre‐clinical evidence for the use of phosphodiesterase‐5 inhibitors for treating benign prostatic hyperplasia and lower urinary tract symptoms
2006
Effect of recombinant aprotinin on postoperative blood loss and coronary vascular function in a canine model of cardiopulmonary bypass
2007
Long-term retention of gadolinium in the skin of rodents following the administration of gadolinium-based contrast agents
2009
A cell-based cGMP assay useful for ultra-high-throughput screening and identification of modulators of the nitric oxide/cGMP pathway
2005
Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT2) receptor
2010
PDE5 inhibitors beyond erectile dysfunction
2007
Fatty acid-membrane interactions in isolated cardiac mitochondria and erythrocytes
1983
Effect of fatty acid oxidation on efficiency of energy production in rat heart
1985
Inhibition of fatty acid oxidation and decrease of oxygen consumption of working rat heart by 4-bromocrotonic acid
1984
Development of ischemia-induced damage in defined mitochondrial subpopulations
1985
Kinetic analysis of myocardial fatty acid oxidation suggesting an albumin receptor mediated uptake process*
1984
Early enzyme release from myocardial cells is not due to irreversible cell damage*
1984
Myocardial fatty acid oxidation: Evidence for an albumin-receptor-mediated membrane transfer of fatty acids
1984
Acyl-carnitine effects on isolated cardiac mitochondria and erythrocytes
1984