Citation Impact
Citing Papers
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing
1985 StandoutNatureNobel
By-passing immunization
1991 StandoutNobel
The Escherichia coli SRP and SecB targeting pathways converge at the translocon
1998
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
RNA-RNA interactions in the spliceosome: Unraveling the ties that bind
1994
Ribozyme-catalysed amino-acid transfer reactions
1996 StandoutNatureNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
The signal recognition particle in S. cerevisiae
1991
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
Functional proteins from a random-sequence library
2001 StandoutNatureNobel
Evolutionary conserved nucleotides within theE.coli4.5S RNA are required for association with P48in vitroand for optimal functionin vivo
1992
Two conserved domains of yeast U2 snRNA are separated by 945 nonessential nucleotides
1988
The guanosine binding site of the Tetrahymena ribozyme
1989 StandoutNatureNobel
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
Translocation of proteins across the endoplasmic reticulum
1993
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
RNA-catalysed synthesis of complementary-strand RNA
1989 StandoutNatureNobel
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex
1991 StandoutNatureNobel
Structure of the E. coli protein-conducting channel bound to a translating ribosome
2005 StandoutNatureNobel
SR proteins can compensate for the loss of U1 snRNP functions in vitro.
1994
Human SRP RNA and E. coli 4.5S RNA contain a highly homologous structural domain
1988
An experimental study ofSaccharomyces cerevisiaeU3 snRNA conformation in solution
1992
Alteration of the RNA polymerase specificity of U3 snRNA genes during evolution and in vitro
1991
Empty Site Forms of the SRP54 and SRα GTPases Mediate Targeting of Ribosome–Nascent Chain Complexes to the Endoplasmic Reticulum
1997
Characterization of the U3 and U6 snRNA genes from wheat: U3 snRNA genes in monocot plants are transcribed by RNa polymerase III
1992
In vitro evolution of new ribozymes with polynucleotide kinase activity
1994 StandoutNatureNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1989 StandoutNatureNobel
Signal recognition particle-depencent protein targeting, universal to all kingdoms of life
2002
Saccharomyces cerevisiae Has a U1-Like Small Nuclear RNA with Unexpected Properties
1987 Science
The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction
1985 Science
Stereochemistry of RNA Cleavage by the Tetrahymena Ribozyme and Evidence that the Chemical Step Is Not Rate-Limiting
1989 StandoutScienceNobel
Isolation of S. cerevisiae snRNPs: comparison of U1 and U4/U6.U5 to Their Human Counterparts
1994 Science
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs
1986
PRE-mRNA SPLICING
1986
Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY
2001
Transabdominal, a dominant mutant of the Bithorax Complex, produces a sexually dimorphic segmental transformation in Drosophila.
1987 StandoutNobel
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing
1987 Nature
Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction
1983 StandoutNatureNobel
Coupling of Tetrahymena Ribosomal RNA Splicing to β-Galactosidase Expression in Escherichia coli
1985 StandoutScienceNobel
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.
1991
Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.
1986
cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments.
1985
Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA
1987
Two major tertiary folding transitions of the Tetrahymena catalytic RNA.
1994 Nobel
Lariat structures are in vivo intermediates in yeast pre-mRNA splicing
1984
The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain.
1990
Initiation by Yeast RNA Polymerase II at the Adenoviral Major Late Promoter in Vitro
1989 StandoutScienceNobel
Sequence of U1 RNA from Drosophila melanogaster: implications for U1 secondary structure and possible involvement in splicing
1981
S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA
1987 StandoutNobel
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Yeast mRNA splicing in vitro.
1985
The Intervening Sequence RNA of Tetrahymena Is an Enzyme
1986 StandoutScienceNobel
Randomization of genes by PCR mutagenesis.
1992
5' splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements.
1988
Are U4 small nuclear ribonucleoproteins involved in polyadenylation?
1984 Nature
A Labile Phosphodiester Bond at the Ligation Junction in a Circular Intervening Sequence RNA
1984 StandoutScienceNobel
Functional Mapping of the U3 Small Nucleolar RNA from the Yeast Saccharomyces cerevisiae
1998
The Signal Recognition Particle
2001
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA
1984 StandoutNatureNobel
Cloning and characterization of PSF, a novel pre-mRNA splicing factor.
1993
In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
1981 StandoutNobel
Efficient Trans-Splicing of a Yeast Mitochondrial RNA Group II Intron Implicates a Strong 5′ Exon-Intron Interaction
1986 StandoutScienceNobel
Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins
1999
Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.
1989 StandoutNobel
A point mutation in the conserved hexanucleotide at a yeast 5′ splice junction uncouples recognition, cleavage, and ligation
1985
A novel role for the 3' region of introns in pre-mRNA splicing of Saccharomyces cerevisiae.
1987 StandoutNobel
Yeast Exosome Mutants Accumulate 3′-Extended Polyadenylated Forms of U4 Small Nuclear RNA and Small Nucleolar RNAs
2000
Identification of specific nucleotide sequences and structural elements required for intronic U14 snoRNA processing.
1997
Specific small nuclear RNAs are associated with yeast spliceosomes
1986 StandoutNobel
Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase
1985 StandoutScienceNobel
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation.
1996 StandoutNobel
Deletion of a yeast small nuclear RNA gene impairs growth.
1985
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
2011 StandoutScienceNobel
Interactions of Small Nuclear RNA's with Precursor Messenger RNA During in Vitro Splicing
1992 Science
Spliceosome assembly in yeast.
1987
The Mating of a Fly
1994 StandoutScienceNobel
An essential yeast snRNA with a U5-like domain is required for splicing in vivo
1987
Elongation arrest is a physiologically important function of signal recognition particle
2000
Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.
1987
Splicing of Messenger RNA Precursors
1987 Science
Structural Analysis of the Human U3 Ribonucleoprotein Particle Reveal a Conserved Sequence Available for Base Pairing with Pre-rRna
1987
A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5′ cleavage site.
1988 StandoutNobel
Enzymatic activity of the conserved core of a group I self-splicing intron
1986 StandoutNatureNobel
Fractionation and characterization of a yeast mRNA splicing extract.
1986
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA
1987
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Oligomerization of Intervening Sequence RNA Molecules in the Absence of Proteins
1985 StandoutScienceNobel
Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth.
1989
Structural Features that Give Rise to the Unusual Stability of RNA Hairpins Containing GNRA Loops
1991 Science
Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes
1986 StandoutNatureNobel
Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro
1985
Works of Jo Ann Wise being referenced
The two similarly expressed genes encoding U3 snRNA in Schizosaccharomyces pombe lack introns.
1992
Molecular evolution of SRP cycle components: functional implications
1994
Mutations at the 3′ splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast
1992
The sequence of U3 fromSchizosaccharomyces pombesuggests structural divergence of this snRNA between metazoans and unicellular eukaryotes
1988
A simple high-efficiency method for random mutagenesis of cloned genes using forced nucleotide misincorporation
1990
The Srp54 GTPase is essential for protein export in the fission yeast Schizosaccharomyces pombe.
1994
The small nuclear RNAs of the cellular slime mold Dictyostelium discoideum. Isolation and characterization.
1981
Identification of an essential Schizosaccharomyces pombe RNA homologous to the 7SL component of signal recognition particle.
1988
[28] Preparation and analysis of low molecular weight RNAs and small ribonucleoproteins
1991
Identification of an Essential Schizosaccharomyces pombe RNA Homologous to the 7SL Component of Signal Recognition Particle
1988
Evolutionary Origin of the U6 Small Nuclear RNA Intron
1990
Dictyostelium small nuclear RNA D2 is homologous to rat nucleolar RNA U3 and is encoded by a dispersed multigene family
1980
Genetic analysis of Schizosaccharomyces pombe 7SL RNA: a structural motif that includes a conserved tetranucleotide loop is important for function.
1989
Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity.
1986
A U4-like small nuclear RNA is dispensable in yeast
1983
Yeast contains small nuclear RNAs encoded by single copy genes
1983
Functional interchangeability of the structurally similar tetranucleotide loops GAAA and UUCG in fission yeast signal recognition particle RNA.
1993
Random mutagenesis ofSchizosaccharomyces pombeSRP RNA: lethal and conditional lesions cluster in presumptive protein binding sites
1992
Guides to the Heart of the Spliceosome
1993 Science