Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
2011 StandoutScience
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
2010 StandoutScience
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Cancer and Altered Metabolism: Potential Importance of Hypoxia-Inducible Factor and 2-Oxoglutarate-Dependent Dioxygenases
2011 StandoutNobel
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
A role for CD95 ligand in preventing graft rejection
1995 StandoutNature
DNMT1 maintains progenitor function in self-renewing somatic tissue
2010 Nature
Control of somatic tissue differentiation by the long non-coding RNA TINCR
2012 StandoutNature
Epigenetic regulation of theINK4b-ARF-INK4alocus
2010
A view on drug resistance in cancer
2019 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
Polycomb group complexes – many combinations, many functions
2009
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Apoptosis by Death Factor
1997 Standout
Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers
2010
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
2009
The Use of Induced Pluripotent Stem Cells in Drug Development
2011 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Jumonji Modulates Polycomb Activity and Self-Renewal versus Differentiation of Stem Cells
2009
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs
2018
Jarid2 and PRC2, partners in regulating gene expression
2010
Molecular and cytogenetic analysis of chromosome 9 deletions in 75 malignant gliomas
1994
Cyclic di-GMP Sensing via the Innate Immune Signaling Protein STING
2012
PRC2 mediated H3K27 methylations in cellular identity and cancer
2015
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
1996 StandoutNature
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
A unique chromatin signature uncovers early developmental enhancers in humans
2010 StandoutNature
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
1995
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest
1994 StandoutNature
A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types
1994 StandoutScience
Autoimmune disease. a problem of defective apoptosis
1994
Genome-wide Analysis Reveals TET- and TDG-Dependent 5-Methylcytosine Oxidation Dynamics
2013
The Fas Death Factor
1995 StandoutScience
β-Arrestin1 Regulates Zebrafish Hematopoiesis through Binding to YY1 and Relieving Polycomb Group Repression
2009
Chromatin dynamics during cellular reprogramming
2013 Nature
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
2012 StandoutNobel
Chromatin as an oxygen sensor and active player in the hypoxia response
2011
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
Imbalance towards Th1 predominance is associated with acceleration of lupus-like autoimmune syndrome in MRL mice.
1996
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Fas Antigen and Sphingomyelin‐Ceramide Turnover‐Mediated Signaling: Role in Life and Death of T Lymphocytes1
1994
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Control of Life-or-Death Decisions by RIP1 Kinase
2013
Molecular analysis of deletions of the short arm of chromosome 9 in human gliomas.
1992
Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors
1997 StandoutScience
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.
1996
Chromatin and oxygen sensing in the context of JmjC histone demethylases
2014
Recruitment of Polycomb group complexes and their role in the dynamic regulation of cell fate choice
2009
STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
2012
Ezh2 Requires PHF1 To Efficiently Catalyze H3 Lysine 27 Trimethylation In Vivo
2008
Epigenetic Reprogramming in Cancer
2013 Science
Homozygous deletions within human chromosome band 9p21 in melanoma.
1992
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Homozygous deletions within 9p21-p22 identify a small critical region of chromosomal loss in human malignant mesotheliomas.
1993
Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview
2019
Cancer Genome Landscapes
2013 StandoutScience
CTLA-4 ligation blocks CD28-dependent T cell activation.
1996
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Wild-Type Human p53 and a Temperature-Sensitive Mutant Induce Fas/APO-1 Expression
1995
The Receptor for the Cytotoxic Ligand TRAIL
1997 StandoutScience
Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt
1997 StandoutScience
Immunological Memory and Protective Immunity: Understanding Their Relation
1996 StandoutScience
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D
2017 Science
Molecular definition of a chromosome 9p21 germ-line deletion in a woman with multiple melanomas and a plexiform neurofibroma: implications for 9p tumor-suppressor gene(s).
1993
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Mechanisms of Polycomb gene silencing: knowns and unknowns
2009
Jumonji C Demethylases in Cellular Senescence
2019
Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
2004 StandoutScience
Works of Jin He being referenced
Functional characterization of hepatoma‐specific stem cell antigen‐2
2004
Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
2013
The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b
2008
Direct, Noncatalytic Mechanism of IKK Inhibition by A20
2011
Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming
2012
Generation of Insulin-secreting Islet-like Clusters from Human Skin Fibroblasts
2008
Role of hPHF1 in H3K27 Methylation and Hox Gene Silencing
2007
KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia
2011
Chromosome 9 deletion mapping reveals interferon alpha and interferon beta-1 gene deletions in human glial tumors.
1991
Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice.
1994
DOT1L, the H3K79 methyltransferase, is required for MLL-AF9–mediated leukemogenesis
2011