Citation Impact
Citing Papers
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation
2003 StandoutNobel
In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker
2003 StandoutNobel
Consequences of the selective blockage of chaperone-mediated autophagy
2006
Liver injury in α1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury
2002
RAGE‐dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
Targeting autophagy in obesity: from pathophysiology to management
2018
Inflammation and Alzheimer's disease
2000 Standout
Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar β-amyloid
2001
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
2009
Modulation of anxiety through blockade of anandamide hydrolysis
2002 Standout
Apoptosis in the nervous system
2000 StandoutNature
Pharmacological Activity of Fatty Acid Amides Is Regulated, but Not Mediated, by Fatty Acid Amide Hydrolase in Vivo
2002
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
2001
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide
1999
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
2000 Nature
Oxidative Damage Is the Earliest Event in Alzheimer Disease
2001 Standout
At the acidic edge: emerging functions for lysosomal membrane proteins
2003
Regulation and role of autophagy in mammalian cells
2004
Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners
2004 Standout
Autophagic Vacuolar Myopathy
2006
The Human Homolog of Saccharomyces cerevisiae Apg7p Is a Protein-activating Enzyme for Multiple Substrates Including Human Apg12p, GATE-16, GABARAP, and MAP-LC3
2001
In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease
2000
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Differential regulation of microglial motility by ATP/ADP and adenosine
2009
Lamp-2a Facilitates MHC Class II Presentation of Cytoplasmic Antigens
2005
LC3 conjugation system in mammalian autophagy
2004 Standout
Microglia and inflammatory mechanisms in the clearance of amyloid β peptide
2002
Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain
2010
Circulating amyloid-β peptide crosses the blood–brain barrier in aged monkeys and contributes to Alzheimer's disease lesions
2002
Essential Roles of Atg5 and FADD in Autophagic Cell Death
2005
Characterization and Functional Analysis of the Promoter of RAGE, the Receptor for Advanced Glycation End Products
1997
Autophagy: Renovation of Cells and Tissues
2011 Standout
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
2007
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
2007
Amyloid-β Induces Chemotaxis and Oxidant Stress by Acting at Formylpeptide Receptor 2, a G Protein-coupled Receptor Expressed in Phagocytes and Brain
2001
Autophagy: a barrier or an adaptive response to cancer
2003
Pathogenesis of Human Mitochondrial Diseases Is Modulated by Reduced Activity of the Ubiquitin/Proteasome System
2014
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
2008
β-Amyloid1–42 Binds to α7 Nicotinic Acetylcholine Receptor with High Affinity
2000
The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis.
1996
Expression of Scavenger Receptors in Glial Cells
2005
Autophagy in the Pathogenesis of Disease
2008 Standout
Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.
1998
Autophagy in Human Health and Disease
2013 Standout
Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
2008
Autophagy and human disease: emerging themes
2014
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
RAGE, LRP-1, and amyloid-beta protein in Alzheimer’s disease
2006
Rapid impact of ?-amyloid on Paxillin in a neural cell line
1997
Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.
1997
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Physiological levels ofβ-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production
2001
The receptor for advanced glycation end‐products (RAGE) directly binds to ERK by a D‐domain‐like docking site
2003
Annexin 5 and apolipoprotein E2 protect against Alzheimer’s amyloid-β-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site
2002
Activation of Toll-like Receptor 2 on Microglia Promotes Cell Uptake of Alzheimer Disease-associated Amyloid β Peptide
2005
Microglia and Alzheimer's disease pathogenesis
2004
Alzheimer's Disease
2010 Standout
The cell biology of lysosomal storage disorders
2004
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Methods for monitoring autophagy
2004
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Sterile inflammation: sensing and reacting to damage
2010 Standout
Anti-inflammatory drugs and their mechanism of action
1998 Nobel
Mitochondrial dysfunction as a cause of optic neuropathies
2004
The role of autophagy in the heart
2008
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Association of Microglia with Amyloid Plaques in Brains of APP23 Transgenic Mice
1999
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
1999
Sp1-binding Elements in the Promoter of RAGE Are Essential for Amphoterin-mediated Gene Expression in Cultured Neuroblastoma Cells
1998
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
2000
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Bacterial interactions with the autophagic pathway
2002
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
?-Amyloid protein enhances macrophage production of oxygen free radicals and glutamate
1997
Liver injury in α1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury
2002
The First Molecular Evidence That Autophagy Relates Rimmed Vacuole Formation in Chloroquine Myopathy
2002 StandoutNobel
Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system
2003
Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins
2004
The Mouse APG10 Homologue, an E2-like Enzyme for Apg12p Conjugation, Facilitates MAP-LC3 Modification
2003
Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia
2004
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Involvement of Microglial Receptor for Advanced Glycation Endproducts (RAGE) in Alzheimer's Disease: Identification of a Cellular Activation Mechanism
2001
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
2000
Reciprocal Interactions Between Microglia and Neurons: From Survival to Neuropathology
2002
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Lysosomal myopathies: An excessive build-up in autophagosomes is too much to handle
2008
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
Inflammation and NF-κB in Alzheimer's Disease and Diabetes
2009
A Cell Surface Receptor Complex for Fibrillar β-Amyloid Mediates Microglial Activation
2003
Amyloid Fibrils Activate Tyrosine Kinase-Dependent Signaling and Superoxide Production in Microglia
1997
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death
2005
The Free Radical Theory of Aging Matures
1998 Standout
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Alzheimer's disease: a re-examination of the amyloid hypothesis
1998
Subacute NO generation induced by Alzheimer's β‐amyloid in the living brain: reversal by inhibition of the inducible NO synthase
2000
Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
2015
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
1998 Standout
RAGE (Yin) Versus LRP (Yang) Balance Regulates Alzheimer Amyloid β-Peptide Clearance Through Transport Across the Blood–Brain Barrier
2004
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.
2003
Structure-Based Design of a FAAH Variant That Discriminates between the N-Acyl Ethanolamine and Taurine Families of Signaling Lipids
2006
Cytochemical Demonstration of Oxidative Damage in Alzheimer Disease by Immunochemical Enhancement of the Carbonyl Reaction with 2,4-Dinitrophenylhydrazine
1998
Oxidative stress in glaucomatous neurodegeneration: Mechanisms and consequences
2006
Altered lipid content inhibits autophagic vesicular fusion
2010
Functional disassociation of the central and peripheral fatty acid amide signaling systems
2004
Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.
1998
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
A FAAH-Regulated Class of N-Acyl Taurines That Activates TRP Ion Channels
2006 StandoutNobel
Intracellular Functions of N-Linked Glycans
2001 StandoutScience
Myocytes Die by Multiple Mechanisms in Failing Human Hearts
2003
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
2009
Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease
1997
In VivoImaging of Reactive Oxygen Species Specifically Associated with Thioflavine S-Positive Amyloid Plaques by Multiphoton Microscopy
2003
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
2015 StandoutNobel
Role of LAMP-2 in Lysosome Biogenesis and Autophagy
2002
Increased Extracellular Amyloid Deposition and Neurodegeneration in Human Amyloid Precursor Protein Transgenic Mice Deficient in Receptor-Associated Protein
2002
Impaired Lipoprotein Receptor-Mediated Peripheral Binding of Plasma Amyloid-β is an Early Biomarker for Mild Cognitive Impairment Preceding Alzheimer's Disease
2011
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Autophagosome Formation in Mammalian Cells.
2002 StandoutNobel
Overcoming the Blood–Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases
2018
Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.
2001
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells
2001 StandoutNobel
Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells
2002
β-Amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1
2000
Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts
2004
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Cardiomyopathy with Prominent Autophagic Degeneration, Accompanied by an Elevated Plasma Brain Natriuretic Peptide Level Despite the Lack of Overt Heart Failure
2004
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
2005
Autophagy: Basic Principles and Relevance to Disease
2008
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
2009
Amyloid β42Activates a G-Protein-Coupled Chemoattractant Receptor, FPR-Like-1
2001
Fibrillar β-Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNSIn Vivo
1998
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins
1999
Chemical Glycoproteomics
2016 StandoutNobel
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
2011
Clearance of amyloid β-peptide from brain: transport or metabolism?
2000
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Jin Fu being referenced
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
2003 Nature
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
1995
Rescue of a deficiency in ATP synthesis by transfer of MTATP6, a mitochondrial DNA-encoded gene, to the nucleus
2002
A Stop-Codon Mutation in the Human mtDNA Cytochrome c Oxidase I Gene Disrupts the Functional Structure of Complex IV
1999
An anorexic lipid mediator regulated by feeding
2001 Nature
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)
2000 Nature
An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease
1997 Nature
Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
1997
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
Role of ERAB/l-3-Hydroxyacyl-coenzyme A Dehydrogenase Type II Activity in Aβ-induced Cytotoxicity
1999