Citation Impact
Citing Papers
NMR Structure Determination for Larger Proteins Using Backbone-Only Data
2010 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Property‐Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles**
2022
Inherent DNA ‐binding specificities of the HIF ‐1α and HIF ‐2α transcription factors in chromatin
2018 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Structural integration in hypoxia-inducible factors
2015 Nature
Chiral spiro Cu(i) complexes. Supramolecular stereocontrol and isomerisation dynamics by the use of TRISPHAT anions
2006 StandoutNobel
The role of dynamic conformational ensembles in biomolecular recognition
2009 Standout
Transcriptional architecture of the mammalian circadian clock
2016 Standout
Development of novel therapies for hepatitis C
2010
Mechanisms of hypoxia signalling: new implications for nephrology
2019 StandoutNobel
NMR-based screening technologies
2003
Structures of hepatitis C virus nonstructural proteins required for replicase assembly and function
2013 StandoutNobel
Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study
2004
The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
2013
CHARMM general force field: A force field for drug‐like molecules compatible with the CHARMM all‐atom additive biological force fields
2009 Standout
A compendium of proteins that interact with HIF-1α
2017 StandoutNobel
Heme Oxygenase-1 Protein Localizes to the Nucleus and Activates Transcription Factors Important in Oxidative Stress
2007
Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer
2017
Hepatitis C Virus Proteins: From Structure to Function
2013
Hepatitis C virus nonstructural protein 4B: a journey into unexplored territory
2010
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
Designing antimicrobial peptides: form follows function
2011 Standout
Pharmacological targeting of the HIF hydroxylases – A new field in medicine development
2016 StandoutNobel
Determining accurate molecular sizes in solution through NMR diffusion spectroscopy
2007 Standout
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
PROTAC targeted protein degraders: the past is prologue
2022 Standout
New function ofTSGA10gene in angiogenesis and tumor metastasis: a response to a challengeable paradox
2015
Intermolecular and Intramolecular Hydrogen Bonds Involving Fluorine Atoms: Implications for Recognition, Selectivity, and Chemical Properties
2012
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
The molecular landscape of head and neck cancer
2018 Standout
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
New insights into the role of Runx1 in epithelial stem cell biology and pathology
2012
Structure-based development of target-specific compound libraries
2006
Structural characterization of mammalian bHLH-PAS transcription factors
2016
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Polyguanidines as Chiral Orienting Media for Organic Compounds
2010
NMR Methods for Studying the Structure and Dynamics of RNA
2005
New opportunities in anti-hepatitis C virus drug discovery: Targeting NS4B
2011
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
Proteome-wide covalent ligand discovery in native biological systems
2016 Nature
Computer-based de novo design of drug-like molecules
2005
Nmr in drug discovery
2002 StandoutNobel
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Solution structure of an informationally complex high-affinity RNA aptamer to GTP
2006 StandoutNobel
Fluorine in medicinal chemistry
2007 Standout
Identification and Characterization of Small Molecule Inhibitors of the Calcium-Dependent S100B−p53 Tumor Suppressor Interaction
2004
Structure and Dynamic Properties of a Ti-Binding Peptide Bound to TiO2 Nanoparticles As Accessed by 1H NMR Spectroscopy
2016
Ion pairing using PGSE diffusion methods
2006
Mechanisms of Cell Protection by Heme Oxygenase-1
2010 Standout
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Molecular mechanisms of antimony resistance in Leishmania
2007
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
2020 Standout
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Design and NMR-Based Screening of LEF, a Library of Chemical Fragments with Different Local Environment of Fluorine
2009
Sequence–Structure–Binding Relationships Reveal Adhesion Behavior of the Car9 Solid-Binding Peptide: An Integrated Experimental and Simulation Study
2020 StandoutNobel
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein
2013
Residual Dipolar Couplings in Structure Determination of Biomolecules
2004
Identification of AP80978, a Novel Small-Molecule Inhibitor of Hepatitis C Virus Replication That Targets NS4B
2014 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Enantioselective palladium(0)-catalyzed intramolecular cyclopropane functionalization: access to dihydroquinolones, dihydroisoquinolones and the BMS-791325 ring system
2015
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Fast Hepatitis C Virus RNA Elimination and NS5A Redistribution by NS5A Inhibitors Studied by a Multiplex Assay Approach
2015 StandoutNobel
Characterization of Chemical Exchange Using Residual Dipolar Coupling
2007
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
2017
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
A Fragment-Based Method to Discover Irreversible Covalent Inhibitors of Cysteine Proteases
2014
TheC. elegansCBFβ homologue BRO-1 interacts with the Runx factor, RNT-1, to promote stem cell proliferation and self-renewal
2007
Conserved GXXXG- and S/T-Like Motifs in the Transmembrane Domains of NS4B Protein Are Required for Hepatitis C Virus Replication
2011
Targeting Protein–Protein Interactions in the HIF System
2016
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Parallel-Stacked Aromatic Hosts for Orienting Small Molecules in a Magnetic Field: Induced Residual Dipolar Coupling by Encapsulation
2010
Drug Resistance in Leishmaniasis
2006 Standout
Protein Allostery and Conformational Dynamics
2016
An Amphipathic α-Helix at the C Terminus of Hepatitis C Virus Nonstructural Protein 4B Mediates Membrane Association
2009
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Pulsed Gradient Spin−Echo (PGSE) Diffusion and 1H,19F Heteronuclear Overhauser Spectroscopy (HOESY) NMR Methods in Inorganic and Organometallic Chemistry: Something Old and Something New
2005
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Works of Jiangli Yan being referenced
Identification of Cys255 in HIF‐1α as a novel site for development of covalent inhibitors of HIF‐1α/ARNT PasB domain protein–protein interaction
2012
CBFβ allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium
2004
1D NMR Methods in Ligand-Receptor Interactions
2003
Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery
2011
Energetic Contribution of Residues in the Runx1 Runt Domain to DNA Binding
2003
MQ-HCN-based pulse sequences for the measurement of 13C1′-1H1′, 13C1′-15N, 1H1′-15N, 13C1′-13C2′, 1H1′-13C2′, 13C6/8-1H6/8, 13C6/8-15N, 1H6/8-15N, 13C6-13C5, 1H6-13C5 dipolar couplings in 13C, 15N-labeled DNA (and RNA)
2002
Application of residual dipolar couplings in organic compounds
2004
Using NMR for ligand discovery and optimization
2004
Homodimerization of the PAS-B Domains of Hypoxia-Inducible Factors
2012
A Novel Method for the Determination of Stereochemistry in Six-Membered Chairlike Rings Using Residual Dipolar Couplings
2003
Cyclic Peptide Design Guided by Residual Dipolar Couplings, J-Couplings, and Intramolecular Hydrogen Bond Analysis
2019
High Throughput Method for the Indirect Detection of Intramolecular Hydrogen Bonding
2014
The effect of relaxation on the epitope mapping by saturation transfer difference NMR
2003
Epitope Mapping of Ligand−Receptor Interactions by Diffusion NMR
2002
Biochemical Characterization of Recombinant Hepatitis C Virus Nonstructural Protein 4B: Evidence for ATP/GTP Hydrolysis and Adenylate Kinase Activity
2009
Complete Relative Stereochemistry of Multiple Stereocenters Using Only Residual Dipolar Couplings
2004
RAMPED-UP NMR: Multiplexed NMR-Based Screening for Drug Discovery
2003