Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt
2006 Standout
AKT Activation in Human Glioblastomas Enhances Proliferation via TSC2 and S6 Kinase Signaling
2006
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
2007 Standout
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Proliferation- and apoptosis-associated factors in advanced prostatic carcinomas before and after androgen deprivation therapy: prognostic significance of p21/WAF1/CIP1 expression
1999
Hypoxia-inducible Factor-1-dependent Overexpression of Myeloid Cell Factor-1 Protects Hypoxic Cells against tert-Butyl Hydroperoxide-induced Apoptosis
2004
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008 StandoutNature
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
Immunosuppressive networks in the tumour environment and their therapeutic relevance
2005 Standout
HIF-1: upstream and downstream of cancer metabolism
2009 StandoutNobel
A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy
2010
Genetic Alterations in Hormone-Refractory Recurrent Prostate Carcinomas
1998
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
2010 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Wnt signaling in cancer
2016 Standout
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
2008 Standout
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase
1999 StandoutNobel
Cancer drug resistance: an evolving paradigm
2013 Standout
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Pathological and molecular aspects of prostate cancer
2003
Inverse correlation of the up‐regulation of FZD10 expression and the activation of β‐catenin in synchronous colorectal tumors
2009
Molecular determinants of resistance to antiandrogen therapy
2003 Standout
The development of androgen-independent prostate cancer
2001 Standout
Bcl-2 Family Proteins: Strategies for Overcoming Chemoresistance in Cancer
1997
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Bax-dependent Regulation of Bak by Voltage-dependent Anion Channel 2
2005
Upstream and downstream of mTOR
2004 Standout
Regulation of Hypoxia-Inducible Factor-1α, Vascular Endothelial Growth Factor, and Angiogenesis by an Insulin-Like Growth Factor-I Receptor Autocrine Loop in Human Pancreatic Cancer
2003 StandoutNobel
The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death
1998
Overexpression of Bcl-xL Promotes Chemotherapy Resistance of Mammary Tumors in a Syngeneic Mouse Model
1999
p21 in cancer: intricate networks and multiple activities
2009 Standout
Cyclooxygenase-2 expression in endometrial cancer: Correlation with microvessel count and expression of vascular endothelial growth factor and thymidine phosphorylase
2002
Ki67 labeling index in core needle biopsies independently predicts tumor-specific survival in prostate cancer
1998
Molecular genetics of prostate cancer
2000
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Apoptosis
2002 Standout
Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins
2001
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Defining the Role of mTOR in Cancer
2007 Standout
The Ki-67 protein: From the known and the unknown
2000 Standout
Bcl-xL Blocks Transforming Growth Factor-β1-induced Apoptosis by Inhibiting Cytochrome c Release and Not by Directly Antagonizing Apaf-1-dependent Caspase Activation in Prostate Epithelial Cells
2001
Cancer and the chemokine network
2004 Standout
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
NF-κB at the crossroads of life and death
2002 Standout
A Role for Mitochondrial Bak in Apoptotic Response to Anticancer Drugs
2001
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
2004
Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes
2004 StandoutNobel
A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells
2005
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma.
2003
Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process.
1999
Expression of Mcl‐1 in mantle cell lymphoma is associated with high‐grade morphology, a high proliferative state, and p53 overexpression
2002
(−)-Gossypol enhances response to radiation therapy and results in tumor regression of human prostate cancer
2005
Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398.
2000
Enhanced Bone Regeneration Associated With Decreased Apoptosis in Mice With Partial HIF-1α Deficiency
2006 StandoutNobel
The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-xL
2000
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Hoxb13is required for normal differentiation and secretory function of the ventral prostate
2003 StandoutNobel
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
2010 StandoutNobel
Human immunodeficiency virus 1 favors the persistence of infection by activating macrophages through TNF
2004 StandoutNobel
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
2007 StandoutNobel
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues.
1998
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based Design
2012
Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture
2000
Mitotic spindle checkpoint inactivation by trichostatin A defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents
2005
Prospective Identification of Tumorigenic Prostate Cancer Stem Cells
2005 Standout
Works of JI Epstein being referenced
Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.
1996