Citation Impact
Citing Papers
Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial
2006
Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma
2010
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
2018 StandoutScienceNobel
Activation of Hypoxia-Inducible Factor-1 in Bacillary Angiomatosis
2005
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways.
2003 StandoutNobel
Induction chemotherapy in locally advanced squamous cell carcinoma of the head and neck: role, controversy, and future directions
2018
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene
2004 StandoutNobel
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Quantitative assessment of brown adipose tissue metabolic activity and volume using 18F-FDG PET/CT and β3-adrenergic receptor activation
2011
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
HIF‐1α and HIF‐2α have divergent roles in colon cancer
2008
Up‐regulation of gene expression by hypoxia is mediated predominantly by hypoxia‐inducible factor 1 (HIF‐1)
2005
Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma
2003
Angiopoietin-like protein 4: health effects, modulating agents and structure–function relationships
2012
Lymphoma-Specific Genetic Aberrations in Microvascular Endothelial Cells in B-Cell Lymphomas
2004
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
2002
Tumor-Associated Macrophages in Breast Cancer
2002
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Cancer Metastasis: Building a Framework
2006 Standout
Phase I/II Trial of Sequential Chemoradiotherapy Using a Novel Hypoxic Cell Radiosensitizer, Doranidazole (PR-350), in Patients With Locally Advanced Non–Small-Cell Lung Cancer (WJTOG-0002)
2007
Lung Cancer
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Hypoxia and Inflammation
2011 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Accelerated Radiotherapy, Carbogen, and Nicotinamide (ARCON) in the Treatment of Advanced Bladder Cancer: Mature Results of a Phase II Nonrandomized Study
2008
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Hypoxia-inducible factor 1 alpha–activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma
2011
Tumor Hypoxia and Malignant Progression
2004
Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
2007
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Induction Chemotherapy in Locally Advanced Head and Neck Cancer: A New Standard of Care?
2008
Treatment choice for locally advanced head and neck cancers on the basis of risk factors: biological risk factors
2012
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
2009
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
The Hypoxic Tumour Microenvironment, Patient Selection and Hypoxia-modifying Treatments
2007
Hypoxic gene expression and metastasis
2004
Radiation-/hypoxia-induced solid tumor metastasis and regrowth inhibited by hypoxia-specific upconversion nanoradiosensitizer
2015
ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer (EORTC)
2000
Transcriptional Regulation of Urokinase-type Plasminogen Activator Receptor by Hypoxia-Inducible Factor 1 Is Crucial for Invasion of Pancreatic and Liver Cancer
2009
Histology-Based Expression Profiling Yields Novel Prognostic Markers in Human Glioblastoma
2005
The von Hippel–Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
2002 StandoutNobel
Hypoxia, gene expression, and metastasis
2007
Sensitization of Hypoxic Tumors to Radiation Therapy Using Ultrasound-Sensitive Oxygen Microbubbles
2018
Hypoxic tumor cell radiosensitization through nitric oxide
2008
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis
2011
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Angiogenesis as a therapeutic target
2005 StandoutNature
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Cisplatin, Fluorouracil, and Docetaxel in Unresectable Head and Neck Cancer
2007 Standout
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis
2006 Standout
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Life with Oxygen
2007 StandoutScienceNobel
A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell
2011
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial
2012
Head and Neck Cancer
2020 Standout
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Expression of HIF-1α, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer
2005
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Expression of Concern: Bcl‐2 overexpression in human melanoma cells increases angiogenesis through VEGF mRNA stabilization and HIF‐1mediated transcriptional activity
2002
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.
2002
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
2004
Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness
2006
Artificial Molecular Machines
2015 Standout
Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(iv ) prodrugs
2014
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Baroreflex Failure
2005
Works of J.H.A.M. Kaanders being referenced
Improved Recurrence-Free Survival with ARCON for Anemic Patients with Laryngeal Cancer
2014
ARCON: accelerated radiotherapy with carbogen and nicotinamide in non small cell lung cancer: a phase I/II study by the EORTC
1999
Transcriptional Response to Hypoxia in Human Tumors
2001
ARCON: experience in 215 patients with advanced head-and-neck cancer
2002
Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer
1998
Clinical studies of hypoxia modification in radiotherapy
2004
Arterial baroreflex and peripheral chemoreflex function after radiotherapy for laryngeal or pharyngeal cancer
2002
Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescense based fiber-optic probes
2000
Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I–II feasibility study
2004
Induction chemotherapy with docetaxel/cisplatin/5-fluorouracil followed by randomization to two cisplatin-based concomitant chemoradiotherapy schedules in patients with locally advanced head and neck cancer (CONDOR study) (Dutch Head and Neck Society 08-01): A randomized phase II study
2015
Can FDG PET predict radiation treatment outcome in head and neck cancer? Results of a prospective study
2011
Administration of nicotinamide during a five- to seven-week course of radiotherapy: pharmacokinetics, tolerance, and compliance
1997
Screening for local and regional cancer recurrence in patients curatively treated for laryngeal cancer: Definition of a high‐risk group and estimation of the lead time
2006
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
2002